TÜRKÇE
ENGLISH
Information
| Code | VFT518 |
| Name | Pharmacology andin toxicology Laboratory Techniques and Applications |
| Term | 2024-2025 Academic Year |
| Term | Fall and Spring |
| Duration (T+A) | 1-2 (T-A) (17 Week) |
| ECTS | 6 ECTS |
| National Credit | 3 National Credit |
| Teaching Language | Türkçe |
| Level | Yüksek Lisans Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | |
| Course Instructor |
Prof. Dr. PETEK PİNER BENLİ
(A Group)
(Ins. in Charge)
|
Course Goal / Objective
The aim of this course is to teach the analysis (pesticide, mycotoxin, metal, drug) methods and techniques used in the pharmacology and toxicology laboratory, the working principles of devices (HPLC, TLC, GC spectrophotometer, centrifuge, etc.), the basic rules.
Course Content
Basic laboratory rules, chemicals used in the laboratory, chemical safety and risks, basic instruments, analysis methods performed in the Pharmacology and Toxicology laboratory, Toxicological sample examination and preparation methods, HPLC, TLC, GC, spectrophotometer, centrifuge, ELISA.
Course Precondition
There is no prerequisite for this course.
Resources
Daglos A Skoog. Enstrümental Analiz, 2018.
Notes
Daglos A Skoog. Enstrümental Analiz, 2018.
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Explains the basic rules in the laboratory. |
| LO02 | Explain the chemicals used in the laboratory, their chemical safety and risks, in their own words. |
| LO03 | Explains the basic instruments used in the laboratory and their working principles. |
| LO04 | Can manage and apply the analyzes carried out in the Pharmacology and Toxicology laboratory. |
| LO05 | Applies toxicological sample examination and preparation methods. |
| LO06 | Can use instruments and equipments such as HPLC, TLC, GC, spectrophotometer, centrifuge etc. for pharmacological and toxicological analysis. |
| LO07 | Explain how the ELISA method is applied and apply ELISA method. |
| LO08 | Determines and uses databases that will increase his professional knowledge on the subject. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Explains the sources, properties, and effects of drugs, the situations in which they are used and not used, their movements in the body, their interactions with other drugs, and the conditions of use in livestock animals. | |
| PLO02 | Bilgi - Kuramsal, Olgusal | Explains the properties of toxic substances, their sources, toxicity, movements in the body, modes of action, effects, methods of diagnosis, treatment, and protection. | |
| PLO03 | Bilgi - Kuramsal, Olgusal | Explains the doses and forms of drugs used in treatment. | |
| PLO04 | Bilgi - Kuramsal, Olgusal | Explains the administration and exposure routes of drugs and poisons and their changes in the animal body. | |
| PLO05 | Bilgi - Kuramsal, Olgusal | Explains the mechanisms of action of drugs and poisons in the body. | |
| PLO06 | Beceriler - Bilişsel, Uygulamalı | Prepares basic drug formulations in the laboratory. | |
| PLO07 | Bilgi - Kuramsal, Olgusal | Explains the analytical methods and devices used in pharmacology and toxicology. | 5 |
| PLO08 | Yetkinlikler - Alana Özgü Yetkinlik | Can report and interpret the results obtained from pharmacological and toxicological analyses | 4 |
| PLO09 | Yetkinlikler - Alana Özgü Yetkinlik | Explains and applies the ethical rules that must be followed with experimental animals and alternative methods used in scientific researches. | |
| PLO10 | Beceriler - Bilişsel, Uygulamalı | Explains the harmful effects of chemical, biological, radiological, and nuclear warfare agents on human, animal, and environmental health and applies protection methods against these agents. | |
| PLO11 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Follows and evaluates current information, methods, and practices related to Veterinary Pharmacology and Toxicology and can use them in the scientific works. | 4 |
| PLO12 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Prepares, publishes, and presents articles using the results of scientific studies in Veterinary Pharmacology and Toxicology. | 4 |
| PLO13 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Can manage and participate in scientific research projects in Veterinary Pharmacology and Toxicology. | |
| PLO14 | Yetkinlikler - Alana Özgü Yetkinlik | Participates in commissions that deal with the identification and solution of problems related to human, animal, and environmental health using the knowledge gained in Veterinary Pharmacology and Toxicology | 4 |
| PLO15 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Can carry out joint research projects with branches of science related to pharmacology and toxicology. | 4 |
| PLO16 | Beceriler - Bilişsel, Uygulamalı | Plans scientific studies based on the priority areas of the Council of Higher Education and the university and sustainable development goals and adopts lifelong learning as a principle. | 3 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Explaining the Importance of the Course, Its Procedure and Evaluation Method to the Student | Review of Books and Lecture Notes | Öğretim Yöntemleri: Anlatım |
| 2 | Basic rules in the laboratory | Review of Books and Lecture Notes | Öğretim Yöntemleri: Anlatım |
| 3 | Basic instruments and lab equipment used in the laboratory | Review of Books and Lecture Notes | Öğretim Yöntemleri: Anlatım |
| 4 | Cleaning of lab equipment used in laboratory | Review of Books and Lecture Notes | Öğretim Yöntemleri: Anlatım |
| 5 | Laboratory safety Chemical and biological safety | Review of Books and Lecture Notes | Öğretim Yöntemleri: Soru-Cevap |
| 6 | Basic laboratory instruments (centrifuge, spectrophotometer etc.), working principles | Review of Books and Lecture Notes | Öğretim Yöntemleri: Soru-Cevap |
| 7 | Toxicological sample examination methods | Review of Books and Lecture Notes | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 8 | Mid-Term Exam | Review of Books and Lecture Notes | Ölçme Yöntemleri: Sözlü Sınav, Ödev |
| 9 | Thin Layer Chromatography (TLC) | Review of Books and Lecture Notes | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 10 | Sample analysis in Thin Layer Chromatography (TLC) | Review of Books and Lecture Notes | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 11 | High Pressure Liquid Chromatography (HPLC) | Review of Books and Lecture Notes | Öğretim Yöntemleri: Soru-Cevap, Anlatım |
| 12 | Sample analysis in High Pressure Liquid Chromatography (HPLC) | Review of Books and Lecture Notes | Öğretim Yöntemleri: Tartışma, Anlatım |
| 13 | Gas Chromatography (GC) | Review of Books and Lecture Notes | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 14 | Sample analysis in Gas Chromatography (GC) | Review of Books and Lecture Notes | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Alıştırma ve Uygulama |
| 15 | ELISA Method and sample analysis | Review of Books and Lecture Notes | Öğretim Yöntemleri: Tartışma, Soru-Cevap, Anlatım |
| 16 | Term Exams | Review of Books and Lecture Notes | Ölçme Yöntemleri: Sözlü Sınav, Ödev |
| 17 | Term Exams | Review of Books and Lecture Notes | Ölçme Yöntemleri: Ödev, Sözlü Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 15 | 3 | 45 |
| Out of Class Study (Preliminary Work, Practice) | 17 | 2 | 34 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 1 | 48 | 48 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 8 | 8 |
| Final Exam | 1 | 15 | 15 |
| Total Workload (Hour) | 150 | ||
| Total Workload / 25 (h) | 6,00 | ||
| ECTS | 6 ECTS | ||