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Information
| Code | BY725 |
| Name | Mitochondrial DNA Demages and Its Pathogenesis |
| Term | 2023-2024 Academic Year |
| Term | Fall |
| Duration (T+A) | 3-0 (T-A) (17 Week) |
| ECTS | 6 ECTS |
| National Credit | 3 National Credit |
| Teaching Language | Türkçe |
| Level | Yüksek Lisans Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Prof. Dr. HASAN BASRİ İLA |
| Course Instructor |
1 |
Course Goal / Objective
The aim of this course is to teach the mitochondria genome and detailed information about the disruptions that may occur in this genome.
Course Content
Diseases related to mitochondrial dysfunction
Course Precondition
None
Resources
Lecture Notes
Notes
Lecture Notes
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Explain the structure of mitochondria in detail |
| LO02 | List the information about mitochondrial DNA |
| LO03 | Evaluate similarities about mitochondrial diseases |
| LO04 | Has knowledge of the maternal origin of mitochondrial inheritance |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Based on the undergraduate level qualifications, develops and deepens the knowledge in the same or different field at the level of expertise and analyzes and interprets them using statistical methods. | 4 |
| PLO02 | Bilgi - Kuramsal, Olgusal | Identifies the interdisciplinary interaction that the field is related to. | 3 |
| PLO03 | Bilgi - Kuramsal, Olgusal | Interprets the knowledge gained in the field by integrating the information from different disciplines and creates new information. | |
| PLO04 | Bilgi - Kuramsal, Olgusal | Carries out a study that requires expertise related to the field independently. | 5 |
| PLO05 | Beceriler - Bilişsel, Uygulamalı | Evaluates the knowledge and skills acquired at the level of expertise in the field with a critical approach and directs its learning. | 4 |
| PLO06 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Supports the current developments in the field and their studies with quantitative and qualitative data and transmits them both in the field and outside the field systematically in written, oral and visual form. | |
| PLO07 | Yetkinlikler - Öğrenme Yetkinliği | It supervises the social, scientific, cultural and ethical values in the collection, interpretation, application and announcement stages of the data related to the field and teaches these values. | 3 |
| PLO08 | Bilgi - Kuramsal, Olgusal | The information they absorbed in the field; use problem solving and / or practical skills in interdisciplinary studies. | 4 |
| PLO09 | Belirsiz | It contributes to the solution of social, scientific, cultural and ethical problems encountered in the field and supports the development of these values. | |
| PLO10 | Belirsiz | Develops new ideas and methods related to the field by using high level mental processes such as creative and critical thinking, problem solving and decision making. |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Mitochondria and mtDNA structure | Scanning and reading different sources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 2 | Maternal inheritance of mtDNA | Scanning and reading different sources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 3 | Reactive oxygen species and production mechanism | Scanning and reading different sources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 4 | Stimulation of antioxidant system | Scanning and reading different sources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 5 | Frequencies, causes and types of mutations in mtDNA | Scanning and reading different sources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 6 | Illness due to mtDNA mutation | Scanning and reading different sources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 7 | Syndromes due to mutation | Scanning and reading different sources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 8 | Mid-Term Exam | An overview | Ölçme Yöntemleri: Sözlü Sınav |
| 9 | The relationship between mitochondria and diabetes | Scanning and reading different sources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 10 | The relationship between mitochondria and parkinson | Scanning and reading different sources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 11 | The relationship between mitochondria and alzheimer | Scanning and reading different sources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 12 | The use of mitochondrial DNA in forensic | Scanning and reading different sources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 13 | Mitochondrial cancer relationship | Scanning and reading different sources | Öğretim Yöntemleri: Tartışma, Grup Çalışması, Bireysel Çalışma |
| 14 | Isolation of mtDNA | Scanning and reading different sources | Öğretim Yöntemleri: Grup Çalışması, Bireysel Çalışma, Proje Temelli Öğrenme |
| 15 | mtDNA identity | Scanning and reading different sources | Öğretim Yöntemleri: Tartışma, Grup Çalışması, Bireysel Çalışma |
| 16 | Term Exams | An overview | Ölçme Yöntemleri: Yazılı Sınav, Ödev |
| 17 | Term Exams | An overview | Ölçme Yöntemleri: Yazılı Sınav, Ödev |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 3 | 42 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 5 | 70 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 15 | 15 |
| Final Exam | 1 | 30 | 30 |
| Total Workload (Hour) | 157 | ||
| Total Workload / 25 (h) | 6,28 | ||
| ECTS | 6 ECTS | ||