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Information
| Code | BİO511 |
| Name | Bacterial Genetics |
| Term | 2024-2025 Academic Year |
| Semester | . Semester |
| Duration (T+A) | 2-2 (T-A) (17 Week) |
| ECTS | 5 ECTS |
| National Credit | 3 National Credit |
| Teaching Language | Türkçe |
| Level | Yüksek Lisans Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Prof. Dr. DAVUT ALPTEKİN |
Course Goal / Objective
To have a general knowledge about bacteria, to know the differences between pathogen and non-pathogenic bacteria, to know the surface properties of bacteria in bacteria and to have information about bacterial genome and to learn gene transfer between bacteria.
Course Content
General information about bacteria. Bacteria reproduction. Cellular structures of bacteria. Intracellular structures. External structures of bacteria; surface extensions (delete, flagel, pilus). Bacterial genome; DNA, RNA. Regulation of gene functions in bacteria, operon theory. Mutations in bacteria. Bacteriophages, morphological structures, classification. Life cycles of phages. Transformation of genetic material between bacteria, Transformation. Genetic transfer of bacteria, Conjugation. Transfer of genetic material between bacteria, transduction. Plasmids.
Course Precondition
None
Resources
Muvakfak AKMAN, Bakteria Genetics.
Notes
Lecturer Lecture Notes and Slides
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Learns general information about bacteria. |
| LO02 | Learns the reproduction of bacteria. |
| LO03 | The cellular structure of the bacteria, will have information about the structures and organelles inside the cell. |
| LO04 | Bakterilerin dış yapılarını ve yüzey uzantılarını öğrenir. (sil, flagel, pilus) |
| LO05 | Have information about bacterial genome (DNA, RNA). |
| LO06 | Learns the regulation of gene functions in bacteria and the theory of operon. |
| LO07 | Learns mutations and their effects in bacteria. |
| LO08 | Learns bacteriophages, morphological structures and classification. |
| LO09 | Learn the life cycles of phages (lysogenic and lytic cycles). |
| LO10 | Learns the transmission of genetic material among bacteria. (Transformation, Transduction, Conjugation). |
| LO11 | Gains knowledge about plasmids. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | To comprehend the structure and functions of cells and organelles which constitute the basic structure of life | 4 |
| PLO02 | Bilgi - Kuramsal, Olgusal | To recognize the functions of tissue and organ systems | |
| PLO03 | Bilgi - Kuramsal, Olgusal | To examine the structure of genetic material | 4 |
| PLO04 | Bilgi - Kuramsal, Olgusal | To recognize genetic diseases and genes that cause these diseases | |
| PLO05 | Bilgi - Kuramsal, Olgusal | To learn the structure of genes | 1 |
| PLO06 | Bilgi - Kuramsal, Olgusal | To define chromosome and gene mutations | 1 |
| PLO07 | Bilgi - Kuramsal, Olgusal | To classify heredity forms (autosomal dominant, autosomal recessive, gender-dependent dominant and recessive inheritance models) | |
| PLO08 | Bilgi - Kuramsal, Olgusal | To use molecular and cytogenetic analysis | |
| PLO09 | Bilgi - Kuramsal, Olgusal | To be able to explain the numerical and structural anomalies of autosomal and sex chromosomes | |
| PLO10 | Bilgi - Kuramsal, Olgusal | To make DNA isolation from all kinds of tissues | |
| PLO11 | Bilgi - Kuramsal, Olgusal | To prepare PCR | |
| PLO12 | Bilgi - Kuramsal, Olgusal | To make and interpret agarose and polyacrylamide gel electrophoresis | |
| PLO13 | Bilgi - Kuramsal, Olgusal | To measure the obtained DNA on the spectrophotometer | |
| PLO14 | Bilgi - Kuramsal, Olgusal | To apply and interpret QF-PCR technique | |
| PLO15 | Bilgi - Kuramsal, Olgusal | To make cell culture from blood, amnion, chorionic villus biopsy specimens and to obtain chromosome preparation | |
| PLO16 | Bilgi - Kuramsal, Olgusal | To perform karyotype analysis of chromosome preparations and to recognize and interpret all human chromosomes | |
| PLO17 | Beceriler - Bilişsel, Uygulamalı | To interpret a scientific article and to learn how to write a paper |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | General information about bacteria. | Preparation of presentation. | Öğretim Yöntemleri: Anlatım, Beyin Fırtınası |
| 2 | Bacteria reproduction. | Preparation of presentation. | Öğretim Yöntemleri: Anlatım, Beyin Fırtınası |
| 3 | Cellular structures of bacteria. Intracellular structures. | Preparation of presentation. | Öğretim Yöntemleri: Anlatım, Beyin Fırtınası |
| 4 | External structures of bacteria. Surface extensions (ciliata, flagel, pilus). | Preparation of presentation. | Öğretim Yöntemleri: Anlatım, Beyin Fırtınası |
| 5 | Bacterial preparation and preparation of bacterial colonies. | Preparation of presentation. | Öğretim Yöntemleri: Anlatım, Beyin Fırtınası, Deney / Laboratuvar |
| 6 | Bacterial genome; DNA, RNA. | Preparation of presentation. | Öğretim Yöntemleri: Anlatım, Beyin Fırtınası |
| 7 | Regulation of gene functions in bacteria, operon. | Preparation of presentation. | Öğretim Yöntemleri: Anlatım, Beyin Fırtınası |
| 8 | Mid-Term Exam | Exam question preparation | Öğretim Yöntemleri: Anlatım, Beyin Fırtınası |
| 9 | Mutations in bacteria. | Preparation of presentation. | Öğretim Yöntemleri: Anlatım, Beyin Fırtınası |
| 10 | Bacteriophages, morphological structures, classification. | Preparation of presentation. | Öğretim Yöntemleri: Anlatım, Beyin Fırtınası |
| 11 | Life cycles of phages. | Preparation of presentation. | Öğretim Yöntemleri: Anlatım, Beyin Fırtınası |
| 12 | Transformation of genetic material between bacteria, Transformation. | Preparation of presentation. | Öğretim Yöntemleri: Anlatım, Beyin Fırtınası |
| 13 | Transformation of genetic material between bacteria, conjugation. | Preparation of presentation. | Öğretim Yöntemleri: Anlatım, Beyin Fırtınası |
| 14 | Transformation of genetic material between bacteria, transduction. | Preparation of presentation. | Öğretim Yöntemleri: Anlatım, Beyin Fırtınası |
| 15 | Plasmids. | Preparation of presentation. | Öğretim Yöntemleri: Anlatım, Beyin Fırtınası |
| 16 | Term Exams | Exam question preparation | Ölçme Yöntemleri: Yazılı Sınav |
| 17 | Term Exams | Exam question preparation | Ölçme Yöntemleri: Yazılı Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 4 | 56 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 3 | 42 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 4 | 8 | 32 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 2 | 2 |
| Final Exam | 1 | 2 | 2 |
| Total Workload (Hour) | 134 | ||
| Total Workload / 25 (h) | 5,36 | ||
| ECTS | 5 ECTS | ||