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Information
| Code | BT002 |
| Name | Microbial Biofilms |
| Term | 2024-2025 Academic Year |
| Term | Spring |
| Duration (T+A) | 2-0 (T-A) (17 Week) |
| ECTS | 6 ECTS |
| National Credit | 2 National Credit |
| Teaching Language | Türkçe |
| Level | Belirsiz |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Prof. Dr. IŞIL VAR ÖNGEL |
| Course Instructor |
1 |
Course Goal / Objective
It is aimed to give details about Biofilms, biofilm strategies, biofilms seen in in vivo and in vitro systems,the mechanism of quorum sensing and quorum quenching, biofilm methods (bacteriophages, disinfectants and radiation etc.), biofilms in the industry, the latest developments.
Course Content
Microorganism cells and EPS structures, Biofilm definition, properties, Biofilm forming microorganisms, biofilm strategies, biofilms in in vivo and in vitro systems, quarum sensing and quarum quenching mekanizmaları, struggle methods for biofilm (with bacteriophages, disinfectants and radiation, etc.), biofilms in the industry, recent developments
Course Precondition
none
Resources
Doyle, R. J. (Ed.). (2001). Microbial growth in biofilms, Part B: special environments and physicochemical aspects. Gulf Professional Publishing.
Notes
handouts and slides
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Develops knowledge about microorganism cell and produced metabolites and exopolysaccharide (EPS). |
| LO02 | Learns the definition of biofilm and its contents and strategies |
| LO03 | Recognize and categorize microorganisms capable of biofilm |
| LO04 | Learns the biofilm formation strategies of microorganisms in in vivo and in vitro environments |
| LO05 | Learns the damage caused biofilms formed by microorganisms on the systems and the methods to combat them. |
| LO06 | Learn about the methods used in the fight against biofilm |
| LO07 | Learns the mechanism of Quorum sensing in microorganisms and their role in biofilms |
| LO08 | Have knowledge about Quorum Quenching(QQ) mechanism and strategies of how to prevent biofilm production by QQ |
| LO09 | Have knowledge about the problems of biofilms in industry . Besides, learn about in industry how to use of exopolysaccharide which is in biofilm structure. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Develop and deepen the current and advanced knowledge in the field with original thought and / or research at the level of expertise based on the qualifications of the graduate and reach the original definitions that will bring innovation to the field. | 4 |
| PLO02 | Bilgi - Kuramsal, Olgusal | Understands the interdisciplinary interaction of the field; it achieves original results using knowledge requiring expertise in analysis, synthesis and evaluation of new and complex ideas. | 4 |
| PLO03 | Beceriler - Bilişsel, Uygulamalı | Evaluates, uses and transfers new information in the field with a systematic approach. | |
| PLO04 | Beceriler - Bilişsel, Uygulamalı | Makes critical analysis, synthesis and evaluation of new and complex thoughts. | |
| PLO05 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Makes leadership in environments that require the analysis of original and interdisciplinary problems. | |
| PLO06 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | It extends the limits of knowledge in its field by publishing at least one scientific article in its field in national and / or international refereed journals and / or producing or interpreting an original work. | |
| PLO07 | Yetkinlikler - Öğrenme Yetkinliği | Develops new ideas and methods related to the field by using high level mental processes such as creative and critical thinking, problem solving and decision making. | 4 |
| PLO08 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | He / she defends his / her original opinions in discussing the subjects in his / her field and establishes an effective communication showing his / her competence in the field. | |
| PLO09 | Yetkinlikler - Alana Özgü Yetkinlik | Conducts scientific research in national and international scientific research groups. | |
| PLO10 | Yetkinlikler - Alana Özgü Yetkinlik | Establishes functional interaction by using strategic decision making processes in solving problems encountered in the field. |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | microorganism cell and produced metabolites and exopolysaccharide (EPS) | lecture notes, general microbiology books | Öğretim Yöntemleri: Anlatım |
| 2 | Biofilm definition and content | lecture notes | Öğretim Yöntemleri: Anlatım, Gösteri |
| 3 | Biofilm strategies | lecture notes | Öğretim Yöntemleri: Anlatım |
| 4 | Biofilm-forming microorganisms and pathogens | lecture notes, food microbiology and hygiene books | Öğretim Yöntemleri: Anlatım, Grup Çalışması |
| 5 | Biofilm formation strategies of microorganisms in in vitro conditions | lecture notes, international articles and books | Öğretim Yöntemleri: Anlatım, Bireysel Çalışma |
| 6 | Biofilm formation strategies of microorganisms in in vivo conditions | lecture notes | Öğretim Yöntemleri: Anlatım |
| 7 | the damage caused biofilms formed by microorganisms on the systems and the methods to combat them | lecture notes | Öğretim Yöntemleri: Anlatım |
| 8 | Mid-Term Exam | Ölçme Yöntemleri: Yazılı Sınav |
|
| 9 | the methods used in the fight against biofilm | lecture notes | Öğretim Yöntemleri: Anlatım |
| 10 | Fighting method in the presence of bacteriophage | lecture notes, project outputs and articles in our laboratory | Öğretim Yöntemleri: Anlatım, Gösteri, Deney / Laboratuvar |
| 11 | Fighting methods using various disinfectants, Effects of radiation on biofilm | lecture notes,benefit from developments in the hygiene sector | Öğretim Yöntemleri: Anlatım, Grup Çalışması |
| 12 | the mechanism of Quorum sensing (cell-cell communication) in microorganisms | lecture notes | Öğretim Yöntemleri: Anlatım |
| 13 | The role of Quorum sensing in biofilm formation | lecture notes | Öğretim Yöntemleri: Anlatım |
| 14 | The role of Quarum Quenching mechanism on biofilm formation | lecture notes and various articles | Öğretim Yöntemleri: Anlatım, Grup Çalışması, Bireysel Çalışma |
| 15 | the problems of biofilms in industry . Besides, learn about in industry how to use of exopolysaccharide which is in biofilm structure.Recent developments,. | lecture notes | Öğretim Yöntemleri: Anlatım, Tartışma |
| 16 | Term Exams | Ölçme Yöntemleri: Yazılı Sınav, Ödev |
|
| 17 | Term Exams | Ölçme Yöntemleri: Yazılı Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 2 | 28 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 6 | 84 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 2 | 6 | 12 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 6 | 6 |
| Final Exam | 1 | 12 | 12 |
| Total Workload (Hour) | 142 | ||
| Total Workload / 25 (h) | 5,68 | ||
| ECTS | 6 ECTS | ||