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Information
| Code | BİO645 |
| Name | Gene - Genome and Proteome |
| Term | 2022-2023 Academic Year |
| Term | Spring |
| Duration (T+A) | 3-0 (T-A) (17 Week) |
| ECTS | 5 ECTS |
| National Credit | 3 National Credit |
| Teaching Language | Türkçe |
| Level | Doktora Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Prof. Dr. HÜSNÜ ÜMİT LÜLEYAP |
| Course Instructor |
1 |
Course Goal / Objective
Form the necessary background for understanding properties, differences of gene and genome structure and understanding the relationship with diseases.
Course Content
Gene structure, active genes, evolution of genes with introns, Evolution and Exons, Domain, Species complexity and Gene number, Essential gene number and its importance. The relationship between protein size and genome and complexity, genome structure, genome, transcriptome, proteome and protein protein interaction concepts, genomic size, human genome, genomics and proteomics, protein properties and proteomics, Why Proteome, The relationship between homology and protein structure and function, applications in proteomics and medicine, proteome studies and stages, proteome techniques,
Course Precondition
Resources
Notes
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Knows the terms-ending in -omics, such as genomics, proteomics or metabolomics |
| LO02 | Is able to understand connections between genomics, proteomics and metabolomics |
| LO03 | Knows the projects done in the field of omics |
| LO04 | Knows the connections between Omics and complex diseases |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | To make and interpret Medical Genetics, Molecular Genetics and Cytogenetic analyzes | 3 |
| PLO02 | Bilgi - Kuramsal, Olgusal | To have information about genetic diseases | 3 |
| PLO03 | Bilgi - Kuramsal, Olgusal | To have knowledge of Molecular Cell Biology | 3 |
| PLO04 | Bilgi - Kuramsal, Olgusal | To apply fluorescence in-situ hybridization (FISH) technique | 1 |
| PLO05 | Bilgi - Kuramsal, Olgusal | To make DNA isolation and PCR of all kinds of tissue | 1 |
| PLO06 | Bilgi - Kuramsal, Olgusal | To make cell culture of all kinds of tissue (blood, amniotic fluid, chorionic villus biopsy) | 2 |
| PLO07 | Bilgi - Kuramsal, Olgusal | To do cytogenetic analysis by recognizing human chromosomes separately | 2 |
| PLO08 | Bilgi - Kuramsal, Olgusal | To make QF-PCR and to interpret the results | 2 |
| PLO09 | Bilgi - Kuramsal, Olgusal | To have the knowledge and skills to teach Medical Biology and Genetics Courses in Medical Faculties | 1 |
| PLO10 | Bilgi - Kuramsal, Olgusal | To write and implement a research project on his/her own | 1 |
| PLO11 | Bilgi - Kuramsal, Olgusal | To write an article by collecting the information obtained at the end of the research | 2 |
| PLO12 | Yetkinlikler - Öğrenme Yetkinliği | To organize laboratory courses of Medical Biology and Genetics courses at undergraduate level | 1 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Gene structure | Slide preparation | |
| 2 | Active genes, evolution of genes with introns | Slide preparation | |
| 3 | Active genes, evolution of genes with introns | Slide preparation | |
| 4 | Evolution and Exons, Domain | Slide preparation | |
| 5 | Species complexity and Gene number | Slide preparation | |
| 6 | Essential gene number and its importance | Slide preparation | |
| 7 | Essential gene number and its importance | Slide preparation | |
| 8 | Mid-Term Exam | Preparation of multiple-choice questions | |
| 9 | The relationship between protein size and genome and complexity | Slide preparation | |
| 10 | Genome structure, genome | Slide preparation | |
| 11 | Transcriptome, proteom and protein protein interaction concepts | Slide preparation | |
| 12 | Genomic size, human genome, genomics and proteomics | Slide preparation | |
| 13 | Protein properties and proteomics, Why Proteom | Slide preparation | |
| 14 | The relationship between homology and protein structure and function | Slide preparation | |
| 15 | Applications in proteomics and medicine, proteome studies and stages, proteome techniques | Slide preparation | |
| 16 | Term Exams | Preparation of multiple-choice questions | |
| 17 | Term Exams | Preparation of multiple-choice questions |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 3 | 42 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 3 | 42 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 3 | 12 | 36 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 3 | 3 |
| Final Exam | 1 | 3 | 3 |
| Total Workload (Hour) | 126 | ||
| Total Workload / 25 (h) | 5,04 | ||
| ECTS | 5 ECTS | ||