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Information
| Code | BFZ641 |
| Name | Ionic channels and HH-model |
| Term | 2024-2025 Academic Year |
| Semester | . Semester |
| Duration (T+A) | 2-2 (T-A) (17 Week) |
| ECTS | 5 ECTS |
| National Credit | 3 National Credit |
| Teaching Language | Türkçe |
| Level | Doktora Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Prof.Dr. İSMAİL GÜNAY |
Course Goal / Objective
To teach the ion channels and their properties in the muscle and nerve tissues stimulated in the living system and to teach the application of the laws of physics over the electrical equivalent circuit.
Course Content
Ion channels, Na channels, K channels, Cl channels, Ca channels, Uniport symport etc gates, channels in nerves, ion channels in muscles, physical factors affecting channels, chemical properties affecting channels, channel blockers, electrical circuits of channels, accepted electrical HH model
Course Precondition
The lesson has no prerequisites
Resources
Lecture notes (For Medical Faculty Students - İsmail Günay) Biophysics (Ferit Pehlivan) Biophysics (Gürbüz Çelebi) Internet Search
Notes
Internet Search
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Learns the channels in the cell membrane |
| LO02 | Knows Na channels in the cell membrane in detail |
| LO03 | Knows the Ca channels in the cell membrane in detail. |
| LO04 | Knows ion channels in muscles |
| LO05 | Knows ion channels in nerves |
| LO06 | Learns the HH model of the electrical equivalent circuit of channels |
| LO07 | Compares ion channels according to their locations |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | To learn the basic information about the field | 3 |
| PLO02 | Bilgi - Kuramsal, Olgusal | To be able to establish experimental work in laboratory | 3 |
| PLO03 | Bilgi - Kuramsal, Olgusal | To prepare a project proposal by itself | |
| PLO04 | Bilgi - Kuramsal, Olgusal | To plan an experimental research | 2 |
| PLO05 | Bilgi - Kuramsal, Olgusal | To make a report as a result of the research | 1 |
| PLO06 | Bilgi - Kuramsal, Olgusal | To be able to interpret research findings | 2 |
| PLO07 | Bilgi - Kuramsal, Olgusal | Having analytical thinking mechanism related to the field Accessing reliable information Creating and writing a research project Study and research based on ethic values | 3 |
| PLO08 | Bilgi - Kuramsal, Olgusal | Ability to transfer the theoretical knowledge to the audience in a systematic way | 2 |
| PLO09 | Bilgi - Kuramsal, Olgusal | To have scientific thought systematic about the profession | 4 |
| PLO10 | Bilgi - Kuramsal, Olgusal | Kendi başına bir proje önerisi hazırlayabilmek |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | What are ion channels? | Student reads the related section before class | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 2 | Na channels | Student reads the related section before class | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 3 | K channels | Student reads the related section before class | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 4 | Cl channels | Student reads the related section before class | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 5 | Ca channels | Student reads the related section before class | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 6 | Ion channels in nerves | Student reads the related section before class | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 7 | Ion channels in nerves and their properties | Student reads the related section before class | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 8 | Mid-Term Exam | The student works on the topics discussed. | Ölçme Yöntemleri: Yazılı Sınav, Ödev, Performans Değerlendirmesi |
| 9 | Ion channels in the muscles and their properties | Student reads the related section before class | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 10 | Function of ion channels | Student reads the related section before class | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 11 | Physical and chemical properties affecting ion channels | Student reads the related section before class | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 12 | Electrical equivalent circuit of ion channels | Student reads the related section before class | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 13 | HH model of electrical equivalent circuit of channels | Student reads the related section before class | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 14 | Application of the laws of physics in the HH model | Student reads the related section before class | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 15 | Comparison of ion channels and blockers | Student reads the related section before class | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 16 | Term Exams | Ölçme Yöntemleri: Yazılı Sınav, Ödev, Performans Değerlendirmesi |
|
| 17 | Term Exams | Ölçme Yöntemleri: Yazılı Sınav, Ödev, Performans Değerlendirmesi |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 4 | 56 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 3 | 42 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 1 | 3 | 3 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 8 | 8 |
| Final Exam | 1 | 16 | 16 |
| Total Workload (Hour) | 125 | ||
| Total Workload / 25 (h) | 5,00 | ||
| ECTS | 5 ECTS | ||