BİO646 Advanced Medical Genetics

5 ECTS - 3-0 Duration (T+A)- . Semester- 3 National Credit

Information

Code BİO646
Name Advanced Medical Genetics
Term 2024-2025 Academic Year
Semester . Semester
Duration (T+A) 3-0 (T-A) (17 Week)
ECTS 5 ECTS
National Credit 3 National Credit
Teaching Language Türkçe
Level Doktora Dersi
Type Normal
Mode of study Yüz Yüze Öğretim
Catalog Information Coordinator Prof. Dr. HÜSNÜ ÜMİT LÜLEYAP


Course Goal / Objective

The aim of this course is to provide the students to have knowledge about human genome project, genetics of aging, hearing, genomics of neuromuscular diseases, apoptosis, genetics of cancer, genetic screening and to provide the students to make studies on these issues.

Course Content

Genome project, Genetic Screening, Developmental Genetics, Genetic Control of Gender, Hearing Genetics, Evolutionary genetics, transgenetics, Genetics of neuromuscular disease, immunogenetics, Genetics of aging, Cancer genetics, Genetics of metabolic diseases, Nutrigenetik, Apoptosis

Course Precondition

BİO 502 Fundamentals of medical genetics

Resources

1) M. Connor & M. Ferguson-SmithEssential Medical Genetics. Fifth Edition. Blckwell Science.

Notes

1) M. Connor & M. Ferguson-SmithEssential Medical Genetics. Fifth Edition. Blckwell Science.


Course Learning Outcomes

Order Course Learning Outcomes
LO01 Have knowledge about genome projects
LO02 Have knowledge about genetic screening tests
LO03 Have knowledge about developmental genetics
LO04 Have knowledge about hearing genetics
LO05 Knows the genetics of major neuromuscular diseases
LO06 Knows immunogenetics
LO07 Have knowledge about the genetics of aging
LO08 Knows cancer genetics
LO09 Have knowledge about metabolic diseases
LO10 Knows apoptosis (programmed cell death)


Relation with Program Learning Outcome

Order Type Program Learning Outcomes Level
PLO01 Bilgi - Kuramsal, Olgusal To make and interpret Medical Genetics, Molecular Genetics and Cytogenetic analyzes 4
PLO02 Bilgi - Kuramsal, Olgusal To have information about genetic diseases 4
PLO03 Bilgi - Kuramsal, Olgusal To have knowledge of Molecular Cell Biology 3
PLO04 Bilgi - Kuramsal, Olgusal To apply fluorescence in-situ hybridization (FISH) technique
PLO05 Bilgi - Kuramsal, Olgusal To make DNA isolation and PCR of all kinds of tissue 3
PLO06 Bilgi - Kuramsal, Olgusal To make cell culture of all kinds of tissue (blood, amniotic fluid, chorionic villus biopsy) 3
PLO07 Bilgi - Kuramsal, Olgusal To do cytogenetic analysis by recognizing human chromosomes separately 5
PLO08 Bilgi - Kuramsal, Olgusal To make QF-PCR and to interpret the results 3
PLO09 Bilgi - Kuramsal, Olgusal To have the knowledge and skills to teach Medical Biology and Genetics Courses in Medical Faculties 5
PLO10 Bilgi - Kuramsal, Olgusal To write and implement a research project on his/her own 3
PLO11 Bilgi - Kuramsal, Olgusal To write an article by collecting the information obtained at the end of the research 3
PLO12 Yetkinlikler - Öğrenme Yetkinliği To organize laboratory courses of Medical Biology and Genetics courses at undergraduate level 2


Week Plan

Week Topic Preparation Methods
1 Genome project Slide preparation Öğretim Yöntemleri:
Alıştırma ve Uygulama, Soru-Cevap
2 Genetic Screening Slide preparation Öğretim Yöntemleri:
Tartışma, Alıştırma ve Uygulama
3 Developmental Genetics Slide preparation Öğretim Yöntemleri:
Anlatım, Beyin Fırtınası
4 Genetic Control of Gender Slide preparation Öğretim Yöntemleri:
Anlatım
5 Hearing Genetics Slide preparation Öğretim Yöntemleri:
Anlatım
6 Evolutionary genetics Slide preparation Öğretim Yöntemleri:
Anlatım, Tartışma
7 Transgenetics Slide preparation Öğretim Yöntemleri:
Anlatım, Bireysel Çalışma
8 Mid-Term Exam Preparation of multiple-choice questions Öğretim Yöntemleri:
Soru-Cevap, Tartışma, Beyin Fırtınası
9 Genetics of neuromuscular diseases Slide preparation Öğretim Yöntemleri:
Anlatım
10 Immunogenetics Slide preparation Öğretim Yöntemleri:
Anlatım
11 Genetics of aging Slide preparation Öğretim Yöntemleri:
Anlatım
12 Cancer genetics Slide preparation Öğretim Yöntemleri:
Anlatım, Soru-Cevap
13 Genetics of metabolic diseases Slide preparation Öğretim Yöntemleri:
Anlatım
14 Nutrigenetik Slide preparation Öğretim Yöntemleri:
Anlatım
15 Apoptosis Slide preparation Öğretim Yöntemleri:
Soru-Cevap, Anlatım
16 Term Exams Preparation of multiple-choice questions Ölçme Yöntemleri:
Sözlü Sınav
17 Term Exams Preparation of multiple-choice questions Ölçme Yöntemleri:
Yazılı Sınav, Sözlü Sınav


Student Workload - ECTS

Works Number Time (Hour) Workload (Hour)
Course Related Works
Class Time (Exam weeks are excluded) 14 3 42
Out of Class Study (Preliminary Work, Practice) 14 3 42
Assesment Related Works
Homeworks, Projects, Others 4 8 32
Mid-term Exams (Written, Oral, etc.) 1 2 2
Final Exam 1 2 2
Total Workload (Hour) 120
Total Workload / 25 (h) 4,80
ECTS 5 ECTS

Update Time: 26.09.2024 11:59