VTS144 Methods of Discovery New Drugs

4 ECTS - 2-0 Duration (T+A)- 2. Semester- 2 National Credit

Information

Code VTS144
Name Methods of Discovery New Drugs
Term 2024-2025 Academic Year
Semester 2. Semester
Duration (T+A) 2-0 (T-A) (17 Week)
ECTS 4 ECTS
National Credit 2 National Credit
Teaching Language Türkçe
Level Lisans Dersi
Type Normal
Mode of study Yüz Yüze Öğretim
Catalog Information Coordinator Dr. Öğr. Üyesi ZEYNEP ÖZDEMİR KÜTAHYA
Course Instructor
1


Course Goal / Objective

Teaching new drug development and drug active ingredient synthesis strategies

Course Content

Accurate synthesis of drugs from various raw materials, pharmaceutical active raw material synthesis and synthesis method development

Course Precondition

The course has no prerequisites.

Resources

S. Oğuz Kayaalp. Principles of Clinical Pharmacology and Basic Regulations. Pelikan Yayıncılık Ltd. Şti., 2013, 5.Edition. ISBN: 978-605-5270-36-0

Notes

Dikensoy Öner. Why Experimental Studies? Turk Toraks Dergisi, 2013, 14 (2): 3-5.


Course Learning Outcomes

Order Course Learning Outcomes
LO01 Defines the original drug.
LO02 Defines the equivalent (generic) drug.
LO03 Summarizes drug/vaccine clinical development phases.
LO04 Summarizes ways of finding new drugs.
LO05 Defines drug development based on combinatorial chemistry and high-throughput screening methods.
LO06 Explains drug molecule design and virtual scanning with the help of computer.
LO07 Defines the contribution of developments in biotechnology, genomics and pharmacogenomics to drug development.
LO08 Explains the importance of economic incentives and the expenditure/earnings profile in new drug development.


Relation with Program Learning Outcome

Order Type Program Learning Outcomes Level
PLO01 Bilgi - Kuramsal, Olgusal Recognize animal species and breeds in terms of their morphological, functional (physiological, biochemical) and behavioral characteristics.
PLO02 Beceriler - Bilişsel, Uygulamalı Determines the correct approach area for the patients by evaluating the examination, operation etc. practices in the clinic according to the topographic anatomy.
PLO03 Yetkinlikler - Alana Özgü Yetkinlik Produces solutions to field-specific problems in line with scientific data/evidence. 3
PLO04 Yetkinlikler - İletişim ve Sosyal Yetkinlik Based on his/her professional skills and authority, he/she implements social projects and plans with social awareness. 3
PLO05 Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği Becomes conscious of performing his profession by being aware of his powers and responsibilities. 4
PLO06 Bilgi - Kuramsal, Olgusal Learn the structures of living organisms, their components at the cellular level, and chemical processes in the body.
PLO07 Beceriler - Bilişsel, Uygulamalı Learn to use biochemical processes in diagnostic processes by evaluating the information obtained with cause-effect relationships.
PLO08 Yetkinlikler - Alana Özgü Yetkinlik Demonstrates the ability to possess and defend the ethical values of the veterinary profession.
PLO09 Yetkinlikler - Öğrenme Yetkinliği Understands the methods of producing and using scientific knowledge in his/her professional field. 2
PLO10 Bilgi - Kuramsal, Olgusal Knows the sources of drugs, their physical and chemical properties and preparation. 5
PLO11 Bilgi - Kuramsal, Olgusal Knows the effects and side effects of medications on patients.
PLO12 Beceriler - Bilişsel, Uygulamalı Prescribes and administers medications in accordance with legislation.
PLO13 Beceriler - Bilişsel, Uygulamalı Applies the principles of diagnosis and general treatment of poisoning in animals.
PLO14 Bilgi - Kuramsal, Olgusal Learns general diagnosis and treatment protocols of animal diseases. 2
PLO15 Beceriler - Bilişsel, Uygulamalı Applies necessary measures, including biosecurity, to control infectious diseases.
PLO16 Yetkinlikler - Alana Özgü Yetkinlik Clinically recognizes zoonotic and notifiable diseases and knows how to take appropriate precautions.
PLO17 Beceriler - Bilişsel, Uygulamalı Performs systematic necropsy on dead animals, evaluates the findings, knows the methods of preserving tissues and directs them to the necessary laboratories.
PLO18 Bilgi - Kuramsal, Olgusal Knows the formation mechanisms of animal diseases and the pathological effects they cause in the body.
PLO19 Yetkinlikler - Alana Özgü Yetkinlik Determines the methods of diagnosis, prevention, treatment and operation of surgical diseases in different animal species.
PLO20 Beceriler - Bilişsel, Uygulamalı Uses the main treatment methods of surgical diseases in animal species. Evaluates and monitors patients in the postoperative period.
PLO21 Beceriler - Bilişsel, Uygulamalı Knows and applies sedation and anesthesia methods safely according to animal species.
PLO22 Beceriler - Bilişsel, Uygulamalı Knows and applies pain management methods.
PLO23 Beceriler - Bilişsel, Uygulamalı Correctly applies biosafety principles such as sterilization of clinical and laboratory equipment and clothing.
PLO24 Bilgi - Kuramsal, Olgusal Applies the information about selection, hybridization and artificial insemination to be able to evaluate the productivity of animal breeds and to be able to carry out breeding work when necessary.
PLO25 Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği Examines scientific techniques and methods according to facts related to veterinary services and takes analysis or methodological responsibility for problems.
PLO26 Yetkinlikler - Alana Özgü Yetkinlik Determines clinical diagnosis and treatment protocols for diseases in different animal species.
PLO27 Yetkinlikler - Öğrenme Yetkinliği Learns sufficient technological knowledge in the hygienic production, manufacturing, presentation for consumption and sales of animal foods produced for human consumption and/or foods containing animal products in their composition.
PLO28 Yetkinlikler - Alana Özgü Yetkinlik Performs health checks on animal foodstuffs offered for consumption.
PLO29 Yetkinlikler - İletişim ve Sosyal Yetkinlik Gains awareness about environmental and veterinary public health issues. 3
PLO30 Yetkinlikler - Öğrenme Yetkinliği Follows updated legislation regarding veterinary services and uses it when necessary. 3
PLO31 Yetkinlikler - Öğrenme Yetkinliği Knows the contribution of imaging methods in diagnosis. Performs an examination appropriate for the case by applying radiation safety according to current regulations.
PLO32 Yetkinlikler - Alana Özgü Yetkinlik Treats all animals in emergency cases and applies first aid methods.
PLO33 Beceriler - Bilişsel, Uygulamalı Prepares care and feeding protocols specific to animal species.
PLO34 Yetkinlikler - İletişim ve Sosyal Yetkinlik Provides information to animal owners about breeding principles by evaluating the physical condition, welfare and rearing conditions of domestic animals.
PLO35 Yetkinlikler - Öğrenme Yetkinliği Learns lifelong learning and training methods to maintain professional development and skills. 3
PLO36 Yetkinlikler - İletişim ve Sosyal Yetkinlik Gains awareness of working in cooperation with other colleagues within the framework of professional ethics and deontology rules.
PLO37 Yetkinlikler - İletişim ve Sosyal Yetkinlik Gains the ability to communicate effectively with patients, the community, colleagues and relevant authorities using appropriate language.
PLO38 Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği Independently understand and interpret articles and presentations published in veterinary medicine and other related scientific fields. 2
PLO39 Yetkinlikler - Alana Özgü Yetkinlik When necessary, euthanizes animals using appropriate methods and respecting the feelings of animal owners.
PLO40 Bilgi - Kuramsal, Olgusal Learns how to properly dispose of dead animal material, tissue samples, medical and chemical waste.
PLO41 Beceriler - Bilişsel, Uygulamalı Evaluates laboratory results of animal diseases and applies correct diagnosis, prognosis and treatment methods based on the data obtained.
PLO42 Yetkinlikler - Öğrenme Yetkinliği Knows to keep clinical and patient records with proper and scientific methods.
PLO43 Yetkinlikler - Öğrenme Yetkinliği Learns to prepare case and necropsy reports in a way that is understandable to the society and relevant institutions at a professional level when necessary.
PLO44 Yetkinlikler - Öğrenme Yetkinliği Knows how to manage animal production businesses and make appropriate management plans, while taking into account basic medical principles.
PLO45 Yetkinlikler - Alana Özgü Yetkinlik Understands the economic, sociocultural and emotional conditions in which veterinarians operate and positions themselves accordingly.


