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Information
| Code | BMM0075 |
| Name | Lab On A Chip Systems |
| Term | 2024-2025 Academic Year |
| Term | Fall |
| Duration (T+A) | 3-0 (T-A) (17 Week) |
| ECTS | 6 ECTS |
| National Credit | 3 National Credit |
| Teaching Language | Türkçe |
| Level | Doktora Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | |
| Course Instructor |
Prof. Dr. MUTLU AVCI
(A Group)
(Ins. in Charge)
|
Course Goal / Objective
Understanding Lab on a chip systems and learning the design methods of electronic parts.
Course Content
Lab on a chip biological and chemical analysis systems with CMOS electronic circuit.
Course Precondition
No prerequisite
Resources
Yehya H. Ghallab, Wael Badawy, Lab-on-a-Chip: Techniques, Circuits, and Biomedical Applications, ARTECH HOUSE Press, 2010, ISBN 13: 978-1-59693-418-4.
Notes
Ebrahim Ghafar-Zadeh, Mohamad Sawan, CMOS Capacitive Sensors for Lab-on-Chip Applications, Springer 2010, SBN 978-90-481-3726-8 e-ISBN 978-90-481-3727-5.
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Expresses the application areas of Lab-on-a-chip systems. |
| LO02 | Knows Lab-on-a-chip systems. |
| LO03 | Designs Lab-on-a-chip and CMOS circuit integration. |
| LO04 | Knows the seperation mechanism of microorganisms. |
| LO05 | Uses cell seperation systems. |
| LO06 | Designs neural activity sensing systems. |
| LO07 | Expresses, thermal, electrical and optical sensing systems. |
| LO08 | Designs compact systems for biochemical analysis. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | To be able to reach new solutions by applying current and advanced technical approaches of mathematics, science and engineering sciences to current scientific problems encountered in the field of medicine and medical technologies. | 5 |
| PLO02 | Yetkinlikler - Öğrenme Yetkinliği | Having knowledge of the literature related to a sub-discipline of biomedical engineering, defining and modeling current problems, and being a specialist in that discipline. | 4 |
| PLO03 | Beceriler - Bilişsel, Uygulamalı | Analyzing data, making theoretical and simulation based designs, designing experiments and interpreting the results. | |
| PLO04 | Beceriler - Bilişsel, Uygulamalı | Developing researched contemporary techniques, software, hardware and computational tools for engineering applications. | 4 |
| PLO05 | Beceriler - Bilişsel, Uygulamalı | To be able to analyze and design a process in line with a defined target. | |
| PLO06 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | To be able to carry out scientific studies with medical doctors and members of other disciplines from an engineering point of view. | 3 |
| PLO07 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Expressing one's own findings orally and in writing, clearly and concisely, writing conference and journal papers. | |
| PLO08 | Yetkinlikler - Öğrenme Yetkinliği | To be able to improve oneself by embracing the importance of lifelong learning and by following the developments in science-technology and contemporary issues. | |
| PLO09 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | The ability to act independently, set priorities and be creative. | |
| PLO10 | Yetkinlikler - Alana Özgü Yetkinlik | Being aware of national and international contemporary scientific and social problems in the field of Biomedical Engineering. | 2 |
| PLO11 | Yetkinlikler - Alana Özgü Yetkinlik | To be able to evaluate the contribution of engineering solutions to problems in medicine, medical technologies and health in a global and social context. | 3 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Introduction to Lab-on-a-chip systems | Not required | Öğretim Yöntemleri: Anlatım |
| 2 | Microfluidics | Reading the related parts from the textbook and/or additional reference book | Öğretim Yöntemleri: Anlatım |
| 3 | Thermal, electrical and optic sensors. | Reading the related part from the textbook | Öğretim Yöntemleri: Anlatım |
| 4 | Cell structures, properties and models | Reading the related part from the textbook | Öğretim Yöntemleri: Anlatım |
| 5 | Electromechnanics of particles | Reading the related part from the textbook | Öğretim Yöntemleri: Anlatım |
| 6 | Cell manipulating fields | Reading the related part from the textbook | Öğretim Yöntemleri: Anlatım |
| 7 | Sensors and sensing mechanisms | Reading the related parts from the textbook and/or additional reference book | Öğretim Yöntemleri: Anlatım |
| 8 | Mid-Term Exam | Repetation of the topics and problem solving | Ölçme Yöntemleri: Yazılı Sınav |
| 9 | CMOS based Lab-on-a-chip | Reading the related part from the textbook | Öğretim Yöntemleri: Anlatım |
| 10 | Microorganism detection and manipulation | Reading the related part from the textbook | Öğretim Yöntemleri: Anlatım |
| 11 | Neuronal activity detection | Reading the related part from the textbook | Öğretim Yöntemleri: Anlatım |
| 12 | Cytometry applications | Reading the related part from the textbook | Öğretim Yöntemleri: Anlatım |
| 13 | eFET, DeFET and ISFET | Reading the related scientific papers | Öğretim Yöntemleri: Anlatım |
| 14 | Readout circuits | Reading the related parts from the textbook and/or additional reference book | Öğretim Yöntemleri: Anlatım |
| 15 | pH sensing appli cation | Reading the related part from the textbook | Öğretim Yöntemleri: Anlatım |
| 16 | Term Exams | Repetation of the topics and problem solving | Ölçme Yöntemleri: Yazılı Sınav |
| 17 | Term Exams | Repetation of the topics and problem solving | Ölçme Yöntemleri: Yazılı Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 3 | 42 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 5 | 70 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 15 | 15 |
| Final Exam | 1 | 30 | 30 |
| Total Workload (Hour) | 157 | ||
| Total Workload / 25 (h) | 6,28 | ||
| ECTS | 6 ECTS | ||