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Information
| Code | BY583 |
| Name | Molecular, Biochemical and Cellular Perspectives of Aquatic Toxicology |
| Term | 2022-2023 Academic Year |
| Term | Spring |
| Duration (T+A) | 3-0 (T-A) (17 Week) |
| ECTS | 6 ECTS |
| National Credit | 3 National Credit |
| Teaching Language | Türkçe |
| Level | Doktora Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Prof. Dr. MUSTAFA CANLI |
| Course Instructor |
1 |
Course Goal / Objective
To teach the toxic effects of metals on different molecules and vital biochemical processes
Course Content
toxic effects of heavy metals and pesticides in the aquatic environment, molecular, biochemical and cellular perspectives of toxicology, enzymology and molecular biology of xenobiotic-conjugating enzymes, biochemistry and molecular biology of monooxygenases, cellular responses in chronic toxicity, expression of oncogenes and tumor suppressor genes, DNA adduct analysis and mechanisms of metal regulation.
Course Precondition
None
Resources
Web of science
Notes
Internet
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Learn principles of toxicology |
| LO02 | Learn toxicology of metals and pesticides |
| LO03 | Learn response of enzymes to pollutants |
| LO04 | Learn response of genetic materials |
| LO05 | Learn molecular toxicology of pollutants |
| LO06 | Learn toxicokinetic of pollutants |
| LO07 | Learn free radicals and their effects on molecules |
| LO08 | Learn biomarkers in toxicology |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Based on the qualifications of the graduate, it develops and deepens the current and advanced knowledge in the field with original thought and / or research at the level of expertise and reaches the original definitions that will bring innovation to the field. | |
| PLO02 | Bilgi - Kuramsal, Olgusal | Evaluates, uses and transfers new information in the field with a systematic approach. | 1 |
| PLO03 | Bilgi - Kuramsal, Olgusal | Develops a new idea, method, design and / or application that brings innovation to the field, or applies a known idea, method, design and / or application to a different field, researches, comprehends, designs and applies an original topic. | |
| PLO04 | Bilgi - Kuramsal, Olgusal | Gains high level skills in using research methods in the field studies. | |
| PLO05 | Bilgi - Kuramsal, Olgusal | Makes critical analysis, synthesis and evaluation of new and complex thoughts. | 2 |
| PLO06 | Bilgi - Kuramsal, Olgusal | Extends the boundaries of knowledge in the field by publishing at least one scientific paper in national and / or international refereed journals and / or producing or interpreting an original work. | 2 |
| PLO07 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Examines and develops the social relations and the norms that direct these relations from a critical point of view. | 2 |
| PLO08 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Defends his / her original opinions in discussing the subjects in his / her field with experts, and establishes an effective communication showing his / her competence in his / her field. | 3 |
| PLO09 | Yetkinlikler - Öğrenme Yetkinliği | Introducing scientific, technological, social or cultural advances in the field; It contributes to the process of being a society of knowledge and sustaining it. | |
| PLO10 | Yetkinlikler - Öğrenme Yetkinliği | It contributes to the solution of social, scientific, cultural and ethical problems encountered in the field and supports the development of these values. | |
| PLO11 | Beceriler - Bilişsel, Uygulamalı | Develops new ideas and methods related to the field by using high level mental processes such as creative and critical thinking, problem solving and decision making. | 2 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | General Introduction | Current lecture notes, literature, internet | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 2 | Principles of toxicology1 | Current lecture notes, literature, internet | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 3 | Principles of toxicology2 | Current lecture notes, literature, internet | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 4 | Toxic effects of metals | Current lecture notes, literature, internet | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 5 | Toxic effects of pesticides | Current lecture notes, literature, internet | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 6 | Response of enzymes to metals | Current lecture notes, literature, internet | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 7 | Response of enzymes to pesticides | Current lecture notes, literature, internet | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 8 | Mid-Term Exam | Reading the notes | Ölçme Yöntemleri: Yazılı Sınav, Sözlü Sınav, Ödev |
| 9 | Molecular toxicology of metals | Current lecture notes, literature, internet | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 10 | Molecular toxicology of pesticides | Current lecture notes, literature, internet | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 11 | Genotoxicity of metals | Current lecture notes, literature, internet | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 12 | Genotoxicity of pesticides | Current lecture notes, literature, internet | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 13 | Free radicals and their toxic effects | Current lecture notes, literature, internet | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 14 | Biomarkers in toxiclogy | Current lecture notes, literature, internet | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 15 | Toxicokinetics of pollutants | Current lecture notes, literature, internet | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 16 | Term Exams | Reading the notes | Öğretim Yöntemleri: Tartışma |
| 17 | Term Exams | Reading the notes | Ölçme Yöntemleri: Yazılı Sınav, Sözlü Sınav, Ödev |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 3 | 42 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 5 | 70 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 15 | 15 |
| Final Exam | 1 | 30 | 30 |
| Total Workload (Hour) | 157 | ||
| Total Workload / 25 (h) | 6,28 | ||
| ECTS | 6 ECTS | ||