Information
Code | ECS318 |
Name | Standardization and Quality Control Methods in Phytotherapeuticals |
Term | 2022-2023 Academic Year |
Semester | 6. Semester |
Duration (T+A) | 2-0 (T-A) (17 Week) |
ECTS | 2 ECTS |
National Credit | 2 National Credit |
Teaching Language | Türkçe |
Level | Lisans Dersi |
Type | Normal |
Mode of study | Yüz Yüze Öğretim |
Catalog Information Coordinator | Dr. Öğr. Üyesi TUBA ŞERBETÇİ |
Course Instructor |
Seçil KARAHÜSEYİN
(A Group)
(Ins. in Charge)
|
Course Goal / Objective
Comprehends the necessity and importance of the standardization process in herbal products, and the importance of chromatographic and other special analysis methods from a pharmacist's point of view.
Course Content
In order to get the desired benefit from the plants, it is necessary to process the right plant correctly and to prepare preparations / products with high efficiency, reliability and quality.
Course Precondition
none
Resources
Efficacy, safety, quality control, marketing and regulatory guidelines for herbal medicines (phytotherapeutic agents) Braz J Med Biol Res . 2000 Feb Phytotherapy and quality of herbal medicines, Fitoterapia, 2000 World Health Organization. (2011). Quality control methods for herbal materials. World Health Organization. https://apps.who.int/iris/handle/10665/44479 ders notları documents provided by lecturer
Notes
articles from literature
Course Learning Outcomes
Order | Course Learning Outcomes |
---|---|
LO01 | Explain the defiinition of quality for herbal preparations. |
LO02 | Give information about fferent formulations of phytotherapeuticals |
LO03 | Classify herbal medicines and give examples. |
LO04 | Explain standardization in phytotherapeuticals |
LO05 | Explain phytochemical evaluation methods for standardisation |
LO06 | Array the necessity of standardization |
LO07 | Explain the importance of good agricultural practice for phytotherapeuticals |
LO08 | Give information about the chromatographic techniques |
LO09 | Explain the quality-control methods present in Pharmacopeia |
LO10 | Give information about herbal monographs |
LO11 | Explain ash values quantification methods |
LO12 | Explain lost in drying methods |
LO13 | Explain the importance of heavy metals analyses |
LO14 | Explain the importance of microscopical examination |
LO15 | Explain phytochemical analyses and bioactive component quantification methods |
Relation with Program Learning Outcome
Order | Type | Program Learning Outcomes | Level |
---|---|---|---|
PLO01 | Bilgi - Kuramsal, Olgusal | Have sufficient knowledge in pharmaceutical field and develop the knowledge. | 4 |
PLO02 | Bilgi - Kuramsal, Olgusal | Comprehends professional knowledge with ethical responsibility through current laws and legislation. | |
PLO03 | Beceriler - Bilişsel, Uygulamalı | Provides consultancy service to patients, community and health care personnel and evaluates advanced knowledge and skills with a critical approach. | 3 |
PLO04 | Beceriler - Bilişsel, Uygulamalı | Possessing the knowledge of historical and current developments in the field of Pharmacy, monitoring, evaluation and application of scientific and evidence-based data, and adopting lifelong learning. | 3 |
PLO05 | Beceriler - Bilişsel, Uygulamalı | Have the knowledge and skills to help provide patient-oriented pharmacy applications and individualized pharmaceutical care by learning the basics of Clinical Pharmacy, | |
PLO06 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Takes a role in the evaluation and analysis of the events and cases related to the development of pharmacy profession and education. | 3 |
PLO07 | Yetkinlikler - Öğrenme Yetkinliği | Integrates and develops professional knowledge via different disciplines and uses the acquired knowledge to improve the health level and quality of life of the community. | 2 |
PLO08 | Yetkinlikler - Öğrenme Yetkinliği | Use effectively the concepts and applications of basic sciences and basic medical sciences in the field of medicine and pharmacy and update the information. | 2 |
PLO09 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Communicates effectively in writing and speaking. | 2 |
PLO10 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Practices the profession in accordance with Atatürk's principles and reforms, equipped with universal knowledge, uses Turkish correctly and knows at least one foreign language. | |
PLO11 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Be an example to society withexternal appearance, demeanor, attitude and behavior for the other professionals and society and with professional identity | 3 |
PLO12 | Yetkinlikler - Alana Özgü Yetkinlik | Have knowledge about health policies and health economics, pharmacy management and define the problems in pharmaceutical field. | 3 |
PLO13 | Yetkinlikler - Alana Özgü Yetkinlik | Interprets information about current health and treatment problems and attends meeting on related matters . Plays an active role in community health. | |
PLO14 | Yetkinlikler - Alana Özgü Yetkinlik | Acquires basic information about diseases, makes decisions about the drugs used in treatment in accordance with rational drug use. | 3 |
Week Plan
Week | Topic | Preparation | Methods |
---|---|---|---|
1 | Introduction to standardisaiton of phytotherapeuticals | Textbooks, current literature on the subject | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
2 | Adulteration/substitution, identity and purity | Textbooks, current literature on the subject | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
3 | Macro and microscopic examination for identification of right variety and search of adulterants. | Textbooks, current literature on the subject | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
4 | Foreign organic matter investigation | Textbooks, current literature on the subject | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
5 | Ash values, criteria to judge the identity and purity of crude drug | Textbooks, current literature on the subject | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
6 | Moisture content | Textbooks, current literature on the subject | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
7 | Extractive values and the effect of different methods to extrative values | Textbooks, current literature on the subject | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
8 | Mid-Term Exam | Subject repetition | Ölçme Yöntemleri: Ödev, Sözlü Sınav, Proje / Tasarım, Performans Değerlendirmesi |
9 | Qualitative chemical evaluation of crude drug with respect to phytochemical constituent | Textbooks, current literature on the subject | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
10 | Chromatographic examination: Include identification of crude drug based on the use of major chemical constituents as markers | Textbooks, current literature on the subject | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
11 | Quantitative chemical evaluation: To estimate the amount of the major classes of constituents. | Textbooks, current literature on the subject | Öğretim Yöntemleri: Soru-Cevap, Anlatım, Tartışma |
12 | The importance of analytical methods for the quality-control management of herbal drugs | Textbooks, current literature on the subject | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
13 | Other critical factors affecting the quality control of herbal drugs | Textbooks, current literature on the subject | Öğretim Yöntemleri: Soru-Cevap, Anlatım, Tartışma |
14 | Microbial contaminants and aflatoxins | Textbooks, current literature on the subject | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
15 | Good agricultural/Manufacturing practices | Textbooks, current literature on the subject | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
16 | Term Exams | Subject repetition | Ölçme Yöntemleri: Yazılı Sınav |
17 | Term Exams | Subject repetition | Ölçme Yöntemleri: Yazılı Sınav |
Student Workload - ECTS
Works | Number | Time (Hour) | Workload (Hour) |
---|---|---|---|
Course Related Works | |||
Class Time (Exam weeks are excluded) | 14 | 2 | 28 |
Out of Class Study (Preliminary Work, Practice) | 14 | 1 | 14 |
Assesment Related Works | |||
Homeworks, Projects, Others | 0 | 0 | 0 |
Mid-term Exams (Written, Oral, etc.) | 1 | 4 | 4 |
Final Exam | 1 | 8 | 8 |
Total Workload (Hour) | 54 | ||
Total Workload / 25 (h) | 2,16 | ||
ECTS | 2 ECTS |