BT0109 Signal Transmission in Cancer

6 ECTS - 3-0 Duration (T+A)- . Semester- 3 National Credit

Information

Code BT0109
Name Signal Transmission in Cancer
Term 2024-2025 Academic Year
Semester . Semester
Duration (T+A) 3-0 (T-A) (17 Week)
ECTS 6 ECTS
National Credit 3 National Credit
Teaching Language Türkçe
Level Yüksek Lisans Dersi
Type Normal
Mode of study Yüz Yüze Öğretim
Catalog Information Coordinator


Course Goal / Objective

In this course, students understand the mechanism of the cancer cell's biological behavior, the receptors that affect these behaviors, the signals and how the transmission is done.

Course Content

The role of signal transduction in cancer cells at every stage from DNA repair to cell division, and targeting methods of signal transduction pathways in cancer treatments and their use in biotechnology.

Course Precondition

Basic knowledge of Molecular Biology and Genetics

Resources

Textbook of Cell Signaling in Cancer, Yazarlar: Roberts, Jacques Cell Signaling- Principles and Mechanisms. Yazarlar: Wandell Lim, Bruce Mayer, Tony Pawson Cell Signaling Biology – online tool http://www.cellsignallingbiology.co.uk/csb/

Notes

Textbook of Cell Signaling in Cancer, Yazarlar: Roberts, Jacques Cell Signaling- Principles and Mechanisms. Yazarlar: Wandell Lim, Bruce Mayer, Tony Pawson Cell Signaling Biology – online tool http://www.cellsignallingbiology.co.uk/csb/


Course Learning Outcomes

Order Course Learning Outcomes
LO01 Students understand the mechanism of the cancer cell's biological behavior, the receptors, signals, and transmission that influence these behaviors.
LO02 Have information about the role of signal transduction at every stage from DNA repair to cell division.
LO03 Learns the evaluation of scientific research on the subject and the presentation of articles.
LO04 Have information about targeting methods of signal transduction pathways in cancer treatments.


Relation with Program Learning Outcome

Order Type Program Learning Outcomes Level
PLO01 Bilgi - Kuramsal, Olgusal Based on the undergraduate level qualifications, develops and deepens the knowledge in the same or different field at the level of expertise and analyzes and interprets them using statistical methods. 5
PLO02 Beceriler - Bilişsel, Uygulamalı To identifiy the interdisciplinary interaction of the field and to solve use of the methods. 5
PLO03 Beceriler - Bilişsel, Uygulamalı Interpret the knowledge gained in the field by integrating the information from different disciplines and creates new information
PLO04 Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği Develops new strategic approaches for solving complex problems that are encountered in applications related to the field.
PLO05 Yetkinlikler - Öğrenme Yetkinliği To teach the social, scientific, cultural and ethical values during the collection, interpretation, implementation and announcement of the data related to the field.
PLO06 Yetkinlikler - İletişim ve Sosyal Yetkinlik To solve the problems encountered in the field and cominicate by using research methods. 4
PLO07 Yetkinlikler - Alana Özgü Yetkinlik To gain the ability to develop and deepen the knowledge in the field of biotechnology 4
PLO08 Yetkinlikler - Alana Özgü Yetkinlik Establishes functional interaction by using strategic decision-making processes in solving the problems encountered in the field.
PLO09 Yetkinlikler - Öğrenme Yetkinliği Knows the ethical rules to be considered while obtaining biotechnological products.
PLO10 Yetkinlikler - İletişim ve Sosyal Yetkinlik He / she defends his / her original opinions in discussing the subjects in his / her field and establishes an effective communication showing his / her competence in the field.


Week Plan

Week Topic Preparation Methods
1 Introduction to growth factor receptors in cancer with a case, Types of receptors – Research papers Textbook, reading the lecture notes and power point presentation Öğretim Yöntemleri:
Tartışma
2 Ideas and research papers on the working principles of tyrosine kinase family receptors Textbook, reading the lecture notes and power point presentation Öğretim Yöntemleri:
Tartışma
3 Opinions and assignments on signal transduction mechanisms of receptors Textbook, reading the lecture notes and power point presentation Öğretim Yöntemleri:
Soru-Cevap
4 Case-based methods of understanding receptor signal transduction disorders Textbook, reading the lecture notes and power point presentation Öğretim Yöntemleri:
Soru-Cevap
5 Ideas and assignments on targeting the signaling pathway Textbook, reading the lecture notes and power point presentation Öğretim Yöntemleri:
Tartışma
6 In the continuation of the case, ideas on differential diagnosis methods and the methods required for the diagnosis of cancer and determination of research assignments Textbook, reading the lecture notes and power point presentation Ölçme Yöntemleri:
Ödev
7 Discussing the story of a patient who applied with the complaint of Chest Pain – thoughts on which diseases the patient's pain will develop Textbook, reading the lecture notes and power point presentation Öğretim Yöntemleri:
Tartışma
8 Mid- term Textbook, reading the lecture notes and power point presentation Ölçme Yöntemleri:
Performans Değerlendirmesi
9 Opinions on understanding that the patient's disease in the case develops secondary to the disorder of which mechanisms in the cell Textbook, reading the lecture notes and power point presentation Öğretim Yöntemleri:
Tartışma
10 Understanding how carcinogens cause cancer development in Case 1 and research assignments on cancer cell cycle Textbook, reading the lecture notes and power point presentation Öğretim Yöntemleri:
Tartışma
11 Identification of mutations that may disrupt cell cycle control mechanisms in the case and determination of assignments including investigating their differences with normal cells. Textbook, reading the lecture notes and power point presentation Öğretim Yöntemleri:
Tartışma
12 Investigation of cell cycle signaling system based on homework Textbook, reading the lecture notes and power point presentation Öğretim Yöntemleri:
Grup Çalışması
13 Discussions and design assignments on identifying targets to correct patient-detected mutations Textbook, reading the lecture notes and power point presentation Öğretim Yöntemleri:
Soru-Cevap
14 Evaluation of assignments Textbook, homework Ölçme Yöntemleri:
Ödev
15 Article reviews Textbook, reading the lecture notes and power point presentation Öğretim Yöntemleri:
Tartışma
16 Student presentations Textbook, reading the lecture notes and power point presentation Öğretim Yöntemleri:
Bireysel Çalışma
17 Final Exam Textbook, reading the lecture notes and power point presentation Ölçme Yöntemleri:
Performans Değerlendirmesi


Student Workload - ECTS

Works Number Time (Hour) Workload (Hour)
Course Related Works
Class Time (Exam weeks are excluded) 14 3 42
Out of Class Study (Preliminary Work, Practice) 14 4 56
Assesment Related Works
Homeworks, Projects, Others 2 6 12
Mid-term Exams (Written, Oral, etc.) 1 10 10
Final Exam 1 30 30
Total Workload (Hour) 150
Total Workload / 25 (h) 6,00
ECTS 6 ECTS

Update Time: 14.05.2024 04:49