Trans554 Cell Signaling Pathways

5 ECTS - 3-0 Duration (T+A)- . Semester- 3 National Credit

Information

Code Trans554
Name Cell Signaling Pathways
Term 2022-2023 Academic Year
Semester . Semester
Duration (T+A) 3-0 (T-A) (17 Week)
ECTS 5 ECTS
National Credit 3 National Credit
Teaching Language İngilizce
Level Yüksek Lisans Dersi
Type Normal
Mode of study Yüz Yüze Öğretim
Catalog Information Coordinator


Course Goal / Objective

All students who take the course should acquire basic information about intercellular communication and intracellular signaling pathways, learn the biotechnological uses of this information and follow the researches on this subject.

Course Content

Definitions of receptor and signal, receptor types, intercellular messengers, intracellular signal transduction mechanisms, receptor activation and inactivation mechanisms, principles of signal cascade, oncogenic and tumor suppressor signals and mutations, methods of targeting signal pathways for therapeutic purposes in cancer, article review and presentation .

Course Precondition

Resources

Notes



Course Learning Outcomes

Order Course Learning Outcomes
LO01 Gain knowledge about the role of signal transduction at every stage from DNA repair to cell division, targeting methods of signal transduction pathways in the treatment of diseases and their use in the field of Translational Medicine by using interactive and research-based learning methods.
LO02 In this course, students understand the mechanism of the biological behavior of cells, the receptors that affect these behaviors, the signals and how the transmission is done.
LO03 Learns the evaluation of scientific articles on the related field and make article presentations


Relation with Program Learning Outcome

Order Type Program Learning Outcomes Level
PLO01 Bilgi - Kuramsal, Olgusal Develops and deepens knowledge in the field of translational medicine to the proficiency level based on bachelor-level qualifications.
PLO02 Bilgi - Kuramsal, Olgusal Conceives the interdisciplinary interaction in which the field is related to translational medicine
PLO03 Bilgi - Kuramsal, Olgusal Knows the information technologies, technical equipment, and field-specific devices and instruments at the level required by the field of Translational Medicine.
PLO04 Bilgi - Kuramsal, Olgusal Knows statistics as a tool that is constantly used in studies in the field of Translational Medicine, and uses relevant software effectively.
PLO05 Beceriler - Bilişsel, Uygulamalı Uses of theoretical and practical knowledge within the field at a proficiency level.
PLO06 Beceriler - Bilişsel, Uygulamalı Interprets the knowledge about the field by integrating the information gathered from different disciplines and formulates new knowledge.
PLO07 Beceriler - Bilişsel, Uygulamalı Makes necessary investigations by using tools, devices, and instruments required for knowledge and technologies about translational medicine and related disciplines at an advanced level; develops a new and creative solution (device, method, treatment, drug) for the problems.
PLO08 Beceriler - Bilişsel, Uygulamalı Solves the problem faced related to the field by using research methods.
PLO09 Beceriler - Bilişsel, Uygulamalı Plans and conducts an experimental study.
PLO10 Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği Takes responsibility and develops new strategic solutions as a team member in order to solve unexpected complex problems faced within the applications in the field, evaluates the results, and applies when necessary.
PLO11 Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği Conducts scientific studies in translational medicine and related fields independently or as a team member.
PLO12 Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği Publishes a scientific paper in a national journal or presents it at a scientific meeting.
PLO13 Yetkinlikler - Öğrenme Yetkinliği Evaluates knowledge and skills acquired at proficiency level in the field with a critical approach and direct the learning.
PLO14 Yetkinlikler - Öğrenme Yetkinliği Applies the principles of advanced professional development and lifelong learning in the field of Translational Medicine.
PLO15 Yetkinlikler - İletişim ve Sosyal Yetkinlik Communicates current developments and studies within the field to both professional and non-professional groups systematically using written, oral and visual techniques by supporting quantitative and qualitative data.
PLO16 Yetkinlikler - İletişim ve Sosyal Yetkinlik Communicates and discusses orally, in writing, and visually with peers by using a foreign language at least at a level of European Language Portfolio B2 General Level.
PLO17 Yetkinlikler - Alana Özgü Yetkinlik Develops strategy, policy, and implementation plans on the issues related to the field and assess the findings within the frame of quality processes and ethics.


Week Plan

Week Topic Preparation Methods
1 Aims and objectives of cellular signal transmission course, discussion of course content and plan, students' expectations. Definitions related to cell signaling Öğretim Yöntemleri:
Soru-Cevap
2 Types of intercellular communication – cytokines and peptide messengers Öğretim Yöntemleri:
Grup Çalışması
3 Types of intercellular communication – genomic messengers Öğretim Yöntemleri:
Grup Çalışması
4 Types of receptors Öğretim Yöntemleri:
Tartışma
5 Receptor tyrosine kinase family Öğretim Yöntemleri:
Grup Çalışması
6 G-protein coupled receptors Öğretim Yöntemleri:
Grup Çalışması
7 Intracellular signaling pathways Öğretim Yöntemleri:
Grup Çalışması
8 Mid-Term Exam Ölçme Yöntemleri:
Sözlü Sınav
9 Receptor activation and inactivation Öğretim Yöntemleri:
Grup Çalışması
10 Oncogenic and tumor suppressor signals Öğretim Yöntemleri:
Grup Çalışması
11 Techniques to study cell signaling Öğretim Yöntemleri:
Grup Çalışması
12 DNA Repair System signaling Öğretim Yöntemleri:
Grup Çalışması
13 Epigenetics and signaling Öğretim Yöntemleri:
Grup Çalışması
14 Small RNAs and signaling Öğretim Yöntemleri:
Grup Çalışması
15 Article presentations Öğretim Yöntemleri:
Bireysel Çalışma
16 Term Exams Ölçme Yöntemleri:
Ödev
17 Term Exams Ölçme Yöntemleri:
Yazılı Sınav


Student Workload - ECTS

Works Number Time (Hour) Workload (Hour)
Course Related Works
Class Time (Exam weeks are excluded) 14 3 42
Out of Class Study (Preliminary Work, Practice) 14 3 42
Assesment Related Works
Homeworks, Projects, Others 0 0 0
Mid-term Exams (Written, Oral, etc.) 1 12 12
Final Exam 1 18 18
Total Workload (Hour) 114
Total Workload / 25 (h) 4,56
ECTS 5 ECTS

Update Time: 14.11.2022 10:25