Information
| Unit | INSTITUTE OF NATURAL AND APPLIED SCIENCES |
| BIOLOGY (PhD) | |
| Code | BY770 |
| Name | Regenerative Biology and Medical Applications |
| Term | 2025-2026 Academic Year |
| Term | Spring |
| Duration (T+A) | 3-0 (T-A) (17 Week) |
| ECTS | 6 ECTS |
| National Credit | 3 National Credit |
| Teaching Language | Türkçe |
| Level | Doktora Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Prof. Dr. SADIK DİNÇER |
| Course Instructor |
Dr. Öğr. Üyesi ÖZGECAN KAYALAR
(Bahar)
(A Group)
(Ins. in Charge)
|
Course Goal / Objective
Investigating the molecular mechanisms of regeneration in simple and complex organisms, the mechanisms involved in tissue repair and regeneration in different organ and tissue types, and the role of stem cells and tissue progenitors as endogenous repair support systems in disease and health. Understanding the relationship between aging and regeneration.
Course Content
Investigation of endogenous promoters and molecular mechanisms of regeneration in different organism organizations and different tissue types.
Course Precondition
None
Resources
Current publications
Notes
1. Principles of Regenerative Biology, Bruce M. Carlson, University of Michigan, Academic Press, Elsevier. 2. Regeneration Biology Explained, Sophia Curie, Publifye AS, ISBN: 9788235254269. 3. Alp Can, Stem Cell, Akademisyen Kitapevi 4. Prof. Dr. Adil M. Allahverdiyev, Basic Principles of Somatic and Stem Cell Culture Systems, Nobel Medical Bookstores 5. Current literature related to the subject
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Ability to apply knowledge in their field both theoretically and practically. |
| LO02 | Generating new knowledge by integrating existing in-depth knowledge in one's field. |
| LO03 | The ability to identify problems in their field, develop solutions, and solve the problem. |
| LO04 | Ability to evaluate concepts related to their field and conduct scientific analysis. |
| LO05 | Ability to make conceptual and applied contributions to scientific developments in their field. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Based on the qualifications of the graduate, it develops and deepens the current and advanced knowledge in the field with original thought and / or research at the level of expertise and reaches the original definitions that will bring innovation to the field. | |
| PLO02 | Bilgi - Kuramsal, Olgusal | Evaluates, uses and transfers new information in the field with a systematic approach. | 2 |
| PLO03 | Bilgi - Kuramsal, Olgusal | Develops a new idea, method, design and / or application that brings innovation to the field, or applies a known idea, method, design and / or application to a different field, researches, comprehends, designs and applies an original topic. | 3 |
| PLO04 | Bilgi - Kuramsal, Olgusal | Gains high level skills in using research methods in the field studies. | 3 |
| PLO05 | Bilgi - Kuramsal, Olgusal | Makes critical analysis, synthesis and evaluation of new and complex thoughts. | 2 |
| PLO06 | Bilgi - Kuramsal, Olgusal | Extends the boundaries of knowledge in the field by publishing at least one scientific paper in national and / or international refereed journals and / or producing or interpreting an original work. | 3 |
| PLO07 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Examines and develops the social relations and the norms that direct these relations from a critical point of view. | |
| PLO08 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Defends his / her original opinions in discussing the subjects in his / her field with experts, and establishes an effective communication showing his / her competence in his / her field. | 4 |
| PLO09 | Yetkinlikler - Öğrenme Yetkinliği | Introducing scientific, technological, social or cultural advances in the field; It contributes to the process of being a society of knowledge and sustaining it. | |
| PLO10 | Yetkinlikler - Öğrenme Yetkinliği | It contributes to the solution of social, scientific, cultural and ethical problems encountered in the field and supports the development of these values. | |
| PLO11 | Beceriler - Bilişsel, Uygulamalı | Develops new ideas and methods related to the field by using high level mental processes such as creative and critical thinking, problem solving and decision making. |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Introduction to regeneration: definitions and examples. | Reading current lecture notes and related articles, internet research. | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 2 | Developmental Signaling Pathways Associated with Cell Origin and Regeneration in Regenerative Systems | Reading current lecture notes and related articles, internet research. | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 3 | Epithelialization | Reading current lecture notes and related articles, internet research. | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 4 | The Role of Substrates and Ligands in Regeneration | Reading current lecture notes and related articles, internet research. | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Alıştırma ve Uygulama |
| 5 | Tissue Interactions in Regeneration | Reading current lecture notes and related articles, internet research. | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 6 | The Role of the Nervous System in Regeneration | Reading current lecture notes and related articles, internet research. | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 7 | Morphogenesis of Regenerating Structures | Reading current lecture notes and related articles, internet research. | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 8 | Mid-Term Exam | general review | Ölçme Yöntemleri: Sözlü Sınav, Ödev, Performans Değerlendirmesi |
| 9 | Regeneration and Aging | Reading current lecture notes and related articles, internet research. | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 10 | Environmental Influence on Regeneration | Reading current lecture notes and related articles, internet research. | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 11 | Stem Cells, Progenitors, Plasticity and Regeneration | Reading current lecture notes and related articles, internet research. | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 12 | Cell and Tissue Engineering and Regeneration | Reading current lecture notes and related articles, internet research. | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 13 | Stimulation of Regeneration - Limb Regeneration, Nervous System Regeneration | Reading current lecture notes and related articles, internet research. | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 14 | Stimulation of Regeneration - Lung, Liver, and Cardiac Regeneration | Reading current lecture notes and related articles, internet research. | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 15 | Student presentations and interactive discussions | Reading current lecture notes and related articles, internet research. | Öğretim Yöntemleri: Soru-Cevap, Tartışma, Alıştırma ve Uygulama |
| 16 | Term Exams | general review | Ölçme Yöntemleri: Yazılı Sınav, Sözlü Sınav, Performans Değerlendirmesi |
| 17 | Term Exams | oral/writing exam | Ölçme Yöntemleri: Yazılı Sınav, Sözlü Sınav, Performans Değerlendirmesi |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 3 | 42 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 5 | 70 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 15 | 15 |
| Final Exam | 1 | 30 | 30 |
| Total Workload (Hour) | 157 | ||
| Total Workload / 25 (h) | 6,28 | ||
| ECTS | 6 ECTS | ||