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Information
| Code | BY747 |
| Name | Oxidative stress ve antioxidant mechanisms |
| Term | 2022-2023 Academic Year |
| Term | Spring |
| Duration (T+A) | 2-0 (T-A) (17 Week) |
| ECTS | 6 ECTS |
| National Credit | 2 National Credit |
| Teaching Language | Türkçe |
| Level | Yüksek Lisans Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Prof. Dr. ELİF ORUÇ |
| Course Instructor |
1 |
Course Goal / Objective
Bölgemizde yaygın olarak kullanılan pestisitleri tanımak, etki şekilllerini, metabolizmalarını ve risk değerlendirmelerini göstermek
Course Content
oksijen radikallerive reaktif oksijen türleri nedir, oksijen radikallerin reaktiviteleri hücrede reaktif oksijen türlerinin üretimi hücre hasarı oxidantlar
Course Precondition
none
Resources
Oxidative stress and antioxidant defense S. Ahmad
Notes
Biochemistry Books
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Explains how reactive oxygen species occur in living organisms |
| LO02 | Understands the mode of action of oxidative stress |
| LO03 | Understand the molecular mechanisms about the diseases sourced by oxidative stress |
| LO04 | Understands the relationship between cell damage and oxidants |
| LO05 | Explain antioxidants and their functions |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Based on the undergraduate level qualifications, develops and deepens the knowledge in the same or different field at the level of expertise and analyzes and interprets them using statistical methods. | |
| PLO02 | Bilgi - Kuramsal, Olgusal | Identifies the interdisciplinary interaction that the field is related to. | |
| PLO03 | Bilgi - Kuramsal, Olgusal | Interprets the knowledge gained in the field by integrating the information from different disciplines and creates new information. | 3 |
| PLO04 | Bilgi - Kuramsal, Olgusal | Carries out a study that requires expertise related to the field independently. | 3 |
| PLO05 | Beceriler - Bilişsel, Uygulamalı | Evaluates the knowledge and skills acquired at the level of expertise in the field with a critical approach and directs its learning. | 4 |
| PLO06 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Supports the current developments in the field and their studies with quantitative and qualitative data and transmits them both in the field and outside the field systematically in written, oral and visual form. | 4 |
| PLO07 | Yetkinlikler - Öğrenme Yetkinliği | It supervises the social, scientific, cultural and ethical values in the collection, interpretation, application and announcement stages of the data related to the field and teaches these values. | 4 |
| PLO08 | Bilgi - Kuramsal, Olgusal | The information they absorbed in the field; use problem solving and / or practical skills in interdisciplinary studies. | 3 |
| PLO09 | Belirsiz | It contributes to the solution of social, scientific, cultural and ethical problems encountered in the field and supports the development of these values. | |
| PLO10 | Belirsiz | Develops new ideas and methods related to the field by using high level mental processes such as creative and critical thinking, problem solving and decision making. |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Oxygen radicals and reactive oxygen species | Study the relevant chapter in the book, Internet research should be done | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 2 | the mechanisms of reactive oxygen activation | Study the relevant chapter in the book, Internet research should be done | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 3 | Cell damage and oxidants | Study the relevant chapter in the book, Internet research should be done | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 4 | Reactive oxygen species | Study the relevant chapter in the book, Internet research should be done | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 5 | Pro-oxidants | Study the relevant chapter in the book, Internet research should be done | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 6 | enzymatic antioxidants | Study the relevant chapter in the book, Internet research should be done | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 7 | Non-enzymatic antioxidants | Study the relevant chapter in the book, Internet research should be done | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 8 | Mid-Term Exam | Ölçme Yöntemleri: Yazılı Sınav, Ödev |
|
| 9 | Glutathione | Study the relevant chapter in the book, Internet research should be done | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 10 | Glutathione S- transpherase | Study the relevant chapter in the book, Internet research should be done | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 11 | nitric oxide and oxidative stress | Study the relevant chapter in the book, Internet research should be done | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 12 | Calcium signal pathway and oxidative stress | Study the relevant chapter in the book, Internet research should be done | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 13 | Metals and oxidative stress | Study the relevant chapter in the book, Internet research should be done | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 14 | Selenoproteins | Study the relevant chapter in the book, Internet research should be done | Öğretim Yöntemleri: Soru-Cevap, Tartışma, Anlatım |
| 15 | Mitochondria and reactive oxygen species | Study the relevant chapter in the book, Internet research should be done | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 16 | Term Exams | Ölçme Yöntemleri: Ödev, Yazılı Sınav |
|
| 17 | Term Exams | Ölçme Yöntemleri: Yazılı Sınav, Ödev |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 2 | 28 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 6 | 84 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 2 | 6 | 12 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 6 | 6 |
| Final Exam | 1 | 12 | 12 |
| Total Workload (Hour) | 142 | ||
| Total Workload / 25 (h) | 5,68 | ||
| ECTS | 6 ECTS | ||