TÜRKÇE
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Information
| Code | EFR509 |
| Name | |
| Term | 2024-2025 Academic Year |
| Semester | . Semester |
| Duration (T+A) | 2-0 (T-A) (17 Week) |
| ECTS | 5 ECTS |
| National Credit | 2 National Credit |
| Teaching Language | Türkçe |
| Level | Yüksek Lisans Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator |
Course Goal / Objective
Defines and comprehends the basic information about neuromediators in the central nervous system, impulse transmission, events that play a role in the modulation of impulse transmission. Classifies drugs that affect the central nervous system. Explains and compares the mechanism of action, side effects, contraindications and interactions of drugs used in the central nervous system.
Course Content
Neurotransmitters in the central nervous system, conduction pathways and drugs used in central nervous system diseases, mechanisms of action, side effects and interactions of drugs
Course Precondition
None
Resources
Lippincott's Illustrated Reviews: Pharmacology, Lippincott Williams & Wilkins,2018 Goodman and Gilman's The Pharmacologi-cal Basis of Therapeutics-13 th Edition, McGraw-Hill Medical Books, 2018
Notes
https://go.drugbank.com/
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | The central nervous system classifies neurotransmitters. |
| LO02 | Comprehends the neurochemical mechanism of impulse transmission in the central nervous system. |
| LO03 | Explain the pathways affecting the modulation of impulse transmission in the central nervous system. |
| LO04 | Classify drugs that affect the central nervous system. |
| LO05 | Explain the mechanism of action of drugs affecting the central nervous system. |
| LO06 | Explain the side, contraindications and uses of drugs that affect the central nervous system. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Explain the mechanisms of action of drugs, their pharmacokinetic and pharmacodynamic effects. | 4 |
| PLO02 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Acts in accordance with ethical and legal principles in the field of pharmacology. | 1 |
| PLO03 | Beceriler - Bilişsel, Uygulamalı | Can project and conduct research in the field of pharmacology and analyze and interpret data. | |
| PLO04 | Yetkinlikler - Alana Özgü Yetkinlik | It plays an active role in rational drug use and provides counseling to the patient for the correct use of the drug. | 4 |
| PLO05 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Can convey the current developments or studies in the field of pharmacology verbally or in writing. | 3 |
| PLO06 | Bilgi - Kuramsal, Olgusal | Follows scientific literature and current developments in the field of pharmacology. | 3 |
| PLO07 | Bilgi - Kuramsal, Olgusal | Establishes a relationship between the effects, mechanisms of action and drug interactions of drugs. | 5 |
| PLO08 | Bilgi - Kuramsal, Olgusal | Explain the physiopathology of various diseases and evalue the drugs used in the treatment of these diseases. | 5 |
| PLO09 | Beceriler - Bilişsel, Uygulamalı | Knows and uses good laboratory practices. | |
| PLO10 | Beceriler - Bilişsel, Uygulamalı | Uses the theoretical and applied knowledge gained in the field of pharmacology. | 3 |
| PLO11 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Have the ability to take part in in vitro/in vivo animal studies. |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Communication tools and receptors between neurons, Synapses and the effects of drugs | The subject should be reviewed from the textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Beyin Fırtınası |
| 2 | Synthesis, Receptors, and Roles of Dopamine, Serotonin, Adrenalin and Noradrenalin in the Central Nervous System in Physiological and Pathological Events | The subject should be reviewed from the textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Beyin Fırtınası |
| 3 | Synthesis, Receptors, and Roles of Acetylcholine, GABA, Glisin, Glutamat in the Central Nervous System in Physiological and Pathological Events | The subject should be reviewed from the textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Beyin Fırtınası |
| 4 | Classification, Drugs Used in Alzheimer, Mechanisms of Action, Pharmacological Properties, Side Effects, Contraindicated Conditions and Therapeutic Uses | The subject should be | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Beyin Fırtınası |
| 5 | Drugs Used in Mood Disorder, Mechanisms of Action, Pharmacological Properties, Side Effects, Contraindicated Conditions and Therapeutic Uses | The subject should be | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Beyin Fırtınası |
| 6 | Drugs Used in Parkinson's Disease and Other Movement Disorders and Alzheimer's Treatment, Mechanisms of Action, Pharmacological Properties, Side Effects, Contraindications and Therapeutic Uses | The subject should be reviewed from the textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Beyin Fırtınası |
| 7 | Antiepileptic Drugs, Mechanisms of Action, Pharmacological Properties, Side Effects, Contraindications and Therapeutic Uses | The subject should be reviewed from the textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Beyin Fırtınası |
| 8 | Mid-Term Exam | Prepare a presentation from literatures | Ölçme Yöntemleri: Ödev |
| 9 | Central Nervous System Stimulants and Weight Loss Drugs, Mechanisms of Action, Pharmacological Properties, Side Effects, Contraindications and Therapeutic Uses | The subject should be reviewed from the textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Beyin Fırtınası |
| 10 | Non-Sterodial Anti-Inflammatory Drugs, Mechanisms of Action, Pharmacological Properties, Side Effects, Contraindications and Therapeutic Uses | The subject should be reviewed from the textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Beyin Fırtınası |
| 11 | Mechanisms of Action, Pharmacological Properties, Side Effects, Contraindications and Therapeutic Uses of Opioid Analgesics | The subject should be reviewed from the textbooks | Öğretim Yöntemleri: Anlatım, Beyin Fırtınası |
| 12 | Drug Addiction and Abuse | The subject should be reviewed from the textbooks | Öğretim Yöntemleri: Anlatım, Beyin Fırtınası |
| 13 | General Anesthetic Drugs, Mechanisms of Action of General Anesthetics, Pharmacological Properties, Side Effects, Contraindications and Therapeutic Uses | The subject should be reviewed from the textbooks | Öğretim Yöntemleri: Anlatım, Beyin Fırtınası |
| 14 | Local Anesthetics, Mechanisms of Action, Pharmacological Properties, Side Effects, Contraindications and Therapeutic Uses of Local Anesthetics | The subject should be reviewed from the textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 15 | Mechanisms of Action, Pharmacological Properties, Side Effects, Contraindications and Therapeutic Uses of Neuromuscular Blocking Drugs and Centrally Acting Muscle Relaxant | The subject should be reviewed from the textbooks | Öğretim Yöntemleri: Anlatım, Tartışma, Beyin Fırtınası |
| 16 | Overview | Should study to presentations | Öğretim Yöntemleri: Tartışma |
| 17 | Term Exams | Should study to presentations | Ölçme Yöntemleri: Yazılı Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 2 | 28 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 4 | 56 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 1 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 10 | 10 |
| Final Exam | 1 | 24 | 24 |
| Total Workload (Hour) | 118 | ||
| Total Workload / 25 (h) | 4,72 | ||
| ECTS | 5 ECTS | ||