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Information
| Unit | INSTITUTE OF MEDICAL SCIENCES |
| BIOPHYSICS (MEDICINE) (PhD) | |
| Code | BFZ652 |
| Name | Advanced Muscle Biophysics From Molecule to Cell-2 (Z) |
| Term | 2025-2026 Academic Year |
| Term | Fall and Spring |
| Duration (T+A) | 2-2 (T-A) (17 Week) |
| ECTS | 6 ECTS |
| National Credit | 3 National Credit |
| Teaching Language | Türkçe |
| Level | Doktora Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Prof. Dr. AYKUT PELİT |
| Course Instructor |
The current term course schedule has not been prepared yet. Previous term groups and teaching staff are shown.
|
Course Goal / Objective
Mechanical properties of the muscles; Fenn effect, using chemical energy, heat and work, shortening and lengthening, isotonic and isometric contractions, cross bridges of myosin and actin, sliding filaments of the muscles, relations of the force-velocity and ATP kinetics.
Course Content
Skeletal muscles, Contractile forces, EMG
Course Precondition
There is no prerequisite for the lesson
Resources
Lecture notes (For Medical Faculty Students - İsmail Günay) Biophysics (Ferit Pehlivan) Biophysics (Gürbüz Çelebi) Internet Search
Notes
Internet Research
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Doing a muscle dissection independently. |
| LO02 | Learning a mechanisms of the skeletal muscles. |
| LO03 | Researching and making experiment of the skeletal muscles. |
| LO04 | The information learned systematic to mass transfer |
| LO05 | Learns measurement and measurable qualities |
| LO06 | Knows the stable-unstable state of the cell. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | To learn the basic information about the field | 1 |
| PLO02 | Bilgi - Kuramsal, Olgusal | To be able to establish experimental work in laboratory | |
| PLO03 | Bilgi - Kuramsal, Olgusal | To prepare a project proposal by itself | 3 |
| PLO04 | Bilgi - Kuramsal, Olgusal | To plan an experimental research | 2 |
| PLO05 | Bilgi - Kuramsal, Olgusal | To make a report as a result of the research | 3 |
| PLO06 | Bilgi - Kuramsal, Olgusal | To be able to interpret research findings | |
| PLO07 | Bilgi - Kuramsal, Olgusal | Having analytical thinking mechanism related to the field Accessing reliable information Creating and writing a research project Study and research based on ethic values | |
| PLO08 | Bilgi - Kuramsal, Olgusal | Ability to transfer the theoretical knowledge to the audience in a systematic way | 2 |
| PLO09 | Bilgi - Kuramsal, Olgusal | To have scientific thought systematic about the profession | |
| PLO10 | Bilgi - Kuramsal, Olgusal | Kendi başına bir proje önerisi hazırlayabilmek | 2 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Striated Muscles: From Molecules to Cells | Reference Books | Öğretim Yöntemleri: Tartışma |
| 2 | Energy Economy in the Actomyosin Interaction, Cross bridge movement, ATP hydrolysis | Reference Books | Öğretim Yöntemleri: Tartışma |
| 3 | Thick flaments and signifigance of the titin molecule, Contractile Characteristics of Sarcomeres, Fenn effect | Reference Books | Öğretim Yöntemleri: Soru-Cevap |
| 4 | Mechanic isolation the skeletal muscles, muscle dissection | Reference Books | Öğretim Yöntemleri: Tartışma |
| 5 | Contractile force measurements systems | Reference Books | Öğretim Yöntemleri: Alıştırma ve Uygulama |
| 6 | Converters and software systems | Reference Books | Öğretim Yöntemleri: Tartışma |
| 7 | Force-Length relation in the sarcomeres, Tropomyosin-Troponin interactions | Reference Books | Öğretim Yöntemleri: Soru-Cevap |
| 8 | Mid-Term Exam | works relevant sections | Ölçme Yöntemleri: Yazılı Sınav, Sözlü Sınav |
| 9 | Crossbridge and Non-crossbridge Contributions to Force in Shortening and Lengthening Muscle and Hill equation | Reference Books | Öğretim Yöntemleri: Soru-Cevap |
| 10 | Effects of temperature on the cross bridge. Mechanism of the muscle weakness. | Reference Books | Öğretim Yöntemleri: Tartışma |
| 11 | Isometric and isotonic contractiles, fast and slow twitch muscles | Reference Books | Öğretim Yöntemleri: Tartışma |
| 12 | Diabetic effetcs on the skeletal muscle | Reference Books | Öğretim Yöntemleri: Tartışma |
| 13 | EMG Methods and electrode types | Reference Books | Öğretim Yöntemleri: Tartışma |
| 14 | Skin surface electromyography and Integrated EMG. | Reference Books | Öğretim Yöntemleri: Tartışma |
| 15 | Data Analysis, drawing curves and discussion results. | Reference Books | Öğretim Yöntemleri: Soru-Cevap, Tartışma |
| 16 | Term Exams | works relevant sections | Ölçme Yöntemleri: Yazılı Sınav, Sözlü Sınav |
| 17 | Term Exams | works relevant sections | Ölçme Yöntemleri: Yazılı Sınav |
Assessment (Exam) Methods and Criteria
Current term shares have not yet been determined. Shares of the previous term are shown.
| Assessment Type | Midterm / Year Impact | End of Term / End of Year Impact |
|---|---|---|
| 1. Midterm Exam | 50 | 20 |
| 1. Oral Exam | 50 | 20 |
| General Assessment | ||
| Midterm / Year Total | 100 | 40 |
| 1. Final Exam | - | 60 |
| Grand Total | - | 100 |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 4 | 56 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 4 | 56 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 1 | 2 | 2 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 12 | 12 |
| Final Exam | 1 | 28 | 28 |
| Total Workload (Hour) | 154 | ||
| Total Workload / 25 (h) | 6,16 | ||
| ECTS | 6 ECTS | ||