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Information
| Code | BFZ553 |
| Name | Measurement and Recording of Mechanical Activities in Rat Muscles |
| Term | 2022-2023 Academic Year |
| Semester | . Semester |
| Duration (T+A) | 2-2 (T-A) (17 Week) |
| ECTS | 5 ECTS |
| National Credit | 3 National Credit |
| Teaching Language | Türkçe |
| Level | Yüksek Lisans Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Prof. Dr. IŞIL ÖCAL |
Course Goal / Objective
According to human anatomical and physiological structure to learn the smooth muscles of the experimental animals, to isolate the rat artery aorta and uterus muscles, anesthetic and pharmacological agents to measure and record the effects of mechanical activity on the smooth muscles.
Course Content
The experimental animals used in biophysical research, the smooth muscles used in the experimental animals and the anatomy and physiology of these muscles are described.
Course Precondition
There is no prerequisite for the lesson
Resources
Surgical Research (Research Planning, Evaluation and Presentation, Experimental Animals, Specific Experimental Models Nobel Bookstore, Turkey 2005
Notes
Internet Research
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Knows the smooth muscles in using the experimental animals and anatomical and physiological structures of these smooth muscles |
| LO02 | Knows the anatomical and physiological properties of smooth muscle of rat vascular aorta and uterus. |
| LO03 | Knows the mechanical properties of rat aorta muscle. |
| LO04 | Knows the dissection of the isolated aorta muscle of the rat and preparation of the preparation. |
| LO05 | Knows the instruments used to measure and record the mechanical properties of the isolated aorta muscle of the rat. |
| LO06 | Knows the pharmacological agents used to generate contraction and relaxation parameters of the rat in isolated aorta muscle. |
| LO07 | Knows the preparation and recording of the isolated aorta preparation of the rat in the organ bath. |
| LO08 | Knows the preparation of pharmacological agents to be added to Organ Bath. |
| LO09 | Learn how pregnancy is formed in rats. |
| LO10 | Knows how to isolate uterus muscle in pregnant and normal rats. |
| LO11 | Knows the placement of the uterine muscle of the rat in the organ bath. |
| LO12 | Knows the pharmacological agents used to record the mechanical activity of the rat in the uterus. |
| LO13 | Knows the instruments used to measure and record the mechanical properties of rat uterus muscle. |
| LO14 | Knows the pharmacological agents used to create contraction and relaxation parameters of rat in uterine muscle. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Learns basic information about the field | 5 |
| PLO02 | Bilgi - Kuramsal, Olgusal | Sets up and works experimental setups in the laboratory | 5 |
| PLO03 | Bilgi - Kuramsal, Olgusal | Prepares a project proposal on its own | 5 |
| PLO04 | Bilgi - Kuramsal, Olgusal | Plans an experimental study | 5 |
| PLO05 | Bilgi - Kuramsal, Olgusal | Reports the research result | 5 |
| PLO06 | Bilgi - Kuramsal, Olgusal | Interpret the research findings | 4 |
| PLO07 | Beceriler - Bilişsel, Uygulamalı | Has the analytical thinking mechanism related to the field, Reaches reliable information. Creates and writes a research project, works and researches based on ethical values. | 5 |
| PLO08 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | She/he systematically transfers the theoretical knowledge she has researched to the audience. | 4 |
| PLO09 | Yetkinlikler - Öğrenme Yetkinliği | Have a scientific thinking systematic in relation to their profession. | 5 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | The smooth muscles of animals used in experimental research | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Gösteri, Deney / Laboratuvar |
| 2 | Comparison of anatomical and physiological features of rat vascular aorta and uterus smooth muscles with human smooth muscles | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Gösteri, Deney / Laboratuvar |
| 3 | Mechanical properties of rat aorta smooth muscle | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Gösteri, Deney / Laboratuvar |
| 4 | Dissection of rat isolated aorta muscle and preparation of preparations | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Gösteri, Deney / Laboratuvar |
| 5 | Rat Instruments for measuring and recording the mechanical properties of isolated aorta muscle (contraction-relaxation) | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Gösteri, Deney / Laboratuvar |
| 6 | Pharmacological agents used to generate contraction and relaxation parameters in rat isolated aorta muscle | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Gösteri, Deney / Laboratuvar |
| 7 | Preparation of anesthetic and physiological agents affecting rat isolated aorta preparation | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Gösteri, Deney / Laboratuvar |
| 8 | Mid-Term Exam | Öğretim Yöntemleri: Alıştırma ve Uygulama |
|
| 9 | Muscle contraction with different pharmacological agents in rat aorta muscle | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Gösteri, Deney / Laboratuvar |
| 10 | Muscle relaxation with different pharmacological agents in rat aorta muscle | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Gösteri, Deney / Laboratuvar |
| 11 | Pregnant rat formation and characteristics of the uterine muscle | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Gösteri, Deney / Laboratuvar |
| 12 | Comparison and control activities of pregnant rat uterus muscle and normal rat uterus muscle | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Gösteri, Deney / Laboratuvar |
| 13 | Instruments used in the measurement and recording of mechanical activities in rat uterine muscle | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Gösteri, Deney / Laboratuvar |
| 14 | Recording of the effects of different pharmacological and anesthetic agents on mechanical activities in rat uterine muscle | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Gösteri, Deney / Laboratuvar |
| 15 | Evaluation of the mechanical activity of rat uterus smooth muscle | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Gösteri, Deney / Laboratuvar |
| 16 | Term Exams | Ölçme Yöntemleri: Yazılı Sınav, Ödev, Performans Değerlendirmesi |
|
| 17 | Term Exams | Ölçme Yöntemleri: Yazılı Sınav, Ödev, Performans Değerlendirmesi |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 4 | 56 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 3 | 42 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 1 | 3 | 3 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 8 | 8 |
| Final Exam | 1 | 16 | 16 |
| Total Workload (Hour) | 125 | ||
| Total Workload / 25 (h) | 5,00 | ||
| ECTS | 5 ECTS | ||