Week Plan

Week Topic Preparation Methods
1 Original drug, equivalent drug definition Lecture notes Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
2 Drug/vaccine clinical development phases Lecture notes Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
3 Finding medicine using folk remedies and natural resources Lecture notes Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
4 Drug development by modifying or imitating drugs of natural origin Lecture notes Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
5 Finding new target molecules with functional importance in the body and designing chemical substances that activate or inhibit them Lecture notes Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
6 Drug development by mimicking endogenous active substances such as neuromediators, hormones, autocoids and cytokines Lecture notes Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
7 Finding a drug by imitating another company's drug Lecture notes Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
8 Mid-Term Exam Ölçme Yöntemleri:
Yazılı Sınav, Sözlü Sınav, Ödev
9 Developing new drugs by examining the side effects of existing drugs Lecture notes Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
10 Finding a drug by a relatively random approach or by chance Lecture notes Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
11 Drug development based on combinatorial chemistry and high-throughput screening methods Lecture notes Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
12 Computer-assisted drug molecule design and virtual scanning Lecture notes Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
13 The impact of biotechnology on drug development and production Lecture notes Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
14 Contribution of developments in genomics and pharmacogenomics to drug development Lecture notes Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
15 Importance of economic incentives and expenditure/earnings profile in new drug development Lecture notes Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
16 Term Exams Ölçme Yöntemleri:
Yazılı Sınav, Sözlü Sınav, Ödev
17 Term Exams Ölçme Yöntemleri:
Yazılı Sınav, Sözlü Sınav, Ödev


Student Workload - ECTS

Works Number Time (Hour) Workload (Hour)
Course Related Works
Class Time (Exam weeks are excluded) 14 2 28
Out of Class Study (Preliminary Work, Practice) 14 4 56
Assesment Related Works
Homeworks, Projects, Others 0 0 0
Mid-term Exams (Written, Oral, etc.) 1 2 2
Final Exam 1 4 4
Total Workload (Hour) 90
Total Workload / 25 (h) 3,60
ECTS 4 ECTS

Update Time: 15.10.2024 11:51