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Information
| Code | BT0060 |
| Name | Molecular Biology of Gene |
| Term | 2024-2025 Academic Year |
| Semester | . Semester |
| Duration (T+A) | 4-0 (T-A) (17 Week) |
| ECTS | 6 ECTS |
| National Credit | 4 National Credit |
| Teaching Language | Türkçe |
| Level | Doktora Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator |
Course Goal / Objective
Detailed examination of basic molecular biology topics
Course Content
Basic structure of DNA, replication, transcription, recombination, function and expression of genes
Course Precondition
No
Resources
PRESENTATION AND LECTURE NOTES PREPARED WITHIN THE CONTENT OF THE COURSE
Notes
Molecular Biology (Prof. Dr. Mehmet Karataş), Gene Cloning and DNA Analysis (T.A. Brown), Methods Used in Molecular Biology (Prof. Dr. Güler Temizkan, Prof. Dr. Nazlı Arda)
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Knows the general structure of DNA and RNA |
| LO02 | Gains knowledge about the Structure and Characteristics of Genes |
| LO03 | Knows and interprets DNA repair mechanisms and replication. |
| LO04 | Gains knowledge of PCR Technology, Gene Cloning strategies, Antisense technology and newly developed gene technologies |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Develop and deepen the current and advanced knowledge in the field with original thought and / or research at the level of expertise based on the qualifications of the graduate and reach the original definitions that will bring innovation to the field. | 2 |
| PLO02 | Bilgi - Kuramsal, Olgusal | Understands the interdisciplinary interaction of the field; it achieves original results using knowledge requiring expertise in analysis, synthesis and evaluation of new and complex ideas. | 2 |
| PLO03 | Beceriler - Bilişsel, Uygulamalı | Evaluates, uses and transfers new information in the field with a systematic approach. | 2 |
| PLO04 | Beceriler - Bilişsel, Uygulamalı | Makes critical analysis, synthesis and evaluation of new and complex thoughts. | 3 |
| PLO05 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Makes leadership in environments that require the analysis of original and interdisciplinary problems. | |
| PLO06 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | It extends the limits of knowledge in its field by publishing at least one scientific article in its field in national and / or international refereed journals and / or producing or interpreting an original work. | 2 |
| PLO07 | Yetkinlikler - Öğrenme Yetkinliği | Develops new ideas and methods related to the field by using high level mental processes such as creative and critical thinking, problem solving and decision making. | 2 |
| PLO08 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | He / she defends his / her original opinions in discussing the subjects in his / her field and establishes an effective communication showing his / her competence in the field. | 2 |
| PLO09 | Yetkinlikler - Alana Özgü Yetkinlik | Conducts scientific research in national and international scientific research groups. | 1 |
| PLO10 | Yetkinlikler - Alana Özgü Yetkinlik | Establishes functional interaction by using strategic decision making processes in solving problems encountered in the field. |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Structure and properties of DNA and nucleic acids | Preparing power point presentations by reading course-related topics and related articles | Öğretim Yöntemleri: Anlatım, Tartışma |
| 2 | Structure and properties of genes | Preparing power point presentations by reading course-related topics and related articles | Öğretim Yöntemleri: Anlatım, Tartışma |
| 3 | DNA replication mechanism | Preparing power point presentations by reading course-related topics and related articles | Öğretim Yöntemleri: Anlatım, Tartışma |
| 4 | DNA repair mechanism | Preparing power point presentations by reading course-related topics and related articles | Öğretim Yöntemleri: Anlatım, Tartışma |
| 5 | Protein Synthesis Transcription mechanism of DNA | Preparing power point presentations by reading course-related topics and related articles | Öğretim Yöntemleri: Anlatım, Tartışma |
| 6 | Protein Synthesis -Translation mechanism | Preparing power point presentations by reading course-related topics and related articles | Öğretim Yöntemleri: Anlatım, Tartışma |
| 7 | Control of eukaryotic gene expression | Preparing power point presentations by reading course-related topics and related articles | Öğretim Yöntemleri: Anlatım, Tartışma |
| 8 | MIDTERM EXAM | Ölçme Yöntemleri: Performans Değerlendirmesi, Sözlü Sınav |
|
| 9 | Control of gene expression in prokaryotes | Preparing power point presentations by reading course-related topics and related articles | Öğretim Yöntemleri: Anlatım, Tartışma |
| 10 | Polymerase Chain Reaction (PCR) | Preparing power point presentations by reading course-related topics and related articles | Öğretim Yöntemleri: Anlatım, Tartışma |
| 11 | cDNA and genomic DNA libraries | Preparing power point presentations by reading course-related topics and related articles | Öğretim Yöntemleri: Anlatım, Tartışma |
| 12 | Gene Cloning | Preparing power point presentations by reading course-related topics and related articles | Öğretim Yöntemleri: Anlatım, Tartışma |
| 13 | Isolation of cloned genes | Preparing power point presentations by reading course-related topics and related articles | Öğretim Yöntemleri: Anlatım, Tartışma |
| 14 | Transposable Elements | Preparing power point presentations by reading course-related topics and related articles | Öğretim Yöntemleri: Anlatım, Tartışma |
| 15 | Antisense RNA technology | Preparing power point presentations by reading course-related topics and related articles | Öğretim Yöntemleri: Anlatım, Tartışma |
| 16 | RNA interferans (RNAi) | Preparing power point presentations by reading course-related topics and related articles | Öğretim Yöntemleri: Anlatım, Tartışma |
| 17 | FINAL EXAM | Ölçme Yöntemleri: Yazılı Sınav, Ödev, Performans Değerlendirmesi |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 4 | 56 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 4 | 56 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 12 | 12 |
| Final Exam | 1 | 28 | 28 |
| Total Workload (Hour) | 152 | ||
| Total Workload / 25 (h) | 6,08 | ||
| ECTS | 6 ECTS | ||