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Information
| Code | Trans554 |
| Name | Cell Signaling Pathways |
| Term | 2024-2025 Academic Year |
| Semester | . Semester |
| Duration (T+A) | 3-0 (T-A) (17 Week) |
| ECTS | 5 ECTS |
| National Credit | 3 National Credit |
| Teaching Language | İngilizce |
| Level | Yüksek Lisans Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator |
Course Goal / Objective
Students learn and understand the signaling pathways and learn how to design experiments to study cell signaling
Course Content
Includes cell signaling receptors and pathways
Course Precondition
Basic molecular biology knowledge is necessary
Resources
Alberts, The Cell, Online resources
Notes
Online tools, journals and books
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Students can understand how a cell reacts after receiving a signal |
| LO02 | Students can design experiments to analyze signaling pathways |
| LO03 | Students learn the basic signaling pathways in a cell |
| LO04 | Students read and understand articles related to cell signaling |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Develops and deepens knowledge in the field of translational medicine to the proficiency level based on bachelor-level qualifications. | 3 |
| PLO02 | Bilgi - Kuramsal, Olgusal | Conceives the interdisciplinary interaction in which the field is related to translational medicine | 2 |
| PLO03 | Bilgi - Kuramsal, Olgusal | Knows the information technologies, technical equipment, and field-specific devices and instruments at the level required by the field of Translational Medicine. | 2 |
| PLO04 | Bilgi - Kuramsal, Olgusal | Knows statistics as a tool that is constantly used in studies in the field of Translational Medicine, and uses relevant software effectively. | 3 |
| PLO05 | Beceriler - Bilişsel, Uygulamalı | Uses of theoretical and practical knowledge within the field at a proficiency level. | |
| PLO06 | Beceriler - Bilişsel, Uygulamalı | Interprets the knowledge about the field by integrating the information gathered from different disciplines and formulates new knowledge. | 4 |
| PLO07 | Beceriler - Bilişsel, Uygulamalı | Makes necessary investigations by using tools, devices, and instruments required for knowledge and technologies about translational medicine and related disciplines at an advanced level; develops a new and creative solution (device, method, treatment, drug) for the problems. | 2 |
| PLO08 | Beceriler - Bilişsel, Uygulamalı | Solves the problem faced related to the field by using research methods. | 4 |
| PLO09 | Beceriler - Bilişsel, Uygulamalı | Plans and conducts an experimental study. | 1 |
| PLO10 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Takes responsibility and develops new strategic solutions as a team member in order to solve unexpected complex problems faced within the applications in the field, evaluates the results, and applies when necessary. | 1 |
| PLO11 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Conducts scientific studies in translational medicine and related fields independently or as a team member. | 3 |
| PLO12 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Publishes a scientific paper in a national journal or presents it at a scientific meeting. | |
| PLO13 | Yetkinlikler - Öğrenme Yetkinliği | Evaluates knowledge and skills acquired at proficiency level in the field with a critical approach and direct the learning. | 1 |
| PLO14 | Yetkinlikler - Öğrenme Yetkinliği | Applies the principles of advanced professional development and lifelong learning in the field of Translational Medicine. | 3 |
| PLO15 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Communicates current developments and studies within the field to both professional and non-professional groups systematically using written, oral and visual techniques by supporting quantitative and qualitative data. | 5 |
| PLO16 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Communicates and discusses orally, in writing, and visually with peers by using a foreign language at least at a level of European Language Portfolio B2 General Level. | 5 |
| PLO17 | Yetkinlikler - Alana Özgü Yetkinlik | Develops strategy, policy, and implementation plans on the issues related to the field and assess the findings within the frame of quality processes and ethics. | 3 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Introduction to receptors | Reading related book chapters and articles | Öğretim Yöntemleri: Tartışma |
| 2 | Receptors in different cells act different | Reading related book chapters and articles | Öğretim Yöntemleri: Tartışma |
| 3 | Phosphorylation of proteins | Reading related book chapters and articles | Öğretim Yöntemleri: Tartışma |
| 4 | Tyrosine kinase pathways | Reading related book chapters and articles | Öğretim Yöntemleri: Tartışma |
| 5 | Gene transcription through the cell signaling | Reading related book chapters and articles | Öğretim Yöntemleri: Tartışma |
| 6 | Inflammation induced pathways -1 | Reading related book chapters and articles | Öğretim Yöntemleri: Tartışma |
| 7 | Inflammation induced pathways-2 | Reading related book chapters and articles | Öğretim Yöntemleri: Problem Çözme |
| 8 | Mid-Term Exam | Reading related book chapters and articles | Ölçme Yöntemleri: Ödev |
| 9 | How to analyze a signaling pathway-1 | Reading related book chapters and articles | Öğretim Yöntemleri: Beyin Fırtınası |
| 10 | How to analyze a signaling pathway-2 | Reading related book chapters and articles | Öğretim Yöntemleri: Problem Çözme |
| 11 | How to analyze a signaling pathway-3 | Reading related book chapters and articles | Öğretim Yöntemleri: Problem Çözme |
| 12 | Signaling of Apoptosis | Reading related book chapters and articles | Öğretim Yöntemleri: Grup Çalışması |
| 13 | How to analyze apoptotic pathways | Reading related book chapters and articles | Öğretim Yöntemleri: Grup Çalışması |
| 14 | Signaling in cell cycle-1 | Reading related book chapters and articles | Öğretim Yöntemleri: Grup Çalışması |
| 15 | Signaling in cell cycle-2 | Reading related book chapters and articles | Öğretim Yöntemleri: Grup Çalışması |
| 16 | Term Exams | Reading related book chapters and articles | Ölçme Yöntemleri: Ödev |
| 17 | Term Exams | Reading related book chapters and articles | Ölçme Yöntemleri: Yazılı Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 3 | 42 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 4 | 56 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 2 | 12 | 24 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 2 | 2 |
| Final Exam | 1 | 1 | 1 |
| Total Workload (Hour) | 125 | ||
| Total Workload / 25 (h) | 5,00 | ||
| ECTS | 5 ECTS | ||