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Information
| Unit | INSTITUTE OF MEDICAL SCIENCES |
| Code | FAR604 |
| Name | Biochemistry and Medical Significance of Polyphenols |
| Term | 2025-2026 Academic Year |
| Term | Fall and Spring |
| Duration (T+A) | 2-0 (T-A) (17 Week) |
| ECTS | 4 ECTS |
| National Credit | 2 National Credit |
| Teaching Language | Türkçe |
| Level | Doktora Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Prof. Dr. CEMİL GÖÇMEN |
| Course Instructor |
The current term course schedule has not been prepared yet.
|
Course Goal / Objective
It is aimed to teach the biochemistry of polyphenols, their use in experimental studies and their pathophysiology and to provide these evaluation skills for the development of new drugs in medical treatment.
Course Content
TO PROVIDE THE SKILLS TO USE THE IMPORTANCE AND ROLE OF PURINERGIC NEUROTRANSMISSION IN THE NERVOUS SYSTEM IN EXPERIMENTAL STUDIES BY CONSIDERING ITS PHYSIOPATHOLOGY
Course Precondition
NONE
Resources
Rasyonel Tedavi Yönünden Tıbbi Farmakoloji-Oğuz KAYAALP Katzung and Trevor’s Pharmacology Goodman &Gilman´s The Pharmacological Basis of Therapeutics
Notes
Scientific Literature
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Know the biochemistry of polyphenols and their contribution to medical treatment |
| LO02 | Knows the place and importance of polyphenols in antioxidant capacity |
| LO03 | Knows the interaction with free radicals |
| LO04 | Knows the experimental models related to the use of polyphenols in medical treatment. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Beceriler - Bilişsel, Uygulamalı | Discusses the mechanisms of action, side effects, and toxic effects of drugs. | 1 |
| PLO02 | Beceriler - Bilişsel, Uygulamalı | Explains drug effects, drug interactions and effects on organ systems with a systematic approach | 1 |
| PLO03 | Yetkinlikler - Alana Özgü Yetkinlik | Plans, implements and finalizes a scientific project | |
| PLO04 | Bilgi - Kuramsal, Olgusal | Recognize the research areas and research techniques of pharmacology | 1 |
| PLO05 | Yetkinlikler - Alana Özgü Yetkinlik | Comparatively examines and compiles scientific articles in the field of pharmacology. | 2 |
| PLO06 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Prepares the experimental setup for an in vitro or in vivo pharmacological study and solves problems. | 1 |
| PLO07 | Yetkinlikler - Alana Özgü Yetkinlik | He/she transforms the data obtained from the research project into a scientific research article. | |
| PLO08 | Yetkinlikler - Alana Özgü Yetkinlik | Evaluates drug use and its effects in society due to his/her knowledge about drugs. | |
| PLO09 | Bilgi - Kuramsal, Olgusal | Explain clinical phase studies in drug development. | |
| PLO10 | Beceriler - Bilişsel, Uygulamalı | Evaluates and interprets study data statistically. | |
| PLO11 | Beceriler - Bilişsel, Uygulamalı | contributes to public health with its awareness of rational drug use. | 1 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | INTRODUCTION TO THE PURINERGIC SYSTEM | READING BOOKS AND LITERATURE | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 2 | AUTONOMIC NEUROMUSCULAR TRANSMISSION CENTRAL NERVOUS SYSTEM PURINERGIC RECEPTORS AND THEIR SUBTYPES AND NEUROTRANSMISSION STORAGE, RELEASE AND DESTRUCTION OF ATP | READING BOOKS AND LITERATURE | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 3 | PATHOPHYSIOLOGY OF PURINERGIC NEUROTRANSMISSION IN AUTONOMIC GANGLIONS | Reading Books and Literature | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 4 | SENSORY NEURONS AND PURINERGIC NEUROTRANSMISSION | Reading Books and Literature | Öğretim Yöntemleri: Soru-Cevap, Anlatım |
| 5 | THE ROLE OF PURINERGIC NEUROTRANSMISSION IN BEHAVIORAL STUDIES | Reading Books and Literature | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 6 | NEURON-GLIA INTERACTIONS OF PURINERGIC NEUROTRANSMISSION | Reading Books and Literature | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 7 | THE ROLE OF PURINERGIC NEUROEFFECTOR TRANSMISSION IN EXOCRINE GLANDS AND ENDOCRINE CELLS | Reading Books and Literature | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 8 | Mid-Term Exam | Reading Books and Literature | Ölçme Yöntemleri: Ödev |
| 9 | THE ROLE OF PURINERGIC NEUROTRANSMISSION IN THE UROGENITAL SYSTEM AND PHYSIOPATHOLOGY | Reading Books and Literature | Öğretim Yöntemleri: Soru-Cevap, Anlatım |
| 10 | RELATIONSHIP OF PURINERGIC NEUROTRANSMISSION WITH COPPER CHELATORS | Reading Books and Literature | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 11 | THE ROLE AND PHYSIOPATHOLOGY OF PURINERGIC NEUROTRANSMISSION IN THE GASTROINTESTINAL SYSTEM | Reading Books and Literature | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 12 | MODULATION OF PURINERGIC NEUROTENSENSITION BY THIOL AMINOACIDS | Reading Books and Literature | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 13 | THE ROLE AND PHYSIOPATHOLOGY OF PURINERGIC NEUROTRANSMISSION IN THE GASTROINTESTINAL SYSTEM II | Reading Books and Literature | Öğretim Yöntemleri: Soru-Cevap, Anlatım |
| 14 | THE ROLE AND PHYSIOPATHOLOGY OF PURINERGIC NEUROTRANSMISSION IN THE RESPIRATORY SYSTEM | Reading Books and Literature | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 15 | REVIEW OF CLINICAL STUDIES ON PURINERGIC NEUROTRANSMISSION | Reading Books and Literature | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 16 | Term Exams | Reading Books and Literature | Ölçme Yöntemleri: Yazılı Sınav |
| 17 | Term Exams | Reading Books and Literature | Ölçme Yöntemleri: Sözlü Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 2 | 28 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 2 | 28 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 2 | 10 | 20 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 10 | 10 |
| Final Exam | 1 | 10 | 10 |
| Total Workload (Hour) | 96 | ||
| Total Workload / 25 (h) | 3,84 | ||
| ECTS | 4 ECTS | ||