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Information
| Code | Trans616 |
| Name | Translation from Cancer Biology |
| Term | 2023-2024 Academic Year |
| Semester | . Semester |
| Duration (T+A) | 3-0 (T-A) (17 Week) |
| ECTS | 5 ECTS |
| National Credit | 3 National Credit |
| Teaching Language | İngilizce |
| Level | Doktora Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator |
Course Goal / Objective
Addressing cancer biology information with a Translational Medicine perspective and developing new ideas
Course Content
Students learn the relationship of cancer with the microenvironment, escape mechanisms from the immune system and hypoxic conditions, the behavior of cancer stem cells, and comprehend the mechanisms of resistance to treatment. By examining the current literature in cancer biology, he/she understands how the effects of a potential drug molecule that can be used in the diagnosis and treatment of cancer are examined and prepares a project outline by developing a research question.
Course Precondition
Basic knowledge of human anatomy and molecular biology
Resources
Scopus and WOS articles
Notes
Translational Medicine Journals
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Understands the cellular level of cancer development |
| LO02 | Learns the types pf cancer metastasis |
| LO03 | Learns the principles to image cancer metastasis |
| LO04 | Understand the principles of the targeted therapy discovery principles for cancer treatment |
| LO05 | Can read, understand and analyze the research articles related with cancer biology and translational medicine |
| LO06 | Starting with cancer biology, students can develop an idea that can be used for cancer diagnosis or treatment. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Develops and deepens the current and advanced level knowledge of translational medicine via unique thoughts or researches at a level of proficiency, find out original definitions that will bring innovation in the field of translational medicine. | 3 |
| PLO02 | Bilgi - Kuramsal, Olgusal | Conceives the interdisciplinary interactions related to translational medicine; analyzes synthesizes and evaluates original and new thoughts. | 2 |
| PLO03 | Bilgi - Kuramsal, Olgusal | Explains the usage of tool, devices and instruments requiered for knowledge and technologies about translational medicine and its related disciplines. | 2 |
| PLO04 | Bilgi - Kuramsal, Olgusal | Defines frequently used statistical methods in translational medicine and related disciplines, uses statistical softwares effectively. | 1 |
| PLO05 | Beceriler - Bilişsel, Uygulamalı | Uses both theoretical and practical knowledge at an advanced level in the studies related to translational medicine. | 1 |
| PLO06 | Beceriler - Bilişsel, Uygulamalı | Develops a new thoughts, method and designment/application which brings innovation in translational medicine or implements a known thoughts, method and designment/application in different fields, investigates, comprehends, designs, adapts, implements an original topic. | 5 |
| PLO07 | Beceriler - Bilişsel, Uygulamalı | Writes the report of his/her research which he/she participated, | 1 |
| PLO08 | Beceriler - Bilişsel, Uygulamalı | Makes necessary investigations by using tool, devices and instrument required for knowledge and technologies about translational medicine and related disciplines at an advanced level, develops a new and creative solution (device, method, treatment, drug) for the problems. | 3 |
| PLO09 | Beceriler - Bilişsel, Uygulamalı | Uses statistical software in the field of Translational Medicine effectively, chooses statistical methods correctly, calculates and interprets correctly. | 1 |
| PLO10 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Maintains the organization of Translational Medicine laboratories and develops solutions in case of encountering unforeseen complex situations during laboratory working hours. | 1 |
| PLO11 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Conducts scientific studies in translational medicine and related fields independently or as a team member. | 3 |
| PLO12 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Writes the report of his/her research in which he/she participated, publishes in a national or international reputed journal (indexing in SCI, SCI-Expanded, SSCI, or AHCI), and presents it at scientific meetings. | 1 |
| PLO13 | Yetkinlikler - Öğrenme Yetkinliği | Follows evidence-based practices and conducts research on professional practices that will create evidence in their field. | 2 |
| PLO14 | Yetkinlikler - Öğrenme Yetkinliği | Applies the principles of advanced professional development and lifelong learning in the field of Translational Medicine. | 3 |
| PLO15 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Communicate current developments and studies within the field to both professional and non-professional groups systematically using written, oral and visual techniques by supporting with quantitative and qualitative data. | 2 |
| PLO16 | Bilgi - Kuramsal, Olgusal | Learns how to teach a concept, subject, phenomenon or case related to Translational Medicine. | |
| PLO17 | Belirsiz | Communicate and discuss orally, in written and visually with peers by using a foreign language at least at a level of European Language Portfolio B2 General Level. | 2 |
| PLO18 | Yetkinlikler - Alana Özgü Yetkinlik | Audit the data gathering, interpretation, implementation and announcement stages by taking into consideration the cultural, scientific, and ethic values and uses these issues for social strategy, implementation plans and frame of quality processes. | 3 |
| PLO19 | Yetkinlikler - Alana Özgü Yetkinlik | Knows the importance of ethical principles and ethical committees for the individual and society, acts ethically. | 2 |
| PLO20 | Yetkinlikler - Alana Özgü Yetkinlik | Increases the awareness of society about translational medicine. |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Cancer Biology-1 | Article read in the related subject | Öğretim Yöntemleri: Soru-Cevap |
| 2 | Cancer Biology-2 | Article read in the related subject | Öğretim Yöntemleri: Soru-Cevap |
| 3 | Mechanisms of cancer metastasis | Article read in the related subject | Öğretim Yöntemleri: Grup Çalışması |
| 4 | Student Presentations of the mechanisms of metastasis | Presentation skills | Öğretim Yöntemleri: Grup Çalışması |
| 5 | Understanding Metastasis | Self study of other groups' presentations | Öğretim Yöntemleri: Tartışma |
| 6 | Imaging Cancer and metastasis-1 | Article read | Öğretim Yöntemleri: Bireysel Çalışma |
| 7 | Imaging cancer and metastasis-2 | Article read | Öğretim Yöntemleri: Soru-Cevap |
| 8 | Mid-Term Exam | Self study | Ölçme Yöntemleri: Yazılı Sınav, Performans Değerlendirmesi |
| 9 | Targeted therapies in cancer-1 | Article read | Öğretim Yöntemleri: Soru-Cevap, Tartışma |
| 10 | Targeted therapies in cancer-2 | Homeworks | Öğretim Yöntemleri: Tartışma |
| 11 | Article criticism-1 | Article read before class | Öğretim Yöntemleri: Tartışma |
| 12 | Article criticism-2 | Article read before class | Öğretim Yöntemleri: Grup Çalışması |
| 13 | Student article presentations | preparing presentation | Öğretim Yöntemleri: Proje Temelli Öğrenme |
| 14 | Development of an idea in the cancer translational science-1 | literature review in a selected cancer model | Öğretim Yöntemleri: Proje Temelli Öğrenme |
| 15 | Development of an idea in the cancer translational science-12 | Preparing a presentation for their idea | Öğretim Yöntemleri: Proje Temelli Öğrenme |
| 16 | Term Exams | Homework | Ölçme Yöntemleri: Ödev |
| 17 | Term Exams | Homework | Ölçme Yöntemleri: Ödev |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 3 | 42 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 3 | 42 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 12 | 12 |
| Final Exam | 1 | 18 | 18 |
| Total Workload (Hour) | 114 | ||
| Total Workload / 25 (h) | 4,56 | ||
| ECTS | 5 ECTS | ||