BT0088 Transgenic Animal Technology and in vivo Modeling

6 ECTS - 3-2 Duration (T+A)- . Semester- 4 National Credit

Information

Code BT0088
Name Transgenic Animal Technology and in vivo Modeling
Term 2023-2024 Academic Year
Term Spring
Duration (T+A) 3-2 (T-A) (17 Week)
ECTS 6 ECTS
National Credit 4 National Credit
Teaching Language Türkçe
Level Doktora Dersi
Type Normal
Mode of study Yüz Yüze Öğretim
Catalog Information Coordinator
Course Instructor
1


Course Goal / Objective

It is aimed to teach transgenic animal technologies, methods of obtaining transgenic animals and in vivo modeling for experimental studies.

Course Content

Transgenic animal production, products and technologies, embryology, superovulation, intracytoplasmic sperm injection, microinjection, somatic cell transfer (cloning), retrovirus mediated gene transfer, embryonic stem cell mediated gene transfer, next generation gene editing tools and their uses, transgenic animal by research topic design (selection of bovine, ovine, poultry, laboratory animals).

Course Precondition

None

Resources

1) Transgenic Animal Technology, Elsevier (2014). 2) Genetic engineering in livestock: New applications and interdisciplinary perspectives, Springer-verlag Heidelberg. (2009) 3) Transgenic Animals in Agriculture, CABI. (1994) and related literature

Notes

1) Transgenic Animal Technology, Elsevier (2014). 2) Genetic engineering in livestock: New applications and interdisciplinary perspectives, Springer-verlag Heidelberg. (2009) 3) Transgenic Animals in Agriculture, CABI. (1994) and related literature


Course Learning Outcomes

Order Course Learning Outcomes
LO01 Learns the technologies of obtaining transgenic animals.
LO02 Learns assisted reproductive techniques in experimental animals.
LO03 Learn to create specific animal models using genetic engineering tools.
LO04 Learns ethical issues on experimental animal usage
LO05 Learns and applicates animal welfare and 3R principles on animal experimentation


Relation with Program Learning Outcome

Order Type Program Learning Outcomes Level
PLO01 Bilgi - Kuramsal, Olgusal Develop and deepen the current and advanced knowledge in the field with original thought and / or research at the level of expertise based on the qualifications of the graduate and reach the original definitions that will bring innovation to the field. 5
PLO02 Bilgi - Kuramsal, Olgusal Understands the interdisciplinary interaction of the field; it achieves original results using knowledge requiring expertise in analysis, synthesis and evaluation of new and complex ideas. 3
PLO03 Beceriler - Bilişsel, Uygulamalı Evaluates, uses and transfers new information in the field with a systematic approach. 5
PLO04 Beceriler - Bilişsel, Uygulamalı Makes critical analysis, synthesis and evaluation of new and complex thoughts. 3
PLO05 Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği Makes leadership in environments that require the analysis of original and interdisciplinary problems. 4
PLO06 Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği It extends the limits of knowledge in its field by publishing at least one scientific article in its field in national and / or international refereed journals and / or producing or interpreting an original work. 2
PLO07 Yetkinlikler - Öğrenme Yetkinliği Develops new ideas and methods related to the field by using high level mental processes such as creative and critical thinking, problem solving and decision making. 4
PLO08 Yetkinlikler - İletişim ve Sosyal Yetkinlik He / she defends his / her original opinions in discussing the subjects in his / her field and establishes an effective communication showing his / her competence in the field.
PLO09 Yetkinlikler - Alana Özgü Yetkinlik Conducts scientific research in national and international scientific research groups.
PLO10 Yetkinlikler - Alana Özgü Yetkinlik Establishes functional interaction by using strategic decision making processes in solving problems encountered in the field. 5


Week Plan

Week Topic Preparation Methods
1 Introduction to transgenic animal models Related resources, lecture notes, and literature Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
2 Application areas of transgenic animals Related resources, lecture notes, and literature Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma, Grup Çalışması
3 Gene transfer techniques used in the production of transgenic animals Related resources, lecture notes, and literature Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
4 Control of estrus and superovulation Related resources, lecture notes, and literature Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
5 Assisted reproductive techniques Related resources, lecture notes, and literature Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
6 Genetic replication and its importance in animal production Related resources, lecture notes, and literature Öğretim Yöntemleri:
Soru-Cevap, Anlatım, Tartışma
7 artificial insemination; advantages and disadvantages Related resources, lecture notes, and literature Öğretim Yöntemleri:
Anlatım, Tartışma, Soru-Cevap
8 Gene transfers (Micro-injection, use of embryonic stem cells, retroviral vectors, other gene transfer methods) Related resources, lecture notes, and literature Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
9 Gene transmissions (establishment of transgenic lines, breeding programs with transgenic animals) Related resources, lecture notes, and literature Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
10 Mouse / mice (disease models) Related resources, lecture notes, and literature Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
11 Rats (disease models) Related resources, lecture notes, and literature Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
12 Transgenic applications in farm / large animals Related resources, lecture notes, and literature Öğretim Yöntemleri:
Soru-Cevap, Anlatım, Tartışma
13 Applications in farm / large animals Related resources, lecture notes, and literature Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
14 Transgenic applications in poultry Related resources, lecture notes, and literature Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
15 Transgenic applications in aquaculture animals Related resources, lecture notes, and literature Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
16 Transgenic organisms and ethics Related resources, lecture notes, and literature Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
17 Term Exams Ölçme Yöntemleri:
Yazılı Sınav, Sözlü Sınav, Proje / Tasarım, Ödev


Student Workload - ECTS

Works Number Time (Hour) Workload (Hour)
Course Related Works
Class Time (Exam weeks are excluded) 14 5 70
Out of Class Study (Preliminary Work, Practice) 14 5 70
Assesment Related Works
Homeworks, Projects, Others 0 0 0
Mid-term Exams (Written, Oral, etc.) 1 5 5
Final Exam 1 15 15
Total Workload (Hour) 160
Total Workload / 25 (h) 6,40
ECTS 6 ECTS

Update Time: 10.05.2023 04:01