TÜRKÇE
ENGLISH
Information
| Code | ECS523 |
| Name | Microbial Antibiotic Synthesis |
| Term | 2022-2023 Academic Year |
| Semester | 9. Semester |
| Duration (T+A) | 1-1 (T-A) (17 Week) |
| ECTS | 3 ECTS |
| National Credit | 1 National Credit |
| Teaching Language | Türkçe |
| Level | Lisans Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Dr. Öğr. Üyesi ABDURRAHMAN AYGÜL |
| Course Instructor |
Didem YILMAZ ORAL
(A Group)
(Ins. in Charge)
|
Course Goal / Objective
It aims to provide students with theoretical knowledge and basic practical skills on the production of antibiotics from bacterial/fungal microorganisms by traditional methods.
Course Content
Isolation of bacterial/fungal microorganisms from environmental foci such as soil, surface water, wild plants, Bacterial - fungal co-cultures, obtaining antibiotics by natural means, fermentation
Course Precondition
None.
Resources
None.
Notes
None.
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Exemplifies microorganisms that naturally produce antibiotics |
| LO02 | Isolate Streptomyces griseus from the environmen using agar plate |
| LO03 | Isolate Penicillium chrysogenum from the environmen using agar plate |
| LO04 | Counts the parts of simple bioreactors |
| LO05 | Explain the fermentation concept with examples |
| LO06 | Counts the process of preparing a bioreactor in sterile steps for antibiotic synthesis. |
| LO07 | Explain penicillin isolation from the fermentation environment in the bioreactor. |
| LO08 | Explain the isolation of streptomycin from the fermentation environment in the bioreactor. |
| LO09 | Detects the sensitivity of antibiotics isolated using disc diffusion test |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Have sufficient knowledge in pharmaceutical field and develop the knowledge. | 5 |
| PLO02 | Bilgi - Kuramsal, Olgusal | Comprehends professional knowledge with ethical responsibility through current laws and legislation. | |
| PLO03 | Beceriler - Bilişsel, Uygulamalı | Provides consultancy service to patients, community and health care personnel and evaluates advanced knowledge and skills with a critical approach. | 3 |
| PLO04 | Beceriler - Bilişsel, Uygulamalı | Possessing the knowledge of historical and current developments in the field of Pharmacy, monitoring, evaluation and application of scientific and evidence-based data, and adopting lifelong learning. | 3 |
| PLO05 | Beceriler - Bilişsel, Uygulamalı | Have the knowledge and skills to help provide patient-oriented pharmacy applications and individualized pharmaceutical care by learning the basics of Clinical Pharmacy, | |
| PLO06 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Takes a role in the evaluation and analysis of the events and cases related to the development of pharmacy profession and education. | |
| PLO07 | Yetkinlikler - Öğrenme Yetkinliği | Integrates and develops professional knowledge via different disciplines and uses the acquired knowledge to improve the health level and quality of life of the community. | 3 |
| PLO08 | Yetkinlikler - Öğrenme Yetkinliği | Use effectively the concepts and applications of basic sciences and basic medical sciences in the field of medicine and pharmacy and update the information. | 4 |
| PLO09 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Communicates effectively in writing and speaking. | |
| PLO10 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Practices the profession in accordance with Atatürk's principles and reforms, equipped with universal knowledge, uses Turkish correctly and knows at least one foreign language. | |
| PLO11 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Be an example to society withexternal appearance, demeanor, attitude and behavior for the other professionals and society and with professional identity | |
| PLO12 | Yetkinlikler - Alana Özgü Yetkinlik | Have knowledge about health policies and health economics, pharmacy management and define the problems in pharmaceutical field. | 4 |
| PLO13 | Yetkinlikler - Alana Özgü Yetkinlik | Interprets information about current health and treatment problems and attends meeting on related matters . Plays an active role in community health. | |
| PLO14 | Yetkinlikler - Alana Özgü Yetkinlik | Acquires basic information about diseases, makes decisions about the drugs used in treatment in accordance with rational drug use. |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | History of antibiotics | Related publications and books | Öğretim Yöntemleri: Anlatım, Grup Çalışması, Deney / Laboratuvar, Proje Temelli Öğrenme |
| 2 | Bacteria - fungal joint cultures | Related publications and books | Öğretim Yöntemleri: Anlatım, Grup Çalışması, Deney / Laboratuvar, Proje Temelli Öğrenme |
| 3 | Environmental microorganisms and antibiotic synthesis | Related publications and books | Öğretim Yöntemleri: Anlatım, Grup Çalışması, Deney / Laboratuvar, Proje Temelli Öğrenme |
| 4 | Simple bioreactor design and installation | Related publications and books | Öğretim Yöntemleri: Anlatım, Grup Çalışması, Deney / Laboratuvar, Proje Temelli Öğrenme |
| 5 | Fermentation | Related publications and books | Öğretim Yöntemleri: Anlatım, Grup Çalışması, Deney / Laboratuvar, Proje Temelli Öğrenme |
| 6 | Isolation | Related publications and books | Öğretim Yöntemleri: Anlatım, Grup Çalışması, Deney / Laboratuvar, Proje Temelli Öğrenme |
| 7 | Quantification | Related publications and books | Öğretim Yöntemleri: Anlatım, Grup Çalışması, Deney / Laboratuvar, Proje Temelli Öğrenme |
| 8 | Mid-Term Exam | Subject repetition | Ölçme Yöntemleri: Yazılı Sınav |
| 9 | Streptomyces griseus isolation for obtaining streptomycin | Related publications and books | Öğretim Yöntemleri: Anlatım, Grup Çalışması, Deney / Laboratuvar, Proje Temelli Öğrenme |
| 10 | Obtaining streptomycin 1 | Related publications and books | Öğretim Yöntemleri: Anlatım, Grup Çalışması, Deney / Laboratuvar, Proje Temelli Öğrenme |
| 11 | Obtaining streptomycin 2 | Related publications and books | Öğretim Yöntemleri: Anlatım, Grup Çalışması, Deney / Laboratuvar, Proje Temelli Öğrenme |
| 12 | Penicillium chrysogenum isolation for obtaining penicillin | Related publications and books | Öğretim Yöntemleri: Anlatım, Grup Çalışması, Deney / Laboratuvar, Proje Temelli Öğrenme |
| 13 | Obtaining penicillin 1 | Related publications and books | Öğretim Yöntemleri: Anlatım, Grup Çalışması, Deney / Laboratuvar, Proje Temelli Öğrenme |
| 14 | Obtaining penicillin 2 | Related publications and books | Öğretim Yöntemleri: Anlatım, Grup Çalışması, Deney / Laboratuvar, Proje Temelli Öğrenme |
| 15 | Activity determinations of synthesized antibiotics | Related publications and books | Öğretim Yöntemleri: Anlatım, Grup Çalışması, Deney / Laboratuvar, Proje Temelli Öğrenme |
| 16 | Term Exams | Subject repetition | Ölçme Yöntemleri: Yazılı Sınav |
| 17 | Term Exams | Subject repetition | Ölçme Yöntemleri: Yazılı Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 2 | 28 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 2 | 28 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 1 | 2 | 2 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 6 | 6 |
| Final Exam | 1 | 16 | 16 |
| Total Workload (Hour) | 80 | ||
| Total Workload / 25 (h) | 3,20 | ||
| ECTS | 3 ECTS | ||