TÜRKÇE
ENGLISH
Information
| Code | ECS318 |
| Name | Standardization and Quality Control Methods in Phytotherapeuticals |
| Term | 2024-2025 Academic Year |
| Semester | 6. Semester |
| Duration (T+A) | 2-0 (T-A) (17 Week) |
| ECTS | 2 ECTS |
| National Credit | 2 National Credit |
| Teaching Language | Türkçe |
| Level | Lisans Dersi |
| Type | Normal |
| Label | E Elective |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Dr. Öğr. Üyesi TUBA ŞERBETÇİ |
| Course Instructor |
Arş.Gör.Dr. Seçil KARAHÜSEYİN
(A Group)
(Ins. in Charge)
|
Course Goal / Objective
It aims to provide information about the necessity and importance of standardization in herbal products, the use of chromatographic and other special analysis methods from a pharmacist's perspective in standardization and quality control stages.
Course Content
In order to get the desired benefit from the plants, it is necessary to process the right plant correctly and to prepare preparations / products with high efficiency, reliability and quality.
Course Precondition
None.
Resources
WHO Library Cataloguing in Publication Data. Quality control methods for medicinal plant materials, 1998.
Notes
Karahuseyin, S. Lecture Notes, 2022.
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Explain the defiinition of quality for herbal preparations. |
| LO02 | Classify herbal medicines and give examples. |
| LO03 | Explain standardization in phytotherapeuticals |
| LO04 | Explain phytochemical evaluation methods for standardisation |
| LO05 | Array the necessity of standardization |
| LO06 | Explain the importance of good agricultural practice for phytotherapeuticals |
| LO07 | Explain the quality-control methods present in Pharmacopeia |
| LO08 | Give information about herbal monographs |
| LO09 | Explain phytochemical analyses and bioactive component quantification methods |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Have sufficient knowledge in pharmaceutical field and develop the knowledge. | 4 |
| PLO02 | Bilgi - Kuramsal, Olgusal | Comprehends professional knowledge with ethical responsibility through current laws and legislation. | |
| PLO03 | Beceriler - Bilişsel, Uygulamalı | Provides consultancy service to patients, community and health care personnel and evaluates advanced knowledge and skills with a critical approach. | 3 |
| PLO04 | Beceriler - Bilişsel, Uygulamalı | Possessing the knowledge of historical and current developments in the field of Pharmacy, monitoring, evaluation and application of scientific and evidence-based data, and adopting lifelong learning. | 3 |
| PLO05 | Beceriler - Bilişsel, Uygulamalı | Have the knowledge and skills to help provide patient-oriented pharmacy applications and individualized pharmaceutical care by learning the basics of Clinical Pharmacy, | |
| PLO06 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Takes a role in the evaluation and analysis of the events and cases related to the development of pharmacy profession and education. | |
| PLO07 | Yetkinlikler - Öğrenme Yetkinliği | Integrates and develops professional knowledge via different disciplines and uses the acquired knowledge to improve the health level and quality of life of the community. | 2 |
| PLO08 | Yetkinlikler - Öğrenme Yetkinliği | Use effectively the concepts and applications of basic sciences and basic medical sciences in the field of medicine and pharmacy and update the information. | |
| PLO09 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Communicates effectively in writing and speaking. | |
| PLO10 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Practices the profession in accordance with Atatürk's principles and reforms, equipped with universal knowledge, uses Turkish correctly and knows at least one foreign language. | |
| PLO11 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Be an example to society withexternal appearance, demeanor, attitude and behavior for the other professionals and society and with professional identity | |
| PLO12 | Yetkinlikler - Alana Özgü Yetkinlik | Have knowledge about health policies and health economics, pharmacy management and define the problems in pharmaceutical field. | |
| PLO13 | Yetkinlikler - Alana Özgü Yetkinlik | Interprets information about current health and treatment problems and attends meeting on related matters . Plays an active role in community health. | |
| PLO14 | Yetkinlikler - Alana Özgü Yetkinlik | Acquires basic information about diseases, makes decisions about the drugs used in treatment in accordance with rational drug use. |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Introduction to standardisaiton of phytotherapeuticals | Textbooks, current literature on the subject | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 2 | Adulteration/substitution, identity and purity | Textbooks, current literature on the subject | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 3 | Macro and microscopic examination for identification of right variety and search of adulterants. | Textbooks, current literature on the subject | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 4 | Foreign organic matter investigation | Textbooks, current literature on the subject | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 5 | Ash values, criteria to judge the identity and purity of crude drug | Textbooks, current literature on the subject | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 6 | Moisture content | Textbooks, current literature on the subject | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 7 | Extractive values and the effect of different methods to extrative values | Textbooks, current literature on the subject | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 8 | Mid-Term Exam | Subject repetition | Ölçme Yöntemleri: Ödev, Sözlü Sınav, Proje / Tasarım, Performans Değerlendirmesi |
| 9 | Qualitative chemical evaluation of crude drug with respect to phytochemical constituent | Textbooks, current literature on the subject | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 10 | Chromatographic examination: Include identification of crude drug based on the use of major chemical constituents as markers | Textbooks, current literature on the subject | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 11 | Quantitative chemical evaluation: To estimate the amount of the major classes of constituents. | Textbooks, current literature on the subject | Öğretim Yöntemleri: Soru-Cevap, Anlatım, Tartışma |
| 12 | The importance of analytical methods for the quality-control management of herbal drugs | Textbooks, current literature on the subject | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 13 | Other critical factors affecting the quality control of herbal drugs | Textbooks, current literature on the subject | Öğretim Yöntemleri: Soru-Cevap, Anlatım, Tartışma |
| 14 | Microbial contaminants and aflatoxins | Textbooks, current literature on the subject | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 15 | Good agricultural/Manufacturing practices | Textbooks, current literature on the subject | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 16 | Term Exams | Subject repetition | Ölçme Yöntemleri: Yazılı Sınav |
| 17 | Term Exams | Subject repetition | Ölçme Yöntemleri: Yazılı Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 2 | 28 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 1 | 14 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 4 | 4 |
| Final Exam | 1 | 8 | 8 |
| Total Workload (Hour) | 54 | ||
| Total Workload / 25 (h) | 2,16 | ||
| ECTS | 2 ECTS | ||