BİO609 Cancer Biology and Genetics (Z)

6 ECTS - 4-0 Duration (T+A)- . Semester- 4 National Credit

Information

Code BİO609
Name Cancer Biology and Genetics (Z)
Term 2024-2025 Academic Year
Semester . Semester
Duration (T+A) 4-0 (T-A) (17 Week)
ECTS 6 ECTS
National Credit 4 National Credit
Teaching Language Türkçe
Level Doktora Dersi
Type Normal
Mode of study Yüz Yüze Öğretim
Catalog Information Coordinator Prof. Dr. HÜSNÜ ÜMİT LÜLEYAP


Course Goal / Objective

To be able to define cancer, to be able to define the relationship between cell cycle to know and define pathways with effective mechanism and genes

Course Content

Introduction of Cancer, Cell cycle and cancer, Development of cancer, Cancer pathways I, Cancer pathways II, Oncogenes, Tumor suppressor genes, Repair Mechanisms on Cancer, Epigenetic I, Epigenetics II, Invasion and Metastasis I, Invasion and Metastasis II, Apoptosis, Cell Aging

Course Precondition

To have taken Medical Genetics and Gene Genome Proteom courses

Resources

1-Moleküler Genetiğin Esasları, Ümit Lüleyap Akademisyen Kitabevi 2. baskı. 2020 2- The Biology of Cancer Robert A, Weinberg 2. Edition Garland Sciences. 3-The Cell. A Molecular Approach, G:M. Cooper Sewenth Edition Snauer

Notes

1-Moleküler Genetiğin Esasları, Ümit Lüleyap Akademisyen Kitabevi 2. baskı. 2020 2- The Biology of Cancer Robert A, Weinberg 2. Edition Garland Sciences. 3-The Cell. A Molecular Approach, G:M. Cooper Sewenth Edition Snauer


Course Learning Outcomes

Order Course Learning Outcomes
LO01 Is able to define cancer with its own expression and is able to associate with cell cycle
LO02 Is able to define the development of cancer, and associate with cell repair mechanisms
LO03 Is able to relate epigenetic mechanisms to cancer
LO04 Is able to describe the mechanisms of invasion and metastasis
LO05 Is able to associate disregulation of apoptosis and cell aging mechanisms with cancer


Relation with Program Learning Outcome

Order Type Program Learning Outcomes Level
PLO01 Bilgi - Kuramsal, Olgusal To make and interpret Medical Genetics, Molecular Genetics and Cytogenetic analyzes 3
PLO02 Bilgi - Kuramsal, Olgusal To have information about genetic diseases
PLO03 Bilgi - Kuramsal, Olgusal To have knowledge of Molecular Cell Biology 4
PLO04 Bilgi - Kuramsal, Olgusal To apply fluorescence in-situ hybridization (FISH) technique 1
PLO05 Bilgi - Kuramsal, Olgusal To make DNA isolation and PCR of all kinds of tissue 2
PLO06 Bilgi - Kuramsal, Olgusal To make cell culture of all kinds of tissue (blood, amniotic fluid, chorionic villus biopsy)
PLO07 Bilgi - Kuramsal, Olgusal To do cytogenetic analysis by recognizing human chromosomes separately 2
PLO08 Bilgi - Kuramsal, Olgusal To make QF-PCR and to interpret the results 1
PLO09 Bilgi - Kuramsal, Olgusal To have the knowledge and skills to teach Medical Biology and Genetics Courses in Medical Faculties
PLO10 Bilgi - Kuramsal, Olgusal To write and implement a research project on his/her own 2
PLO11 Bilgi - Kuramsal, Olgusal To write an article by collecting the information obtained at the end of the research
PLO12 Yetkinlikler - Öğrenme Yetkinliği To organize laboratory courses of Medical Biology and Genetics courses at undergraduate level


Week Plan

Week Topic Preparation Methods
1 Introduction of Cancer Slide preparation Öğretim Yöntemleri:
Soru-Cevap, Tartışma
2 Cell cycle and cancer Slide preparation Öğretim Yöntemleri:
Soru-Cevap, Tartışma, Alıştırma ve Uygulama
3 Development of cancer Slide preparation Öğretim Yöntemleri:
Soru-Cevap
4 Cancer pathways I Slide preparation Öğretim Yöntemleri:
Tartışma
5 Cancer pathways II Slide preparation Öğretim Yöntemleri:
Soru-Cevap, Tartışma
6 Oncogenes Slide preparation Öğretim Yöntemleri:
Tartışma, Soru-Cevap
7 Tumor suppressor genes Slide preparation Öğretim Yöntemleri:
Soru-Cevap, Tartışma
8 Mid-Term Exam Preparation of multiple-choice questions Ölçme Yöntemleri:
Ödev, Sözlü Sınav, Yazılı Sınav
9 Repair Mechanisms on Cancer Slide preparation Öğretim Yöntemleri:
Soru-Cevap, Tartışma
10 Epigenetic I Slide preparation Öğretim Yöntemleri:
Tartışma
11 Epigenetics II Slide preparation Öğretim Yöntemleri:
Tartışma
12 Invasion and Metastasis I Slide preparation Öğretim Yöntemleri:
Tartışma
13 Invasion and Metastasis II Slide preparation Öğretim Yöntemleri:
Tartışma
14 Apoptosis Slide preparation Öğretim Yöntemleri:
Tartışma
15 Cell Aging Slide preparation Öğretim Yöntemleri:
Tartışma
16 Term Exams Preparation of multiple-choice questions Öğretim Yöntemleri:
Tartışma
17 Term Exams Preparation of multiple-choice questions Ölçme Yöntemleri:
Ödev, Sözlü Sınav, Yazılı Sınav


Student Workload - ECTS

Works Number Time (Hour) Workload (Hour)
Course Related Works
Class Time (Exam weeks are excluded) 14 4 56
Out of Class Study (Preliminary Work, Practice) 14 4 56
Assesment Related Works
Homeworks, Projects, Others 3 9 27
Mid-term Exams (Written, Oral, etc.) 1 3 3
Final Exam 1 3 3
Total Workload (Hour) 145
Total Workload / 25 (h) 5,80
ECTS 6 ECTS

Update Time: 26.09.2024 11:58