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Information
| Unit | INSTITUTE OF MEDICAL SCIENCES |
| PEDIATRIC ONCOLOGY (MASTER) (WITH THESIS) | |
| Code | PEDO528 |
| Name | Molecular Pathology of Childhood Cancers |
| Term | 2026-2027 Academic Year |
| Term | Fall and Spring |
| Duration (T+A) | 2-2 (T-A) (17 Week) |
| ECTS | 5 ECTS |
| National Credit | 3 National Credit |
| Teaching Language | Türkçe |
| Level | Yüksek Lisans Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | |
| Course Instructor |
The current term course schedule has not been prepared yet.
|
Course Goal / Objective
Understanding the Molecular Pathology of Childhood Cancers
Course Content
Molecular Pathology of Childhood Cancers
Course Precondition
Arrive in class on time and prepared.
Resources
To be shared with the student before the lesson.
Notes
To be shared with the student before the lesson.
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | They learn that it is characterized by unique chromosomal translocations, fusion genes, and gene amplifications. |
| LO02 | The molecular pathology of childhood cancers recognizes that they differ from those in adults. |
| LO03 | Understands the importance of molecular pathology in the treatment of childhood cancers. |
| LO04 | What more can we learn about the moleculer pathology? |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | - | They gain expertise in donor selection. | 1 |
| PLO02 | - | During the stem cell transplantation process, the most suitable graft is selected. | 2 |
| PLO03 | - | It lists the characteristics of donors according to the type of stem cell transplant. | 2 |
| PLO04 | - | It explains the concepts of haploidentical and allogeneic transplantation. | |
| PLO05 | - | It lists the principles for collecting stem cells from cord blood. | 1 |
| PLO06 | - | This describes the steps involved in collecting CD34 cells from peripheral blood. | |
| PLO07 | - | It describes the necessary conditions for collecting stem cells from bone marrow. | 1 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | The aim is molecular pathology of childhood cancers. | Preparation from the given lecture notes. | Öğretim Yöntemleri: Soru-Cevap, Tartışma |
| 2 | Molecular pathology and etiology of childhood cancers. | Preparation from the given lecture notes. | Öğretim Yöntemleri: Soru-Cevap, Tartışma |
| 3 | Differences from adults | Preparation from the given lecture notes. | Öğretim Yöntemleri: Soru-Cevap, Tartışma |
| 4 | Basic Genetic Mechanisms | Preparation from the given lecture notes. | Öğretim Yöntemleri: Soru-Cevap, Tartışma |
| 5 | Unique Translocations | Preparation from the given lecture notes. | Öğretim Yöntemleri: Soru-Cevap, Tartışma |
| 6 | Molecular Profiling and Therapy | Preparation from the given lecture notes. | Öğretim Yöntemleri: Soru-Cevap, Tartışma |
| 7 | Targeted Therapies | Preparation from the given lecture notes. | Öğretim Yöntemleri: Soru-Cevap, Tartışma |
| 8 | Mid-Term Exam | Prepare the same way | Ölçme Yöntemleri: Sözlü Sınav |
| 9 | Early diagnosis and treatment process in childhood cancers. | Preparation from the given lecture notes. | Öğretim Yöntemleri: Soru-Cevap, Tartışma |
| 10 | Small, round, blue cell tumors | Preparation from the given lecture notes. | Öğretim Yöntemleri: Soru-Cevap, Tartışma |
| 11 | Its use in solid tumors such as leukemia, lymphoma, and neuroblastoma. | Preparation from the given lecture notes. | Öğretim Yöntemleri: Soru-Cevap, Tartışma |
| 12 | Chromosomal translocations, inversions, and amplification of proto-oncogenes that control cell growth. | Preparation from the given lecture notes. | Öğretim Yöntemleri: Soru-Cevap, Tartışma |
| 13 | MYCN amplification in neuroblastoma or RB1 gene deletion in retinoblastoma | Preparation from the given lecture notes. | Öğretim Yöntemleri: Soru-Cevap, Tartışma |
| 14 | summary of the topic | Preparation from the given lecture notes. | Öğretim Yöntemleri: Soru-Cevap, Tartışma |
| 15 | importance of the topic | Preparation from the given lecture notes. | Öğretim Yöntemleri: Soru-Cevap, Tartışma |
| 16 | Term Exams | Preperation from the given lacture notes | Ölçme Yöntemleri: Sözlü Sınav |
| 17 | Term Exams | Peparation from the given lecture notes. | Ölçme Yöntemleri: Sözlü Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 10 | 6 | 60 |
| Out of Class Study (Preliminary Work, Practice) | 10 | 6 | 60 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 3 | 3 | 9 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 1 | 1 |
| Final Exam | 1 | 1 | 1 |
| Total Workload (Hour) | 131 | ||
| Total Workload / 25 (h) | 5,24 | ||
| ECTS | 5 ECTS | ||