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Information
| Code | BFZ690 |
| Name | Isolated samples preparation-II |
| Term | 2024-2025 Academic Year |
| Semester | . Semester |
| Duration (T+A) | 2-2 (T-A) (17 Week) |
| ECTS | 4 ECTS |
| National Credit | 3 National Credit |
| Teaching Language | Türkçe |
| Level | Doktora Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Prof. Dr. IŞIL ÖCAL |
Course Goal / Objective
To produce disease and physiological models in experimental animals (such as diabetes, tumor, pregnancy process, diabetic neuropathy)
Course Content
Experimental animal models used in biophysical research, experimental animal models, comparison of experimental anatomy and physiology, experimental disease and physiological models are explained. Structure of muscles, dissection, preparation of preparations, biomechanical properties of muscles and recording, effects of pharmacological agents on muscles are taught. The student knows the experimental diabetes mellitus and tumor formation methods and development, the feeding and care of animals during the diabetic process, their cleanliness, control, creation and evaluation of experimental diabetic neuropathy.
Course Precondition
There is no prerequisite for the lesson
Resources
Surgical Research (Research Planning, Evaluation and Presentation, Experimental Animals, Specific Experimental Models Nobel Bookstore, Turkey 2005
Notes
Katzung BG. Basic and Clinical Pharmacology, Prentice Hall International Inc. Connecticut America1995
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Knows the animals used in experimental research and the anatomical and physiological structures of these animals. |
| LO02 | Knows ethical rules in experimental animals. |
| LO03 | Knows the differences between human physiology and anatomical structure. |
| LO04 | Knows the dissection of muscles from the experimental animal and preparation of preparations. |
| LO05 | Knows the anatomy of experimental animals |
| LO06 | Knows the anatomy and physiology of experimental animals |
| LO07 | Learns blood collection places, collection and features from experimental animals. |
| LO08 | Learns disease models in experimental animals |
| LO09 | Learns the agents in the development of diabetes in experimental animals. |
| LO10 | Learns the biomechanical and bioelectric effects of diabetes on muscles |
| LO11 | Learns diabetic neuropathy and knows the tests used in diabetic neuropathy |
| LO12 | Learns and applies analgesia and anesthesia in experimental animals. |
| LO13 | Learns and applies euthanasia in experimental animals |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | To learn the basic information about the field | 2 |
| PLO02 | Bilgi - Kuramsal, Olgusal | To be able to establish experimental work in laboratory | 5 |
| PLO03 | Bilgi - Kuramsal, Olgusal | To prepare a project proposal by itself | |
| PLO04 | Bilgi - Kuramsal, Olgusal | To plan an experimental research | 2 |
| PLO05 | Bilgi - Kuramsal, Olgusal | To make a report as a result of the research | |
| PLO06 | Bilgi - Kuramsal, Olgusal | To be able to interpret research findings | 2 |
| PLO07 | Bilgi - Kuramsal, Olgusal | Having analytical thinking mechanism related to the field Accessing reliable information Creating and writing a research project Study and research based on ethic values | 1 |
| PLO08 | Bilgi - Kuramsal, Olgusal | Ability to transfer the theoretical knowledge to the audience in a systematic way | 2 |
| PLO09 | Bilgi - Kuramsal, Olgusal | To have scientific thought systematic about the profession | 3 |
| PLO10 | Bilgi - Kuramsal, Olgusal | Kendi başına bir proje önerisi hazırlayabilmek | 2 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Using the animals in experimental researches and their properties | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Deney / Laboratuvar |
| 2 | Compare to anatomical and physiological properties of used the experimental animals according to human-beings | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Deney / Laboratuvar |
| 3 | Used the experimental animals, ethic rules, dissection and prepare the preparation, | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Deney / Laboratuvar |
| 4 | Examination of muscle and nerve structures in animals (striated, smooth and cardiac muscles, sciatic nerve etc.) and their dissections | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Alıştırma ve Uygulama |
| 5 | Biomechanical and bioelectrical properties of muscles and recording (contraction-relaxation) | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Alıştırma ve Uygulama |
| 6 | The properties of smooth muscle and their recording | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Alıştırma ve Uygulama |
| 7 | Effects of pharmacological and anesthesia agents on muscles | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Soru-Cevap, Alıştırma ve Uygulama |
| 8 | Mid-Term Exam | Mid-Term Exam | Ölçme Yöntemleri: Yazılı Sınav, Ödev, Performans Değerlendirmesi |
| 9 | Set up some diseases and physiological models in experimental animals (diabetes mellitus, cancer and pregnancy) | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Alıştırma ve Uygulama |
| 10 | Using the anesthesia and pharmacologic agents in diabetic animals | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Alıştırma ve Uygulama |
| 11 | Animal care, nutrition, cleaning and health control and taking blood | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Alıştırma ve Uygulama |
| 12 | Compare to diabetes mellitus in human-beings and experimental animal and their controlling | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Alıştırma ve Uygulama, Anlatım |
| 13 | Introduction of diseases in chronic diabetic animals and diabetic neuropathy | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Alıştırma ve Uygulama |
| 14 | Disadvantages of diabetic neuropathy and determine of diabetic neuropathy | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Alıştırma ve Uygulama |
| 15 | Measurement of mechanical and thermal reflex in diabetic neuropathy | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Alıştırma ve Uygulama |
| 16 | Final Exams | Final Exams | Ölçme Yöntemleri: Yazılı Sınav, Ödev, Performans Değerlendirmesi |
| 17 | Final Exams | Final Exams | Ölçme Yöntemleri: Yazılı Sınav, Ödev, Performans Değerlendirmesi |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 4 | 56 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 2 | 28 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 1 | 4 | 4 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 8 | 8 |
| Final Exam | 1 | 12 | 12 |
| Total Workload (Hour) | 108 | ||
| Total Workload / 25 (h) | 4,32 | ||
| ECTS | 4 ECTS | ||