TÜRKÇE
ENGLISH
Information
| Code | BT0058 |
| Name | Human Biochemistry II |
| Term | 2022-2023 Academic Year |
| Semester | . Semester |
| Duration (T+A) | 2-2 (T-A) (17 Week) |
| ECTS | 6 ECTS |
| National Credit | 3 National Credit |
| Teaching Language | Türkçe |
| Level | Yüksek Lisans Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator |
Course Goal / Objective
Biochemistry seeks to describe the structure, organization and functions of living matter in molecular term. This course provides necessary information on major themes especially those relating to regulation and the relationship between structure and function, and regulation of metabolism.
Course Content
Introduction to metabolism, Carbohydrate metabolism, Carbohydrate metabolism, Lipid metabolism, Amino acid metabolism, Nucleotide metabolism, Heme metabolism and its importance, Biochemistry of original organs and systems, Clinical Biochemistry
Course Precondition
None
Resources
İnsan Biyokimyası. Editörler: Onat T, Emerk K, Sözmen EY). Palme Yayıncılık 2002, Ankara.
Notes
David Nelson , Michael M. Cox. Biyokimyanın İlkeleri, Palme Yayınevi, ISBN:9786053551393, 2016
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Defines the formation and destruction pathways in carbohydrate metabolism. |
| LO02 | Explain the production of energy in living organisms and the functioning of metabolism according to bioenergetic principles. |
| LO03 | Defines the formation and destruction pathways in lipid metabolisms. |
| LO04 | Defines the formation and destruction pathways in amino acid and nucleotide metabolisms. |
| LO05 | Explain the transfer of information in the cell, RNA and protein metabolism and control of gene expression. |
| LO06 | Defines the hormonal control of metabolism and its integration at the organism level. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Based on the undergraduate level qualifications, develops and deepens the knowledge in the same or different field at the level of expertise and analyzes and interprets them using statistical methods. | 5 |
| PLO02 | Beceriler - Bilişsel, Uygulamalı | To identifiy the interdisciplinary interaction of the field and to solve use of the methods. | |
| PLO03 | Beceriler - Bilişsel, Uygulamalı | Interpret the knowledge gained in the field by integrating the information from different disciplines and creates new information | |
| PLO04 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Develops new strategic approaches for solving complex problems that are encountered in applications related to the field. | |
| PLO05 | Yetkinlikler - Öğrenme Yetkinliği | To teach the social, scientific, cultural and ethical values during the collection, interpretation, implementation and announcement of the data related to the field. | |
| PLO06 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | To solve the problems encountered in the field and cominicate by using research methods. | 3 |
| PLO07 | Yetkinlikler - Alana Özgü Yetkinlik | To gain the ability to develop and deepen the knowledge in the field of biotechnology | |
| PLO08 | Yetkinlikler - Alana Özgü Yetkinlik | Establishes functional interaction by using strategic decision-making processes in solving the problems encountered in the field. | |
| PLO09 | Yetkinlikler - Öğrenme Yetkinliği | Knows the ethical rules to be considered while obtaining biotechnological products. | |
| PLO10 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | He / she defends his / her original opinions in discussing the subjects in his / her field and establishes an effective communication showing his / her competence in the field. |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Enter to metabolism | Lecture notes | Öğretim Yöntemleri: Soru-Cevap |
| 2 | Protein and amino acid metabolism: nitrogen fixation and balance, digestion, absorption and degradation of proteins, General amino acid reactions: deamination, transamination, decarboxylation, elimination, urea cycle and catabolism of amino acids | Lecture notes | Öğretim Yöntemleri: Soru-Cevap |
| 3 | Oxidative decarboxylation and citrate cycle, regulation, glyoxylate cycle | Lecture notes | Öğretim Yöntemleri: Soru-Cevap |
| 4 | Carbohydrate metabolism; digestion/absorption, glycolysis/aerobic/anaerobic), gluconeogenesis, regulation, Cori cycle | Lecture notes | Öğretim Yöntemleri: Soru-Cevap |
| 5 | Pentose phosphate pathway: oxidative and non-oxidative reactions, regulation and Calvin cycle | Lecture notes | Öğretim Yöntemleri: Soru-Cevap |
| 6 | Glycogen metabolism: Glycogen structure and physiological importance, glucose homeostasis, glycogenesis and glycogenolysis, regulation, glycogen storage diseases | Lecture notes | Öğretim Yöntemleri: Soru-Cevap |
| 7 | Lipid Metabolism: Lipid chemistry and nomenclature, digestion, absorption, distribution, catabolism of saturated, unsaturated and branched fatty acids, ketogenesis, fatty acid biosynthesis, regulation, synthesis of other lipids, and lipid storage diseases | Lecture notes | Öğretim Yöntemleri: Soru-Cevap |
| 8 | Mid-term exam | Lecture notes | Ölçme Yöntemleri: Yazılı Sınav |
| 9 | Lipid Metabolism:isoprenoid lipids, steroids and carotenoids, Cholesterol and sterol metabolism and control | Lecture notes | Öğretim Yöntemleri: Soru-Cevap |
| 10 | Biological membranes and cellular transport | Lecture notes | Öğretim Yöntemleri: Soru-Cevap |
| 11 | Electron transport chain, oxidative phosphorylation and photosynthesis | Lecture notes | Öğretim Yöntemleri: Tartışma |
| 12 | Integration of metabolism | Lecture notes | Öğretim Yöntemleri: Tartışma |
| 13 | Nucleic acids structure and function, gene therapy | Lecture notes | Öğretim Yöntemleri: Tartışma |
| 14 | Gene and genome concepts | Lecture notes | Öğretim Yöntemleri: Tartışma |
| 15 | Stem cells and cloning | Lecture notes | Öğretim Yöntemleri: Tartışma |
| 16 | Hormone receptors and signal transduction | Lecture notes | Öğretim Yöntemleri: Tartışma |
| 17 | Final Exam | Lecture notes | Ölçme Yöntemleri: Performans Değerlendirmesi |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 4 | 56 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 4 | 56 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 1 | 2 | 2 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 12 | 12 |
| Final Exam | 1 | 28 | 28 |
| Total Workload (Hour) | 154 | ||
| Total Workload / 25 (h) | 6,16 | ||
| ECTS | 6 ECTS | ||