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Information
| Code | DM0015 |
| Name | Introduction to Stem Cell Biology |
| Term | 2023-2024 Academic Year |
| Term | Fall |
| Duration (T+A) | 3-0 (T-A) (17 Week) |
| ECTS | 6 ECTS |
| National Credit | 3 National Credit |
| Teaching Language | Türkçe |
| Level | Yüksek Lisans Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | |
| Course Instructor |
1 |
Course Goal / Objective
This course aims to provide a basic understanding of comprehensive information about the different biological properties of stem cells.
Course Content
Introduction and definitions, Developmental hierarchy in cells A brief overview of molecular cell biology Basic properties of stem cell Stem cell niche The life cycle of stem cells, stress, and aging.
Course Precondition
None
Resources
Lecture Notes
Notes
Stem Cell (Biology, Types and Use in Treatment) Alp CAN
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Learn about molecular biology. |
| LO02 | Have knowledge about the basic properties of stem cells. |
| LO03 | Cell division is learned. |
| LO04 | Intracellular membrane and cell receptors will be learned. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Yetkinlikler - Alana Özgü Yetkinlik | Having advanced knowledge of the concepts, theories and principles of the Tissue Engineering Department | 4 |
| PLO02 | Yetkinlikler - Alana Özgü Yetkinlik | Being equipped with advanced mathematics, science and engineering knowledge | |
| PLO03 | Yetkinlikler - Alana Özgü Yetkinlik | To be able to design and perform advanced experiments in the Tissue Engineering Department; To be able to analyze and interpret the results and the data obtained. | 3 |
| PLO04 | Yetkinlikler - Alana Özgü Yetkinlik | Be equipped with a variety of advanced engineering techniques and skills | |
| PLO05 | Yetkinlikler - Alana Özgü Yetkinlik | Ability to lead the definition, design, development and deployment of a product or production method | 3 |
| PLO06 | Yetkinlikler - Alana Özgü Yetkinlik | Being aware of the necessity of lifelong learning and being able to constantly renew oneself | |
| PLO07 | Yetkinlikler - Alana Özgü Yetkinlik | Ability to use English effectively both verbally and in writing on technical or non-technical subjects | |
| PLO08 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Being prone to teamwork, being able to communicate well with the environment; Ability to work efficiently as a member of a multi-faceted and interdisciplinary team | |
| PLO09 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Being curious and innovative, aware of its technical and ethical responsibilities | 3 |
| PLO10 | Yetkinlikler - Alana Özgü Yetkinlik | Gains high-level skills in using research methods in studies related to the field of Tissue Engineering. | 5 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Introduction and definitions | Researching the basic concepts of stem cells from Internet resources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Beyin Fırtınası |
| 2 | Zygote and pre-zygote The process to the blastocyst | Research on the developmental stages of gamete mother cells | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Beyin Fırtınası |
| 3 | Advanced development of ectoderm, mesoderm, and endoderm | Preliminary research on embryonic layers (leaves) | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 4 | Brief overview of molecular cell biology | Researching basic molecular mechanisms (replication, transcription, and translation) | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 5 | Chromosomes, chromatin, histones, centromeres, and telomeres | Reviewing basic genetic information | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 6 | Transcription factors | The topic of transcriptomics will be discussed | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 7 | Genetic code and protein synthesis | Gene expression subject preparation | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 8 | Mid-Term Exam | topic repetition | Ölçme Yöntemleri: Sözlü Sınav, Ödev |
| 9 | Signaling molecules | Intracellular communication | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 10 | Cell membrane and intracellular receptors | Receptor and ligand interaction | Öğretim Yöntemleri: Anlatım, Tartışma |
| 11 | Basic properties of stem cells | Differences between stem cells | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 12 | Stemness, self-renewal, differentiation | Totipotency, pluripotency, and multipotency | Öğretim Yöntemleri: Anlatım, Tartışma, Soru-Cevap |
| 13 | Stem cell niche | Microenvironment interaction of stem cell | Öğretim Yöntemleri: Soru-Cevap, Anlatım, Tartışma |
| 14 | Asymmetric cell division | Cell division dynamics | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 15 | Effects on stem cell aging | Changes in gene expression | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 16 | Term Exams | An overview | Ölçme Yöntemleri: Ödev, Sözlü Sınav |
| 17 | Term Exams | An overwiev | Ölçme Yöntemleri: Ödev, Sözlü Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 3 | 42 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 7 | 98 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 1 | 5 | 5 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 5 | 5 |
| Final Exam | 1 | 5 | 5 |
| Total Workload (Hour) | 155 | ||
| Total Workload / 25 (h) | 6,20 | ||
| ECTS | 6 ECTS | ||