TÜRKÇE
ENGLISH
Information
| Code | ECS527 |
| Name | Enzymology |
| Term | 2024-2025 Academic Year |
| Semester | 9. Semester |
| Duration (T+A) | 2-0 (T-A) (17 Week) |
| ECTS | 3 ECTS |
| National Credit | 2 National Credit |
| Teaching Language | Türkçe |
| Level | Lisans Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Doç. Dr. ÖZLEM ALPTEKİN |
| Course Instructor |
Doç. Dr. ÖZLEM ALPTEKİN
(A Group)
(Ins. in Charge)
|
Course Goal / Objective
Students learn basic approaches about the role of enzymes in therapy and drug design by understanding the fundamental issues of enzymology,
Course Content
Students are given information about the mechanisms of action of enzymes, kinetics, artificial enzymes and enzyme molecules, enzyme production and purification, production of industrial enzymes with gene technology, immobilized enzymes, industrial applications of enzymes, enzymes used in treatment and drug design, and enzymes used in organic synthesis in this course.
Course Precondition
There is no prerequisite.
Resources
Devasena T, Enzymology, Oxford press, 2010
Notes
Guisan, J. M. Immobilization of Enzymes and Cells Humana Press 2013 ISBN 978-1-62703-550-7
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | He/She explains the basic studies in the field of enzymology. |
| LO02 | He/She explain the industrial applications of enzymes alone. |
| LO03 | She/He knows enzymes used in treatment and drug design. |
| LO04 | She/He gives examples of the use of immobilized enzymes for diagnosis and treatment. |
| LO05 | She/He explains the basic components of biosensors. |
| LO06 | She/He gives examples of the use of biosensors for diagnostic purposes. |
| LO07 | She/He gives examples of enzymes used in drug synthesis. |
| LO08 | She/He has the ability to conduct an advanced research, educate and direct the society in the field of health. |
| LO09 | He/She is competent in lifelong learning, self-renewal and development of pharmaceutical services. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Have sufficient knowledge in pharmaceutical field and develop the knowledge. | 2 |
| PLO02 | Bilgi - Kuramsal, Olgusal | Comprehends professional knowledge with ethical responsibility through current laws and legislation. | |
| PLO03 | Beceriler - Bilişsel, Uygulamalı | Provides consultancy service to patients, community and health care personnel and evaluates advanced knowledge and skills with a critical approach. | |
| PLO04 | Beceriler - Bilişsel, Uygulamalı | Possessing the knowledge of historical and current developments in the field of Pharmacy, monitoring, evaluation and application of scientific and evidence-based data, and adopting lifelong learning. | |
| PLO05 | Beceriler - Bilişsel, Uygulamalı | Have the knowledge and skills to help provide patient-oriented pharmacy applications and individualized pharmaceutical care by learning the basics of Clinical Pharmacy, | |
| PLO06 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Takes a role in the evaluation and analysis of the events and cases related to the development of pharmacy profession and education. | 2 |
| PLO07 | Yetkinlikler - Öğrenme Yetkinliği | Integrates and develops professional knowledge via different disciplines and uses the acquired knowledge to improve the health level and quality of life of the community. | |
| PLO08 | Yetkinlikler - Öğrenme Yetkinliği | Use effectively the concepts and applications of basic sciences and basic medical sciences in the field of medicine and pharmacy and update the information. | 4 |
| PLO09 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Communicates effectively in writing and speaking. | |
| PLO10 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Practices the profession in accordance with Atatürk's principles and reforms, equipped with universal knowledge, uses Turkish correctly and knows at least one foreign language. | |
| PLO11 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Be an example to society withexternal appearance, demeanor, attitude and behavior for the other professionals and society and with professional identity | |
| PLO12 | Yetkinlikler - Alana Özgü Yetkinlik | Have knowledge about health policies and health economics, pharmacy management and define the problems in pharmaceutical field. | |
| PLO13 | Yetkinlikler - Alana Özgü Yetkinlik | Interprets information about current health and treatment problems and attends meeting on related matters . Plays an active role in community health. | 2 |
| PLO14 | Yetkinlikler - Alana Özgü Yetkinlik | Acquires basic information about diseases, makes decisions about the drugs used in treatment in accordance with rational drug use. |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | An overview of enzymology. | Reading the relevant part of the textbook. | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Beyin Fırtınası |
| 2 | Fundamental principles of enzymology | Reading the relevant part of the textbook. | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 3 | The mechanism of action of enzymes and determination of active centers. | Reading the relevant part of the textbook. | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 4 | Enzyme kinetics. | Reading the relevant part of the textbook. | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Problem Çözme |
| 5 | Modeling of enzymatic catalysis. | Reading the relevant part of the textbook. | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 6 | Artificial enzymes and enzyme models. | Reading the relevant part of the textbook. | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 7 | Enzyme production and purification. | Reading the relevant part of the textbook. | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 8 | Mid-Term Exam | Re-studying the topics covered in the course from the relevant textbooks and lecture notes. | Ölçme Yöntemleri: Yazılı Sınav |
| 9 | Production of industrial enzymes with gene technology. | Reading the relevant part of the textbook. | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 10 | Immobilized enzymes. | Reading the relevant part of the textbook. | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 11 | Industrial applications of enzymes. | Reading the relevant part of the textbook. | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 12 | Enzymes in treatment and drug design. | Reading the relevant part of the textbook. | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 13 | Enzymes in genetic engineering. | Reading the relevant part of the textbook. | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 14 | Biosensors. | Reading the relevant part of the textbook. | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 15 | Enzymes in organic synthesis. | Reading the relevant part of the textbook. | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 16 | Term Exams | Re-studying the topics covered in the course from the relevant textbooks and lecture notes. | Ölçme Yöntemleri: Yazılı Sınav, Ödev |
| 17 | Term Exams | Re-studying the topics covered in the course from the relevant textbooks and lecture notes. | Ölçme Yöntemleri: Yazılı Sınav, Ödev |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 2 | 28 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 2 | 28 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 6 | 6 |
| Final Exam | 1 | 16 | 16 |
| Total Workload (Hour) | 78 | ||
| Total Workload / 25 (h) | 3,12 | ||
| ECTS | 3 ECTS | ||