TÜRKÇE
ENGLISH
Information
| Code | ECS503 |
| Name | Research Techniques in Pharmacology and Clinical Research |
| Term | 2023-2024 Academic Year |
| Semester | 9. Semester |
| Duration (T+A) | 1-1 (T-A) (17 Week) |
| ECTS | 3 ECTS |
| National Credit | 1 National Credit |
| Teaching Language | Türkçe |
| Level | Lisans Dersi |
| Type | Uygulamalı Ders |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Doç. Dr. FATMA AYDINOĞLU |
| Course Instructor |
Doç. Dr. FATMA AYDINOĞLU
(A Group)
(Ins. in Charge)
Doç. Dr. HACER SİNEM BÜYÜKNACAR (A Group) (Asst. Ins.) |
Course Goal / Objective
It is aimed to explain preclinical studies in pharmacological studies, experimental animal models used in preclinical studies and clinical studies and to use their knowledge about planning, conducting and evaluating experimental/clinical studies.
Course Content
Research areas in pharmacology, preclinicals studies, experimental animal models, basic principles of experimental research, phases of clinical studies, basic principles clinical research,
Course Precondition
None
Resources
Goodman and Gilman's The Pharmacological Basis of Therapeutics
Notes
pubmed and other databases.
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Describe to research areasin pharmacology |
| LO02 | Describe to pre -clinical experimental methods |
| LO03 | Discuss the basic principles of pre-clinical research methods. |
| LO04 | Determine to the suitable method for in vitro and in vivo research project. |
| LO05 | Describe to experimental animal models. |
| LO06 | Explain and use to planing, performing and evaluating of experimental studies. |
| LO07 | Describe and eexplain to the phases of clinical researchs. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Have sufficient knowledge in pharmaceutical field and develop the knowledge. | 4 |
| PLO02 | Bilgi - Kuramsal, Olgusal | Comprehends professional knowledge with ethical responsibility through current laws and legislation. | 1 |
| PLO03 | Beceriler - Bilişsel, Uygulamalı | Provides consultancy service to patients, community and health care personnel and evaluates advanced knowledge and skills with a critical approach. | |
| PLO04 | Beceriler - Bilişsel, Uygulamalı | Possessing the knowledge of historical and current developments in the field of Pharmacy, monitoring, evaluation and application of scientific and evidence-based data, and adopting lifelong learning. | 5 |
| PLO05 | Beceriler - Bilişsel, Uygulamalı | Have the knowledge and skills to help provide patient-oriented pharmacy applications and individualized pharmaceutical care by learning the basics of Clinical Pharmacy, | |
| PLO06 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Takes a role in the evaluation and analysis of the events and cases related to the development of pharmacy profession and education. | 5 |
| PLO07 | Yetkinlikler - Öğrenme Yetkinliği | Integrates and develops professional knowledge via different disciplines and uses the acquired knowledge to improve the health level and quality of life of the community. | 5 |
| PLO08 | Yetkinlikler - Öğrenme Yetkinliği | Use effectively the concepts and applications of basic sciences and basic medical sciences in the field of medicine and pharmacy and update the information. | 5 |
| PLO09 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Communicates effectively in writing and speaking. | 4 |
| PLO10 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Practices the profession in accordance with Atatürk's principles and reforms, equipped with universal knowledge, uses Turkish correctly and knows at least one foreign language. | 4 |
| PLO11 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Be an example to society withexternal appearance, demeanor, attitude and behavior for the other professionals and society and with professional identity | 3 |
| PLO12 | Yetkinlikler - Alana Özgü Yetkinlik | Have knowledge about health policies and health economics, pharmacy management and define the problems in pharmaceutical field. | |
| PLO13 | Yetkinlikler - Alana Özgü Yetkinlik | Interprets information about current health and treatment problems and attends meeting on related matters . Plays an active role in community health. | 5 |
| PLO14 | Yetkinlikler - Alana Özgü Yetkinlik | Acquires basic information about diseases, makes decisions about the drugs used in treatment in accordance with rational drug use. |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Research areas in pharmacology | Reviews relevant book and literature | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 2 | The ethical principles of experimenta lanimal stuides | Reviewsrelevant bookand literature | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 3 | In vitro studies: organ bath studies | Reviews relevant book and literature | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Alıştırma ve Uygulama, Deney / Laboratuvar |
| 4 | Organ bath studies with several tissues | Reviews relevant book and literature | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Alıştırma ve Uygulama, Deney / Laboratuvar |
| 5 | Planning, perfoming and evaluating in vitro studies | Reviews relevant book and literature | Öğretim Yöntemleri: Beyin Fırtınası, Örnek Olay |
| 6 | In vivo studies: Methods used in Analgesics Investigations | Reviews relevant book and literature | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Deney / Laboratuvar |
| 7 | In vivo studies: Methods Used in Antidepressant Drug Research | Reviews relevant book and literature | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Deney / Laboratuvar |
| 8 | Mid-Term Exam | The presentations should be review | Ölçme Yöntemleri: Yazılı Sınav, Ödev, Performans Değerlendirmesi |
| 9 | Planning, perfoming and evaluating in vivo studies | Reviews relevant book and literature | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 10 | Experimentalanimal models in pharmacological studies: Hipertansiyon ve Diyabet | Reviews relevant book and literature | Öğretim Yöntemleri: Anlatım |
| 11 | Experimental animal models used in pharmacology studies: Parkinson, Depression and Schizophrenia | Reviews relevant book and literature | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 12 | The ethical principles of clinical drug researches | Reviews relevant book and literature | Öğretim Yöntemleri: Anlatım |
| 13 | Clinical investigations and phase studies | Reviews relevant book and literature | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 14 | The basic principles of clinical research | Reviews relevant book and literature | Öğretim Yöntemleri: Anlatım |
| 15 | The methods of data evaluation in pharmacological studies | Reviews relevant book and literature | Öğretim Yöntemleri: Soru-Cevap, Örnek Olay |
| 16 | Term Exams | Presentations should be review | Ölçme Yöntemleri: Yazılı Sınav |
| 17 | Term Exams | Presentations should be review | Ölçme Yöntemleri: Yazılı Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 2 | 28 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 2 | 28 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 1 | 2 | 2 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 6 | 6 |
| Final Exam | 1 | 16 | 16 |
| Total Workload (Hour) | 80 | ||
| Total Workload / 25 (h) | 3,20 | ||
| ECTS | 3 ECTS | ||