TÜRKÇE
ENGLISH
Information
| Unit | INSTITUTE OF MEDICAL SCIENCES |
| MEDICAL BIOCHEMISTRY (MEDICINE) (MASTER) (WITH THESIS) | |
| Code | BİK553 |
| Name | Vitamins and Nutritional Biochemistry |
| Term | 2025-2026 Academic Year |
| Term | Fall and Spring |
| Duration (T+A) | 3-0 (T-A) (17 Week) |
| ECTS | 6 ECTS |
| National Credit | 3 National Credit |
| Teaching Language | Türkçe |
| Level | Yüksek Lisans Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | |
| Course Instructor |
The current term course schedule has not been prepared yet.
|
Course Goal / Objective
The aim of this course is to teach the structure, functions, roles in metabolic pathways, deficiency and toxicity-related clinical manifestations, and biochemical principles of dietary intake of vitamins.
Course Content
This course covers the biochemical characteristics of water- and fat-soluble vitamins, their roles in metabolic processes, enzyme reactions involving vitamins, mechanisms of absorption, transport, storage, and excretion, as well as their relevance in clinical biochemistry and nutrition science.
Course Precondition
pass the exam
Resources
Lİppincot
Notes
Murray, Bender et al. – Harper's Illustrated Biochemistry Gropper & Smith – Advanced Nutrition and Human Metabolism
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Classifies vitamins according to chemical structure |
| LO02 | Describes metabolic functions of each vitamin |
| LO03 | Identifies deficiency and toxicity states |
| LO04 | Explains absorption, transport, and storage mechanisms |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Yetkinlikler - Alana Özgü Yetkinlik | Explain the structure and function of the basic tissues of the body. | 1 |
| PLO02 | Belirsiz | Explain the structure and functions of the cell, their physiological mechanisms and bioelectrical events. | 1 |
| PLO03 | Belirsiz | Explain the structure and functions of biochemical molecules involved in metabolism. | 1 |
| PLO04 | Belirsiz | Know the structure and function of genetic material (DNA and RNA), gene expression, genome structure, nucleic acid metabolism and the use of DNA in medicine, the basic principles of heredity. |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Introduction: Definition and Classification of Vitamins | Absorption, Transport, and Storage of Vitamins | Öğretim Yöntemleri: Anlatım |
| 2 | Fat-Soluble Vitamins: General Features | Vitamin A: Structure, Function, and Metabolism | Öğretim Yöntemleri: Anlatım |
| 3 | Vitamin A Deficiency and Toxicity | Vitamin D: Biosynthesis and Physiological Role | Öğretim Yöntemleri: Anlatım |
| 4 | Clinical Aspects of Vitamin D | Vitamin E: Antioxidant Role and Clinical Importance | Öğretim Yöntemleri: Anlatım |
| 5 | Vitamin K: Coagulation and Other Functions | Water-Soluble Vitamins: General Features | Öğretim Yöntemleri: Anlatım |
| 6 | B1 (Thiamine): Role in Energy Metabolism | B2 (Riboflavin) and B3 (Niacin): Coenzyme Functions | Öğretim Yöntemleri: Anlatım |
| 7 | B5 (Pantothenic Acid) and B7 (Biotin) | Vitamin B6: Amino Acid Metabolism | Öğretim Yöntemleri: Anlatım |
| 8 | Mid-Term Exam | Ölçme Yöntemleri: Sözlü Sınav |
|
| 9 | B9 (Folate) and B12 (Cobalamin): Nucleic Acid Metabolism | B12 Absorption and Pernicious Anemia | Öğretim Yöntemleri: Anlatım |
| 10 | Vitamin C: Antioxidant and Enzymatic Functions | Clinical Biochemistry of Vitamin Deficiencies | Öğretim Yöntemleri: Anlatım |
| 11 | Vitamin Toxicities and Overdose Effects | Vitamin Analysis I (HPLC, ELISA) | Öğretim Yöntemleri: Anlatım |
| 12 | Vitamin Analysis II (LC-MS/MS, Spectrophotometry) | Vitamins and the Antioxidant System | Öğretim Yöntemleri: Anlatım |
| 13 | Interactions of Vitamins with Genetics and Epigenetics | Microbiota and Vitamin Bioavailability | Öğretim Yöntemleri: Anlatım |
| 14 | Dietary Sources of Vitamins | Vitamin Balance in Vegan and Vegetarian Diets | Öğretim Yöntemleri: Anlatım |
| 15 | Vitamin Requirements in Aging and Pregnancy | Vitamin Supplementation and Clinical Applications | Öğretim Yöntemleri: Anlatım |
| 16 | Term Exams | Ölçme Yöntemleri: Sözlü Sınav |
|
| 17 | Term Exams | Ölçme Yöntemleri: Yazılı Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 3 | 42 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 5 | 70 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 15 | 15 |
| Final Exam | 1 | 30 | 30 |
| Total Workload (Hour) | 157 | ||
| Total Workload / 25 (h) | 6,28 | ||
| ECTS | 6 ECTS | ||