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Information
| Code | ECS506 |
| Name | Pharmacovigilance and Drug Interactions |
| Term | 2024-2025 Academic Year |
| Semester | 10. Semester |
| Duration (T+A) | 2-0 (T-A) (17 Week) |
| ECTS | 3 ECTS |
| National Credit | 2 National Credit |
| Teaching Language | Türkçe |
| Level | Lisans Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Didem YILMAZ ORAL |
| Course Instructor |
1 2 |
Course Goal / Objective
The aim of this course is to learn the mechanisms of action involving drug-drug and drug-food interactions, and to examine some interactions.
Course Content
Definitions and concepts related to pharmacovigilance, basic concepts of drug interactions, pharmacokinetic and pharmacodynamic mechanisms of drug interactions, most common drug interactions and case examples.
Course Precondition
None.
Resources
Bertram, G., Katzung, S., Masters, B., Antony, J. T. (2010). Basic and Clinical Pharmacology, 11 th edition, Mc Graw Hill, Lange, Boston. Kayaalp S.O., (2012) Akılcıl Tedavi Yönünden Tıbbi Farmakoloji Pelikan Yayıncılık, Ankara. Publications and websites.
Notes
Bertram, G., Katzung, S., Masters, B., Antony, J. T. (2010). Basic and Clinical Pharmacology, 11 th edition, Mc Graw Hill, Lange, Boston. Kayaalp S.O., (2012) Akılcıl Tedavi Yönünden Tıbbi Farmakoloji Pelikan Yayıncılık, Ankara. Publications and websites.
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Students can explain the general concepts of drug interactions. |
| LO02 | Students can recognize adverse drug reaction. |
| LO03 | Students can identify and evaluate drug-disease interactions. |
| LO04 | Students can identify and evaluate drug-drug and drug-food interactions. |
| LO05 | Students have skills in monitoring, recording and announcing drug interactions. |
| LO06 | Students can define the basic concepts and processes related to pharmacovigilance. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Have sufficient knowledge in pharmaceutical field and develop the knowledge. | 4 |
| PLO02 | Bilgi - Kuramsal, Olgusal | Comprehends professional knowledge with ethical responsibility through current laws and legislation. | 2 |
| PLO03 | Beceriler - Bilişsel, Uygulamalı | Provides consultancy service to patients, community and health care personnel and evaluates advanced knowledge and skills with a critical approach. | 4 |
| PLO04 | Beceriler - Bilişsel, Uygulamalı | Possessing the knowledge of historical and current developments in the field of Pharmacy, monitoring, evaluation and application of scientific and evidence-based data, and adopting lifelong learning. | 1 |
| PLO05 | Beceriler - Bilişsel, Uygulamalı | Have the knowledge and skills to help provide patient-oriented pharmacy applications and individualized pharmaceutical care by learning the basics of Clinical Pharmacy, | 2 |
| PLO06 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Takes a role in the evaluation and analysis of the events and cases related to the development of pharmacy profession and education. | 2 |
| PLO07 | Yetkinlikler - Öğrenme Yetkinliği | Integrates and develops professional knowledge via different disciplines and uses the acquired knowledge to improve the health level and quality of life of the community. | |
| PLO08 | Yetkinlikler - Öğrenme Yetkinliği | Use effectively the concepts and applications of basic sciences and basic medical sciences in the field of medicine and pharmacy and update the information. | 4 |
| PLO09 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Communicates effectively in writing and speaking. | 3 |
| PLO10 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Practices the profession in accordance with Atatürk's principles and reforms, equipped with universal knowledge, uses Turkish correctly and knows at least one foreign language. | 3 |
| PLO11 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Be an example to society withexternal appearance, demeanor, attitude and behavior for the other professionals and society and with professional identity | |
| PLO12 | Yetkinlikler - Alana Özgü Yetkinlik | Have knowledge about health policies and health economics, pharmacy management and define the problems in pharmaceutical field. | 3 |
| PLO13 | Yetkinlikler - Alana Özgü Yetkinlik | Interprets information about current health and treatment problems and attends meeting on related matters . Plays an active role in community health. | 2 |
| PLO14 | Yetkinlikler - Alana Özgü Yetkinlik | Acquires basic information about diseases, makes decisions about the drugs used in treatment in accordance with rational drug use. | 3 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Definitions of pharmacovigilance and general concepts | Reading the related literature and textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 2 | History of pharmacovigilance and applications in the world and in Turkey | Reading the related literature and textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 3 | Drug Interactions - Introduction | Reading the related literature and textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 4 | Pharmacokinetic Drug Interactions (Absorption and Distribution phase) | Reading the related literature and textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 5 | Pharmacokinetic Drug Interactions (Metabolism and Excretion phase) | Reading the related literature and textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 6 | Pharmacodynamic Interactions | Reading the related literature and textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 7 | Pharmacodynamic Interactions (Synergism and Potentialism) | Reading the related literature and textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 8 | Mid-Term Exam | Reading the related literature and textbooks | Ölçme Yöntemleri: Ödev, Performans Değerlendirmesi |
| 9 | Examples of important drug interactions | Reading the related literature and textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 10 | Student presentations (Azole group antifungals and calcium channel blockers) | Reading the related literature and textbooks | Öğretim Yöntemleri: Soru-Cevap, Tartışma, Grup Çalışması |
| 11 | Student presentations (Monoamine oxidase inhibitor and lithium) | Reading the related literature and textbooks | Öğretim Yöntemleri: Soru-Cevap, Tartışma, Grup Çalışması |
| 12 | Student presentations (warfarin and nonsteroidal anti-inflammatory drugs) | Reading the related literature and textbooks | Öğretim Yöntemleri: Soru-Cevap, Tartışma, Grup Çalışması |
| 13 | Student presentations (digoxin) | Reading the related literature and textbooks | Öğretim Yöntemleri: Soru-Cevap, Tartışma, Grup Çalışması |
| 14 | Student presentations (Selective serotonin reuptake inhibitors) | Reading the related literature and textbooks | Öğretim Yöntemleri: Soru-Cevap, Tartışma, Grup Çalışması |
| 15 | General overview and case reports | Reading the related literature and textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 16 | Term Exams | Reading the related literature and textbooks | Ölçme Yöntemleri: Yazılı Sınav |
| 17 | Term Exams | Reading the related literature and textbooks | Ölçme Yöntemleri: Yazılı Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 2 | 28 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 2 | 28 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 6 | 6 |
| Final Exam | 1 | 16 | 16 |
| Total Workload (Hour) | 78 | ||
| Total Workload / 25 (h) | 3,12 | ||
| ECTS | 3 ECTS | ||