TÜRKÇE
ENGLISH
Information
| Code | ECS318 |
| Name | Standardization and Quality Control Methods in Phytotherapeuticals |
| Term | 2024-2025 Academic Year |
| Semester | 6. Semester |
| Duration (T+A) | 2-0 (T-A) (17 Week) |
| ECTS | 2 ECTS |
| National Credit | 2 National Credit |
| Teaching Language | Türkçe |
| Level | Lisans Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Dr. Öğr. Üyesi TUBA ŞERBETÇİ |
| Course Instructor |
1 2 |
Course Goal / Objective
Comprehends the necessity and importance of the standardization process in herbal products, and the importance of chromatographic and other special analysis methods from a pharmacist's point of view.
Course Content
In order to get the desired benefit from the plants, it is necessary to process the right plant correctly and to prepare preparations / products with high efficiency, reliability and quality.
Course Precondition
none
Resources
Efficacy, safety, quality control, marketing and regulatory guidelines for herbal medicines (phytotherapeutic agents) Braz J Med Biol Res . 2000 Feb Phytotherapy and quality of herbal medicines, Fitoterapia, 2000 World Health Organization. (2011). Quality control methods for herbal materials. World Health Organization. https://apps.who.int/iris/handle/10665/44479 ders notları documents provided by lecturer
Notes
articles from literature
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Explain the defiinition of quality for herbal preparations. |
| LO02 | Give information about fferent formulations of phytotherapeuticals |
| LO03 | Classify herbal medicines and give examples. |
| LO04 | Explain standardization in phytotherapeuticals |
| LO05 | Explain phytochemical evaluation methods for standardisation |
| LO06 | Array the necessity of standardization |
| LO07 | Explain the importance of good agricultural practice for phytotherapeuticals |
| LO08 | Give information about the chromatographic techniques |
| LO09 | Explain the quality-control methods present in Pharmacopeia |
| LO10 | Give information about herbal monographs |
| LO11 | Explain ash values quantification methods |
| LO12 | Explain lost in drying methods |
| LO13 | Explain the importance of heavy metals analyses |
| LO14 | Explain the importance of microscopical examination |
| LO15 | Explain phytochemical analyses and bioactive component quantification methods |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Have sufficient knowledge in pharmaceutical field and develop the knowledge. | 4 |
| PLO02 | Bilgi - Kuramsal, Olgusal | Comprehends professional knowledge with ethical responsibility through current laws and legislation. | |
| PLO03 | Beceriler - Bilişsel, Uygulamalı | Provides consultancy service to patients, community and health care personnel and evaluates advanced knowledge and skills with a critical approach. | 3 |
| PLO04 | Beceriler - Bilişsel, Uygulamalı | Possessing the knowledge of historical and current developments in the field of Pharmacy, monitoring, evaluation and application of scientific and evidence-based data, and adopting lifelong learning. | 3 |
| PLO05 | Beceriler - Bilişsel, Uygulamalı | Have the knowledge and skills to help provide patient-oriented pharmacy applications and individualized pharmaceutical care by learning the basics of Clinical Pharmacy, | |
| PLO06 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Takes a role in the evaluation and analysis of the events and cases related to the development of pharmacy profession and education. | 3 |
| PLO07 | Yetkinlikler - Öğrenme Yetkinliği | Integrates and develops professional knowledge via different disciplines and uses the acquired knowledge to improve the health level and quality of life of the community. | 2 |
| PLO08 | Yetkinlikler - Öğrenme Yetkinliği | Use effectively the concepts and applications of basic sciences and basic medical sciences in the field of medicine and pharmacy and update the information. | 2 |
| PLO09 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Communicates effectively in writing and speaking. | 2 |
| PLO10 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Practices the profession in accordance with Atatürk's principles and reforms, equipped with universal knowledge, uses Turkish correctly and knows at least one foreign language. | |
| PLO11 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Be an example to society withexternal appearance, demeanor, attitude and behavior for the other professionals and society and with professional identity | 3 |
| PLO12 | Yetkinlikler - Alana Özgü Yetkinlik | Have knowledge about health policies and health economics, pharmacy management and define the problems in pharmaceutical field. | 3 |
| PLO13 | Yetkinlikler - Alana Özgü Yetkinlik | Interprets information about current health and treatment problems and attends meeting on related matters . Plays an active role in community health. | |
| PLO14 | Yetkinlikler - Alana Özgü Yetkinlik | Acquires basic information about diseases, makes decisions about the drugs used in treatment in accordance with rational drug use. | 3 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Introduction to standardisaiton of phytotherapeuticals | Textbooks, current literature on the subject | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 2 | Adulteration/substitution, identity and purity | Textbooks, current literature on the subject | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 3 | Macro and microscopic examination for identification of right variety and search of adulterants. | Textbooks, current literature on the subject | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 4 | Foreign organic matter investigation | Textbooks, current literature on the subject | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 5 | Ash values, criteria to judge the identity and purity of crude drug | Textbooks, current literature on the subject | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 6 | Moisture content | Textbooks, current literature on the subject | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 7 | Extractive values and the effect of different methods to extrative values | Textbooks, current literature on the subject | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 8 | Mid-Term Exam | Subject repetition | Ölçme Yöntemleri: Ödev, Sözlü Sınav, Proje / Tasarım, Performans Değerlendirmesi |
| 9 | Qualitative chemical evaluation of crude drug with respect to phytochemical constituent | Textbooks, current literature on the subject | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 10 | Chromatographic examination: Include identification of crude drug based on the use of major chemical constituents as markers | Textbooks, current literature on the subject | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 11 | Quantitative chemical evaluation: To estimate the amount of the major classes of constituents. | Textbooks, current literature on the subject | Öğretim Yöntemleri: Soru-Cevap, Anlatım, Tartışma |
| 12 | The importance of analytical methods for the quality-control management of herbal drugs | Textbooks, current literature on the subject | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 13 | Other critical factors affecting the quality control of herbal drugs | Textbooks, current literature on the subject | Öğretim Yöntemleri: Soru-Cevap, Anlatım, Tartışma |
| 14 | Microbial contaminants and aflatoxins | Textbooks, current literature on the subject | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 15 | Good agricultural/Manufacturing practices | Textbooks, current literature on the subject | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 16 | Term Exams | Subject repetition | Ölçme Yöntemleri: Yazılı Sınav |
| 17 | Term Exams | Subject repetition | Ölçme Yöntemleri: Yazılı Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 2 | 28 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 1 | 14 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 4 | 4 |
| Final Exam | 1 | 8 | 8 |
| Total Workload (Hour) | 54 | ||
| Total Workload / 25 (h) | 2,16 | ||
| ECTS | 2 ECTS | ||