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Information
| Unit | ABDİ SÜTCÜ HEALTH SERVICES VOCATIONAL SCHOOL |
| Code | SHS229 |
| Name | Antibiotics and Their Mechanisms of Action |
| Term | 2025-2026 Academic Year |
| Semester | 3. Semester |
| Duration (T+A) | 2-0 (T-A) (17 Week) |
| ECTS | 4 ECTS |
| National Credit | 2 National Credit |
| Teaching Language | Türkçe |
| Level | Ön Lisans Dersi |
| Type | Normal |
| Label | CD Common Courses (Faculty/Vocational School/Conservatory) E Elective |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Doç. Dr. MERAL MİRALOĞLU |
| Course Instructor |
The current term course schedule has not been prepared yet.
|
Course Goal / Objective
In this course, the classification of antimicrobial agents, the mechanisms of action of antimicrobials, the mechanisms of resistance to antimicrobial agents and their clinical importance will be explained, and information will be given about antibiotic susceptibility tests applied in microbiology laboratories.
Course Content
What is an antibiotic? Basic antibiotic knowledge; classification of antibiotics, mechanisms of action, resistance mechanisms and sensitivity tests constitute the content of this course.
Course Precondition
None
Resources
Isenberg HD. Handbook of Clinical Microbiology Methods (Garcia LS ed., Başustaoğlu A, Yıldıran ŞT, trans.ed). Third Edition. Ankara, Atlas Kitapçılık. Volume 1, 2, 3.; 2013. Procop GW, Church DL, Hall GS, Janda WM, Koneman EW, Schreckenberger PC, Woods GL. Koneman Color Atlas and Diagnostic Microbiology Book (Us AD, Başustaoğlu AC trans.ed). 1st Edition. Ankara, Hipokrat Bookstore, 2017. Mandell, Douglas and Bennett?s Principles and Practice of Infectious Diseases. (Mandell GL, Bennett JE, Dolin R eds. 7th ed. Churchil Livingstone Elsevier, Philadelphia, 2010. Murray PR. Basic Medical Microbiology. (Us AD, Başustaoğlu AC ed). 1st Edition. Ankara, Güneş Tıp 4 Bookstores, 2018.
Notes
On-line and congress presentations
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Learn about antimicrobial agents |
| LO02 | Classify antimicrobial agents. |
| LO03 | Explain the mechanisms of action of antimicrobials and mechanisms of resistance to antimicrobials. |
| LO04 | Performs antibiotic susceptibility tests and interprets results. |
| LO05 | Know the clinical importance of the mechanisms of action of antimicrobials. |
| LO06 | Know the clinical importance of resistance mechanisms developing against antimicrobials. |
| LO07 | It raises awareness about rational antibiotic use. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Explains the basis of human normal structure and function | |
| PLO02 | Bilgi - Kuramsal, Olgusal | Defines disinfection, sterilization and hygiene. | 1 |
| PLO03 | Bilgi - Kuramsal, Olgusal | Recognizes laboratory tools- materials, and measurement methods. | |
| PLO04 | Bilgi - Kuramsal, Olgusal | Explains the procedures to be performed in these phases using detailed information on the preanalytical, analytical and postanalytical phases of measurements. | |
| PLO05 | Beceriler - Bilişsel, Uygulamalı | Receives and accepts biological materials taken from the patient, prepares them for analysis and ensures that they are preserved under appropriate conditions if necessary. | |
| PLO06 | Beceriler - Bilişsel, Uygulamalı | Performs internal and external quality control studies of the analyzes, analyzes patient samples after applying daily control procedures, checks the results and reports to the laboratory specialist. | |
| PLO07 | Beceriler - Bilişsel, Uygulamalı | Performs the calibration and maintenance of laboratory equipments, have them to be calibrated and maintained and monitored by authorized persons as needed, so that they work most efficiently | |
| PLO08 | Beceriler - Bilişsel, Uygulamalı | Determines inaduquaciesis in the laboratory | |
| PLO09 | Bilgi - Kuramsal, Olgusal | It provides coordination by reporting critical values to the clinician in the most appropriate and rapid way. | |
| PLO10 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | After graduation, he/she develops himself/herself and his/her career by following technological developments and critically evaluating the information he/she has learned with his/her own knowledge. | 2 |
| PLO11 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Having professional and ethical responsibility, they communicate well with colleagues, patients and physicians. | 2 |
| PLO12 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Uses at least one foreign language to follow developments in his field and to communicate with colleagues adequately. | 2 |
| PLO13 | Yetkinlikler - Öğrenme Yetkinliği | Takes measures regarding health, biosafety and occupational safety in the work environment. |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | General Information about Antibiotics | Repeating lectures | Öğretim Yöntemleri: Anlatım |
| 2 | Mechanisms of Action of Antibiotics-1 | Repeating lectures,ppt | Öğretim Yöntemleri: Anlatım |
| 3 | Antibiotics That Inhibit Cell Wall Synthesis | Repeating lectures,ppt | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 4 | Antibiotics That Inhibit Protein Synthesis | Repeating lectures,ppt,on line presentations | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 5 | Antibiotics Affecting Nucleic Acid Synthesis | Repeating lectures,ppt,on line presentations | Öğretim Yöntemleri: Soru-Cevap, Anlatım |
| 6 | Mechanisms of Action of Antibiotics-2 (Antibiotics that Disrupt Cell Membrane Function) | Repeating lectures,ppt,on line presentations | Öğretim Yöntemleri: Anlatım, Tartışma |
| 7 | Antibiotic Resistance Mechanisms-1 (Mechanisms of Resistance to Antibiotics Inhibiting Cell Wall Synthesis) | Repeating lectures,ppt,on line presentations | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 8 | Mid-Term Exam | Repeating lectures | Ölçme Yöntemleri: Yazılı Sınav |
| 9 | Antibiotic Resistance Mechanisms-2 (Mechanisms of Resistance to Antibiotics that Inhibit Protein Synthesis) | Repeating lectures,ppt,on line presentations | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Beyin Fırtınası |
| 10 | Antibiotic Susceptibility Tests | Repeating lectures,ppt | Öğretim Yöntemleri: Anlatım, Deney / Laboratuvar |
| 11 | Antibiotic Susceptibility Tests continue | Repeating lectures,ppt | Öğretim Yöntemleri: Deney / Laboratuvar |
| 12 | Mechanisms of action of antifungals | Repeating lectures,ppt,on line presentations | Öğretim Yöntemleri: Anlatım, Beyin Fırtınası |
| 13 | Mechanism of antiparasitic agents | Repeating lectures,ppt,on line presentations | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 14 | Rational use of antibiotics | Repeating lectures,ppt,on line presentations | Öğretim Yöntemleri: Anlatım, Tartışma, Beyin Fırtınası |
| 15 | Side effects and contraindications of antibiotics | Repeating lectures,ppt,on line presentations | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 16 | Term Exams | Repeating lectures | Ölçme Yöntemleri: Yazılı Sınav |
| 17 | Term Exams | Repeating lectures | Ölçme Yöntemleri: Yazılı Sınav, Ödev |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 2 | 28 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 4 | 56 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 1 | 2 | 2 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 1 | 1 |
| Final Exam | 1 | 1 | 1 |
| Total Workload (Hour) | 88 | ||
| Total Workload / 25 (h) | 3,52 | ||
| ECTS | 4 ECTS | ||