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Information
| Code | BFZ503 |
| Name | Using the Experimental Animal models in Biophysics Researches |
| Term | 2024-2025 Academic Year |
| Semester | . Semester |
| Duration (T+A) | 2-2 (T-A) (17 Week) |
| ECTS | 4 ECTS |
| National Credit | 3 National Credit |
| Teaching Language | Türkçe |
| Level | Yüksek Lisans Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Prof. Dr. IŞIL ÖCAL |
Course Goal / Objective
To produce disease and physiological models in experimental animals (such as diabetes, tumor, pregnancy process, diabetic neuropathy)
Course Content
Experimental animal models used in biophysical research, experimental animal models, comparison of experimental anatomy and physiology, experimental disease and physiological models are explained. Structure of muscles, dissection, preparation of preparations, biomechanical properties of muscles and recording, effects of pharmacological agents on muscles are taught. The student knows the experimental diabetes mellitus and tumor formation methods and development, the feeding and care of animals during the diabetic process, their cleanliness, control, creation and evaluation of experimental diabetic neuropathy.
Course Precondition
The lesson has no prerequisites
Resources
Surgical Research (Research Planning, Evaluation and Presentation, Experimental Animals, Specific Experimental Models Nobel Bookstore, Turkey 2005
Notes
Internet Research
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Knows the animals used in experimental research and the anatomical and physiological structures of these animals. |
| LO02 | Knows ethical rules in experimental animals. |
| LO03 | Knows the differences between human physiology and anatomical structure. |
| LO04 | Knows the dissection of muscles from the experimental animal and preparation of preparations. |
| LO05 | Knows muscle types and biomechanical and bioelectric properties and recording of these muscles. |
| LO06 | Knows the anesthetic and pharmacological agents used in experimental animals. |
| LO07 | Diabetes in experimental animals, tumor formation methods, physiological process knows the formation of pregnancy. |
| LO08 | Knows the formation of experimental diabetic animals. |
| LO09 | Know the severity of experimental diabetes and take blood. |
| LO10 | Knows the neuropathy in experimental diabetic animals, |
| LO11 | Knows the evaluation of diabetic neuropathy. |
| LO12 | Knows the differences between human and animal diabetic neuropathy. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Learns basic information about the field | 4 |
| PLO02 | Bilgi - Kuramsal, Olgusal | Sets up and works experimental setups in the laboratory | 3 |
| PLO03 | Bilgi - Kuramsal, Olgusal | Prepares a project proposal on its own | 4 |
| PLO04 | Bilgi - Kuramsal, Olgusal | Plans an experimental study | 2 |
| PLO05 | Bilgi - Kuramsal, Olgusal | Reports the research result | 3 |
| PLO06 | Bilgi - Kuramsal, Olgusal | Interpret the research findings | |
| PLO07 | Beceriler - Bilişsel, Uygulamalı | Has the analytical thinking mechanism related to the field, Reaches reliable information. Creates and writes a research project, works and researches based on ethical values. | |
| PLO08 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | She/he systematically transfers the theoretical knowledge she has researched to the audience. | |
| PLO09 | Yetkinlikler - Öğrenme Yetkinliği | Have a scientific thinking systematic in relation to their profession. |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Using the animals in experimental researches and their properties | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Gösteri, Deney / Laboratuvar |
| 2 | Compare to anatomical and physiological properties of used the experimental animals according to human-beings | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Gösteri, Deney / Laboratuvar |
| 3 | Using the experimental animals, ethic rules, dissection and prepare the preparation, | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Gösteri, Deney / Laboratuvar |
| 4 | Examination of muscle and nerve structures in animals (striated, smooth and cardiac muscles, sciatic nerve etc.) and their dissections | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Gösteri, Deney / Laboratuvar |
| 5 | Biomechanical and bioelectrical properties of muscles and recording (contraction-relaxation) | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Gösteri, Deney / Laboratuvar |
| 6 | Smooth muscle and their recording | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Gösteri, Deney / Laboratuvar |
| 7 | Pharmacological and anesthesia agents on muscles | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Gösteri, Deney / Laboratuvar |
| 8 | Mid-Term Exam | Studying the lessons taught throughout the semester | Ölçme Yöntemleri: Yazılı Sınav, Ödev, Performans Değerlendirmesi |
| 9 | Set up some diseases and physiological models in experimental animals (diabetes mellitus, cancer and pregnancy) | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Gösteri, Deney / Laboratuvar |
| 10 | Using the anesthesia and pharmacologic agents in diabetic animals | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Gösteri, Deney / Laboratuvar |
| 11 | Animal care, nutrition, cleaning and health control and taking blood | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Gösteri, Deney / Laboratuvar |
| 12 | Compare to diabetes mellitus in human-beings and experimental animal and their controlling | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Gösteri, Deney / Laboratuvar |
| 13 | Diseases in chronic diabetic animals and diabetic neuropathy | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Gösteri, Deney / Laboratuvar |
| 14 | Disadvantages of diabetic neuropathy and determine of diabetic neuropathy | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Gösteri, Deney / Laboratuvar |
| 15 | Measurement of mechanical and thermal reflex in diabetic neuropathy | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Deney / Laboratuvar |
| 16 | Term Exams | homework presentations | Ölçme Yöntemleri: Yazılı Sınav, Ödev, Performans Değerlendirmesi |
| 17 | Term Exams | Studying the lessons taught throughout the semester | Ölçme Yöntemleri: Yazılı Sınav, Ödev, Performans Değerlendirmesi |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 4 | 56 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 2 | 28 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 8 | 8 |
| Final Exam | 1 | 16 | 16 |
| Total Workload (Hour) | 108 | ||
| Total Workload / 25 (h) | 4,32 | ||
| ECTS | 4 ECTS | ||