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Information
| Code | FAR524 |
| Name | Pharmacology of Smooth Muscle I |
| Term | 2024-2025 Academic Year |
| Term | Fall and Spring |
| Duration (T+A) | 2-0 (T-A) (17 Week) |
| ECTS | 5 ECTS |
| National Credit | 2 National Credit |
| Teaching Language | Türkçe |
| Level | Yüksek Lisans Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Prof. Dr. MEHMET ATA SEÇİLMİŞ |
| Course Instructor |
Prof. Dr. MEHMET ATA SEÇİLMİŞ
(A Group)
(Ins. in Charge)
|
Course Goal / Objective
Students will learn about smooth muscle physiology, the conduction pathways in smooth muscle, and the use of drugs that act on smooth muscle.
Course Content
Smooth muscle signaling pathways, perception and response of signals coming from outside or inside the smooth muscle cell by the smooth muscle cell, receptor types and signaling systems
Course Precondition
None
Resources
Akılcıl Tedavi Yönünden Tıbbi Farmakoloji, Editör: Prof. Dr. S. Oğuz Kayaalp
Notes
Goodman and Gilman's The Pharmacological Basis of Therapeutics
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | To have knowledge about smooth muscle conduction pathways |
| LO02 | To have knowledge about the processes by which smooth muscle cells perceive and respond to stimuli coming from outside or inside the smooth muscle cell. |
| LO03 | Knows the types of receptors and signaling pathways. |
| LO04 | To have knowledge about the side effects of drugs used in smooth muscle pharmacology |
| LO05 | To have knowledge about the mechanisms of action of drugs used in smooth muscle pharmacology |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Ability to use the concepts of pharmacology, pharmacokinetics and pharmacodynamics | 2 |
| PLO02 | Bilgi - Kuramsal, Olgusal | Establishes relationships between drug effects, mechanisms of action, and drug interactions | 2 |
| PLO03 | Bilgi - Kuramsal, Olgusal | Explains the side effects and toxic effects of drugs | 2 |
| PLO04 | Yetkinlikler - Alana Özgü Yetkinlik | Uses an experimental setup for an in vitro or in vivo pharmacological study | |
| PLO05 | Bilgi - Kuramsal, Olgusal | Follows scientific literature related to his/her field | 1 |
| PLO06 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Takes part in the design, maintenance and analysis of data of a research related to his/her field. | 1 |
| PLO07 | Bilgi - Kuramsal, Olgusal | Is aware of the importance of scientific research ethics. | 1 |
| PLO08 | Beceriler - Bilişsel, Uygulamalı | Expresses scientific thought analytically and establishes hypotheses. | |
| PLO09 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Takes part in the statistical evaluation of data. | |
| PLO10 | Beceriler - Bilişsel, Uygulamalı | Aware of the importance of rational drug use | 1 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Regulation of vascular smooth muscle tone - I | Pharmacology textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 2 | Regulation of vascular smooth muscle tone - II | Pharmacology textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 3 | Smooth muscle membrane receptors - I | Pharmacology textbooks | Öğretim Yöntemleri: Soru-Cevap, Anlatım |
| 4 | Smooth muscle membrane receptors - II | Pharmacology textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 5 | Ion channels in the vascular smooth muscle membrane - I | Pharmacology textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 6 | Ion channels in the vascular smooth muscle membrane - II | Pharmacology textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 7 | Signaling pathways in the vascular smooth muscle membrane - I | Pharmacology textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 8 | Mid-Term Exam | Pharmacology textbooks | Ölçme Yöntemleri: Ödev |
| 9 | Signaling pathways in the vascular smooth muscle membrane - II | Pharmacology textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 10 | Neuronal transmission in vascular smooth muscle - I | Pharmacology textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 11 | Neuronal transmission in vascular smooth muscle - II | Pharmacology textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 12 | Endothelium-dependent vasodilation - I | Pharmacology textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 13 | Endothelium-dependent vasodilation - II | Pharmacology textbooks | Öğretim Yöntemleri: Soru-Cevap, Anlatım |
| 14 | Literature reviews, article presentations and discussions | Pharmacology textbooks | Öğretim Yöntemleri: Soru-Cevap, Tartışma |
| 15 | Literature reviews, article presentations and discussions - II | Internet and literature databases | Öğretim Yöntemleri: Soru-Cevap, Tartışma |
| 16 | Term Exams | Pharmacology textbooks | Ölçme Yöntemleri: Yazılı Sınav |
| 17 | Term Exams | Pharmacology textbooks | Ölçme Yöntemleri: Sözlü Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 2 | 28 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 4 | 56 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 10 | 10 |
| Final Exam | 1 | 20 | 20 |
| Total Workload (Hour) | 114 | ||
| Total Workload / 25 (h) | 4,56 | ||
| ECTS | 5 ECTS | ||