TÜRKÇE
ENGLISH
Information
| Unit | INSTITUTE OF MEDICAL SCIENCES |
| PEDIATRIC ONCOLOGY (MASTER) (WITH THESIS) | |
| Code | PEDO530 |
| Name | |
| Term | 2026-2027 Academic Year |
| Term | Fall and Spring |
| Duration (T+A) | 2-1 (T-A) (17 Week) |
| ECTS | 5 ECTS |
| National Credit | 2.5 National Credit |
| Teaching Language | Türkçe |
| Level | Yüksek Lisans Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | |
| Course Instructor |
The current term course schedule has not been prepared yet.
|
Course Goal / Objective
Understanding the gene transfer applications in pediatric cancers
Course Content
Application of gene transfer methods in treatment of childhood cancers
Course Precondition
Knows the pathophysiology of cancer
Resources
Pizzo & Poplack,Principles and practice of pediatric oncology, 2025, 9th ed
Notes
Online books and journals
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | defines gene therapy |
| LO02 | lists methodologies used in gene therapy |
| LO03 | defines the ethics in gene therapy |
| LO04 | defines safety in gene therapy |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | - | They gain expertise in donor selection. | 1 |
| PLO02 | - | During the stem cell transplantation process, the most suitable graft is selected. | 1 |
| PLO03 | - | It lists the characteristics of donors according to the type of stem cell transplant. | |
| PLO04 | - | It explains the concepts of haploidentical and allogeneic transplantation. | 1 |
| PLO05 | - | It lists the principles for collecting stem cells from cord blood. | 1 |
| PLO06 | - | This describes the steps involved in collecting CD34 cells from peripheral blood. | 1 |
| PLO07 | - | It describes the necessary conditions for collecting stem cells from bone marrow. |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | definition of gene therapy | recommended resources | Öğretim Yöntemleri: Anlatım |
| 2 | viral vectors | recommended resources | Öğretim Yöntemleri: Anlatım |
| 3 | oncolytic virotherapy | recommended resources | Öğretim Yöntemleri: Anlatım |
| 4 | suicide gene therapy | recommended resources | Öğretim Yöntemleri: Anlatım |
| 5 | Visiting molecular genetic laboratory | recommended resources | Öğretim Yöntemleri: Alıştırma ve Uygulama |
| 6 | Immune system mechanisms | recommended resources | Öğretim Yöntemleri: Anlatım |
| 7 | CAR-T cell therapy | recommended resources | Öğretim Yöntemleri: Proje Temelli Öğrenme |
| 8 | Mid-Term Exam | lecture notes and recommended resources | Ölçme Yöntemleri: Performans Değerlendirmesi |
| 9 | Delivery systems in gene therapy | recommended resources | Öğretim Yöntemleri: Grup Çalışması |
| 10 | Safety in gene therapy | recommended resources | Öğretim Yöntemleri: Grup Çalışması |
| 11 | Manufacturing and cost | recommended resources | Öğretim Yöntemleri: Tartışma |
| 12 | Gene therapy in solid tumors | recommended resources | Öğretim Yöntemleri: Anlatım |
| 13 | Cancer gene therapy in Türkiye | recommended resources | Öğretim Yöntemleri: Anlatım |
| 14 | Cellular therapies | recommended resources | Öğretim Yöntemleri: Anlatım |
| 15 | Seminar-Invited speaker | recommended resources | Öğretim Yöntemleri: Anlatım |
| 16 | Term Exams | lecture notes and recommended resources | Ölçme Yöntemleri: Performans Değerlendirmesi |
| 17 | Term Exams | lecture notes and recommended resources | Ölçme Yöntemleri: Proje / Tasarım |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 8 | 10 | 80 |
| Out of Class Study (Preliminary Work, Practice) | 2 | 2 | 4 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 6 | 6 | 36 |
| Mid-term Exams (Written, Oral, etc.) | 2 | 2 | 4 |
| Final Exam | 1 | 1 | 1 |
| Total Workload (Hour) | 125 | ||
| Total Workload / 25 (h) | 5,00 | ||
| ECTS | 5 ECTS | ||