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Information
| Code | BFZ640 |
| Name | Cell Biophysics II |
| Term | 2022-2023 Academic Year |
| Term | Spring |
| Duration (T+A) | 2-2 (T-A) (17 Week) |
| ECTS | 7 ECTS |
| National Credit | 3 National Credit |
| Teaching Language | Türkçe |
| Level | Doktora Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Prof.Dr. İSMAİL GÜNAY |
| Course Instructor |
1 |
Course Goal / Objective
To be able to analyze the basic bioelectric and biomechanical phenomena in the cell with biophysical methods
Course Content
Structure of atom, intermolecular forces, diffusion, osmosis, structure of cell membrane, transport of matter through cell membrane, mechanism of formation of resting membrane potential and Nernst equation, GHK equation and stationary state, ion channels, channel blockers, microelectrode, voltage-clamping and patch-clamping methods
Course Precondition
There is no prerequisite for the lesson
Resources
Lecture notes (For Medical Faculty Students - İsmail Günay) Biophysics (Ferit Pehlivan) Biophysics (Gürbüz Çelebi) Internet Search
Notes
Internet Research
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Understand the importance of molecular bonds |
| LO02 | Knows the mechanism of substance passing through membrane |
| LO03 | discuss the mechanism of formation of resting membrane potential |
| LO04 | Discusses the advantages of intracellular recording method |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | To learn the basic information about the field | 5 |
| PLO02 | Bilgi - Kuramsal, Olgusal | To be able to establish experimental work in laboratory | 5 |
| PLO03 | Bilgi - Kuramsal, Olgusal | To prepare a project proposal by itself | 4 |
| PLO04 | Bilgi - Kuramsal, Olgusal | To plan an experimental research | 5 |
| PLO05 | Bilgi - Kuramsal, Olgusal | To make a report as a result of the research | 5 |
| PLO06 | Bilgi - Kuramsal, Olgusal | To be able to interpret research findings | 5 |
| PLO07 | Bilgi - Kuramsal, Olgusal | Having analytical thinking mechanism related to the field Accessing reliable information Creating and writing a research project Study and research based on ethic values | 5 |
| PLO08 | Bilgi - Kuramsal, Olgusal | Ability to transfer the theoretical knowledge to the audience in a systematic way | 5 |
| PLO09 | Bilgi - Kuramsal, Olgusal | To have scientific thought systematic about the profession | 5 |
| PLO10 | Bilgi - Kuramsal, Olgusal | Kendi başına bir proje önerisi hazırlayabilmek | 5 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Structure of atom | Related topic read | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 2 | Intermolecular forces and bonds | Related topic read | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 3 | diffusion, ozmos | Related topic read | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 4 | Structure and function of cell membrane | Related topic read | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 5 | Particle transport from cell membrane | Related topic read | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 6 | The mechanism of formation of resting membrane potential and the Nernst equation | Related topic read | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 7 | GHK equation and case | Related topic read | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Beyin Fırtınası |
| 8 | Mid-Term Exam | Ölçme Yöntemleri: Yazılı Sınav, Ödev |
|
| 9 | ion channels | Related topic read | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Deney / Laboratuvar |
| 10 | Channel blockers | Related topic read | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Deney / Laboratuvar |
| 11 | microelectrode recording method | Related topic read | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Alıştırma ve Uygulama |
| 12 | voltage-clamp and patch-clamp recording methods | Related topic read | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 13 | Homework2 | Related topic read | Ölçme Yöntemleri: Performans Değerlendirmesi, Sözlü Sınav |
| 14 | The relationship between ion concentration and membrane potential | Related topic read | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 15 | Hodgkin-Huxley dice model | Related topic read | |
| 16 | Term Exams | Ölçme Yöntemleri: Yazılı Sınav, Ödev |
|
| 17 | Term Exams | Ölçme Yöntemleri: Yazılı Sınav, Ödev |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 4 | 56 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 6 | 84 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 1 | 9 | 9 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 8 | 8 |
| Final Exam | 1 | 16 | 16 |
| Total Workload (Hour) | 173 | ||
| Total Workload / 25 (h) | 6,92 | ||
| ECTS | 7 ECTS | ||