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Information
| Code | BT051 |
| Name | Clinical Applications of Molecular Genetic Methods - I |
| Term | 2024-2025 Academic Year |
| Term | Fall |
| Duration (T+A) | 3-2 (T-A) (17 Week) |
| ECTS | 6 ECTS |
| National Credit | 4 National Credit |
| Teaching Language | Türkçe |
| Level | Yüksek Lisans Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Doç. Dr. ATIL BİŞGİN |
| Course Instructor |
1 |
Course Goal / Objective
To have knowledge about methods based on PCR and to be able to evaluate their usage areas in health sciences
Course Content
the methods applied in Molecular genetic, clinical practice, application areas and practical applications
Course Precondition
None
Resources
Molecular genetics related on Articles
Notes
Molecular geneticsrelated on Articles/Books
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | To have general knowledge about PCR based methods |
| LO02 | Can use these methods |
| LO03 | To evaluate and analysis the studies |
| LO04 | Learns chemicals used in methods. |
| LO05 | It produces solutions to errors. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Based on the undergraduate level qualifications, develops and deepens the knowledge in the same or different field at the level of expertise and analyzes and interprets them using statistical methods. | 4 |
| PLO02 | Beceriler - Bilişsel, Uygulamalı | To identifiy the interdisciplinary interaction of the field and to solve use of the methods. | 4 |
| PLO03 | Beceriler - Bilişsel, Uygulamalı | Interpret the knowledge gained in the field by integrating the information from different disciplines and creates new information | 1 |
| PLO04 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Develops new strategic approaches for solving complex problems that are encountered in applications related to the field. | 4 |
| PLO05 | Yetkinlikler - Öğrenme Yetkinliği | To teach the social, scientific, cultural and ethical values during the collection, interpretation, implementation and announcement of the data related to the field. | |
| PLO06 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | To solve the problems encountered in the field and cominicate by using research methods. | |
| PLO07 | Yetkinlikler - Alana Özgü Yetkinlik | To gain the ability to develop and deepen the knowledge in the field of biotechnology | |
| PLO08 | Yetkinlikler - Alana Özgü Yetkinlik | Establishes functional interaction by using strategic decision-making processes in solving the problems encountered in the field. | |
| PLO09 | Yetkinlikler - Öğrenme Yetkinliği | Knows the ethical rules to be considered while obtaining biotechnological products. | |
| PLO10 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | He / she defends his / her original opinions in discussing the subjects in his / her field and establishes an effective communication showing his / her competence in the field. |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Introduction | No need for preliminary preparation | Öğretim Yöntemleri: Anlatım |
| 2 | Basic information about molecular genetic methods used in clinical practice | No need for preliminary preparation | Öğretim Yöntemleri: Anlatım |
| 3 | Genomic DNA/RNA isolation | No need for preliminary preparation | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 4 | DNA/RNA isolation from pathological tissues | No need for preliminary preparation | Öğretim Yöntemleri: Anlatım |
| 5 | liquid biopsy | No need for preliminary preparation | Öğretim Yöntemleri: Anlatım |
| 6 | general information about PCR | No need for preliminary preparation | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 7 | PCR-2 (Real time PCR, electrophoresis and restriction) (reverse, quantative) | No need for preliminary preparation | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 8 | Mid-Term Exam | No need for preliminary preparation | Ölçme Yöntemleri: Yazılı Sınav |
| 9 | Real time PCR | No need for preliminary preparation | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 10 | Droplet Digital PCR | No need for preliminary preparation | Öğretim Yöntemleri: Anlatım |
| 11 | experiment stages of DNA sequence analysis | No need for preliminary preparation | Öğretim Yöntemleri: Anlatım |
| 12 | Evaluation of DNA sequencing method | No need for preliminary preparation | Öğretim Yöntemleri: Anlatım, Tartışma |
| 13 | Practical use of sequencing methods and the use of data banks | No need for preliminary preparation | Öğretim Yöntemleri: Anlatım |
| 14 | presentation | No need for preliminary preparation | Öğretim Yöntemleri: Anlatım, Tartışma |
| 15 | presentation-2 | No need for preliminary preparation | Öğretim Yöntemleri: Anlatım, Tartışma |
| 16 | Term Exams | No need for preliminary preparation | Ölçme Yöntemleri: Yazılı Sınav |
| 17 | Term Exams | No need for preliminary preparation | Ölçme Yöntemleri: Yazılı Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 5 | 70 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 5 | 70 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 5 | 5 |
| Final Exam | 1 | 15 | 15 |
| Total Workload (Hour) | 160 | ||
| Total Workload / 25 (h) | 6,40 | ||
| ECTS | 6 ECTS | ||