ECS504 Pharmacogenetics

3 ECTS - 2-0 Duration (T+A)- 10. Semester- 2 National Credit

Information

Code ECS504
Name Pharmacogenetics
Term 2022-2023 Academic Year
Semester 10. Semester
Duration (T+A) 2-0 (T-A) (17 Week)
ECTS 3 ECTS
National Credit 2 National Credit
Teaching Language Türkçe
Level Lisans Dersi
Type Normal
Mode of study Yüz Yüze Öğretim
Catalog Information Coordinator Doç. Dr. FATMA AYDINOĞLU
Course Instructor Doç. Dr. FATMA AYDINOĞLU (A Group) (Ins. in Charge)


Course Goal / Objective

It is aimed to describe the basic concepts of pharmacogenetics, individual therapy, and the pharmacokinetic and pharmacodynamic properties of drugs, the role of genetic differences in drug interactions, and to explain and evaluate pharmacogenetics in the clinic.

Course Content

Genetic and environmental factors in individual variability, pharmacogenetic and individual therapy, the role of genetic factors in the pharmacokinetic/pharmacodinamic properties, the effect of genetic factors in individual drug responses, gene therapy

Course Precondition

None

Resources

Goodman and Gilman's The Pharmacological Basis of Therapeutics

Notes

Pubmed


Course Learning Outcomes

Order Course Learning Outcomes
LO01 Explain to pharmacogenetic and personalized therapy
LO02 Evaluate to the contribution of genetic and environmental factors in interpersonal variability in responses to drugs
LO03 Describe to the mechanism of genetic factors in changes in drug pharmacokinetics
LO04 To explain the alterations of drug pharmacodynamic due to genetic factors
LO05 Clarify to the possible enzyme polymorphism caused pharmacokinetic alterations
LO06 Give examples for the clarify to importance of pharmacogenetic in personalized therapy.
LO07 Explain to pharmacogenetic in clinical trials and pharmacogenetic tests
LO08 Describe to current studies in pharmacogenetic


Relation with Program Learning Outcome

Order Type Program Learning Outcomes Level
PLO01 Bilgi - Kuramsal, Olgusal Have sufficient knowledge in pharmaceutical field and develop the knowledge. 4
PLO02 Bilgi - Kuramsal, Olgusal Comprehends professional knowledge with ethical responsibility through current laws and legislation.
PLO03 Beceriler - Bilişsel, Uygulamalı Provides consultancy service to patients, community and health care personnel and evaluates advanced knowledge and skills with a critical approach. 3
PLO04 Beceriler - Bilişsel, Uygulamalı Possessing the knowledge of historical and current developments in the field of Pharmacy, monitoring, evaluation and application of scientific and evidence-based data, and adopting lifelong learning. 4
PLO05 Beceriler - Bilişsel, Uygulamalı Have the knowledge and skills to help provide patient-oriented pharmacy applications and individualized pharmaceutical care by learning the basics of Clinical Pharmacy, 2
PLO06 Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği Takes a role in the evaluation and analysis of the events and cases related to the development of pharmacy profession and education. 3
PLO07 Yetkinlikler - Öğrenme Yetkinliği Integrates and develops professional knowledge via different disciplines and uses the acquired knowledge to improve the health level and quality of life of the community. 5
PLO08 Yetkinlikler - Öğrenme Yetkinliği Use effectively the concepts and applications of basic sciences and basic medical sciences in the field of medicine and pharmacy and update the information. 5
PLO09 Yetkinlikler - İletişim ve Sosyal Yetkinlik Communicates effectively in writing and speaking. 3
PLO10 Yetkinlikler - İletişim ve Sosyal Yetkinlik Practices the profession in accordance with Atatürk's principles and reforms, equipped with universal knowledge, uses Turkish correctly and knows at least one foreign language. 3
PLO11 Yetkinlikler - İletişim ve Sosyal Yetkinlik Be an example to society withexternal appearance, demeanor, attitude and behavior for the other professionals and society and with professional identity 4
PLO12 Yetkinlikler - Alana Özgü Yetkinlik Have knowledge about health policies and health economics, pharmacy management and define the problems in pharmaceutical field. 1
PLO13 Yetkinlikler - Alana Özgü Yetkinlik Interprets information about current health and treatment problems and attends meeting on related matters . Plays an active role in community health. 3
PLO14 Yetkinlikler - Alana Özgü Yetkinlik Acquires basic information about diseases, makes decisions about the drugs used in treatment in accordance with rational drug use. 4


Week Plan

Week Topic Preparation Methods
1 Evaluation of the contribution of genetic and environmental factors in interpersonal variability in responses to drugs Reviews relevant book and literature Öğretim Yöntemleri:
Anlatım, Soru-Cevap
2 Pharmacogenetic and personalized therapy Reviews relevant book and literature Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Beyin Fırtınası
3 Current studies on individual differences, pharmacogenetics and individual treatment in response to drugs Reviews literature Öğretim Yöntemleri:
Soru-Cevap, Tartışma, Beyin Fırtınası
4 İnvestigation polymorphism of enzymes contributed to drug biotransformation Reviews relevant book and literature Öğretim Yöntemleri:
Soru-Cevap, Tartışma
5 Pharmacogenetic of trasnporter proteins Reviews relevant book and literature Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Beyin Fırtınası
6 Current literature on changes in genetic factors in drug pharmacokinetics Reviews literature Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Beyin Fırtınası
7 The alterations of drug pharmacodynamic due to genetic factors-1 Reviews relevant book and literature Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Beyin Fırtınası
8 Mid-Term Exam Ölçme Yöntemleri:
Yazılı Sınav
9 The alterations of drug pharmacodynamic due to genetic factors-2 Reviews relevant book and literature Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Beyin Fırtınası
10 Current literature on changes in genetic factors in drug pharmacodinamic Reviews literature Öğretim Yöntemleri:
Soru-Cevap, Tartışma, Beyin Fırtınası
11 The alterations of drug interactions due to genetic factors Reviews relevant book and literature Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Beyin Fırtınası
12 The importance of pharmacogenetics in personalized therapy Reviews relevant book and literature Öğretim Yöntemleri:
Anlatım, Soru-Cevap
13 Pharmacogenetic in clinical trials and pharmacogenetic tests Reviews relevant book and literature Öğretim Yöntemleri:
Anlatım, Soru-Cevap
14 Pharmacogenetic researches Reviews literature Öğretim Yöntemleri:
Anlatım, Tartışma, Beyin Fırtınası
15 Gene therapy and current studies Reviews literature Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Beyin Fırtınası
16 Term Exams Prsentations should be review Ölçme Yöntemleri:
Yazılı Sınav
17 Term Exams Presentation should be review. Ölçme Yöntemleri:
Yazılı Sınav


Student Workload - ECTS

Works Number Time (Hour) Workload (Hour)
Course Related Works
Class Time (Exam weeks are excluded) 14 2 28
Out of Class Study (Preliminary Work, Practice) 14 2 28
Assesment Related Works
Homeworks, Projects, Others 0 0 0
Mid-term Exams (Written, Oral, etc.) 1 6 6
Final Exam 1 16 16
Total Workload (Hour) 78
Total Workload / 25 (h) 3,12
ECTS 3 ECTS

Update Time: 21.11.2022 10:51