Information
Code | BİO607 |
Name | Cell Cycle and Control |
Term | 2024-2025 Academic Year |
Semester | . Semester |
Duration (T+A) | 3-0 (T-A) (17 Week) |
ECTS | 5 ECTS |
National Credit | 3 National Credit |
Teaching Language | Türkçe |
Level | Doktora Dersi |
Type | Normal |
Mode of study | Yüz Yüze Öğretim |
Catalog Information Coordinator | Prof. Dr. AYFER PAZARBAŞI |
Course Goal / Objective
To present and tell cell signaling, cell cycle, cell death, cell renewal and molecular basis of cancer biolgy.
Course Content
Cell signaling, Molecules and receptors of signaling, Intracelular signaling with hydrophobic and hydrophylic receptors, the role of cell skeleton in cell signaling, Signal network, Cell cycle, Eukaryotic cell cycle, Regulators of cell cycle, Cell death and renewal, Programed cell death, Embryonic stem cells and therapeutic cloning, cancer, causes and progress of cancer, tumor viruses, oncogenes, tumor suppressor genes, molecular approach in cancer treatment.
Course Precondition
There is no precondition for this lesson.
Resources
Kasap H.(Ed.), M. Kasap, O. Demirhan, D. Alptekin, Ü. Lüleyap, A. Pazarbaşı, A.Irfan Güzel. Tıbbi Biyoloji ve Genetik, Nobel Kitabevi; ISBN: 978-605-397-059-0, 421-435, Adana (2016).
Notes
Cooper GM, Hausman RE. 2007. The Cell, A Molecular Approach. Fourth Ed., ASM Press, Washington DC.
Course Learning Outcomes
Order | Course Learning Outcomes |
---|---|
LO01 | The student explains basic cell signal molecules, reseptors and signaling pathways. |
LO02 | The student tells eukaryotic cell cycle and molecular control mechanisms. |
LO03 | The student outlines programed and other cell death pathways. |
LO04 | The student expreses the relationship between cell skeleton and signaling. |
LO05 | The student describes stem cells with every aspect. |
LO06 | The student outlines therapeutic cloning. |
LO07 | The student explains the relationship between cancer progress and tumor viruses, oncogenes and tumor suppressor genes. |
LO08 | The student expreses the significance of signaling in development and differentiation. |
LO09 | The student outlines normal cellular pathways. |
LO10 | The student comprehends intracellular signaling pathways. |
LO11 | The student explains the molecular aspects of cancer treatment. |
Relation with Program Learning Outcome
Order | Type | Program Learning Outcomes | Level |
---|---|---|---|
PLO01 | Bilgi - Kuramsal, Olgusal | To make and interpret Medical Genetics, Molecular Genetics and Cytogenetic analyzes | 1 |
PLO02 | Bilgi - Kuramsal, Olgusal | To have information about genetic diseases | 3 |
PLO03 | Bilgi - Kuramsal, Olgusal | To have knowledge of Molecular Cell Biology | 5 |
PLO04 | Bilgi - Kuramsal, Olgusal | To apply fluorescence in-situ hybridization (FISH) technique | |
PLO05 | Bilgi - Kuramsal, Olgusal | To make DNA isolation and PCR of all kinds of tissue | |
PLO06 | Bilgi - Kuramsal, Olgusal | To make cell culture of all kinds of tissue (blood, amniotic fluid, chorionic villus biopsy) | |
PLO07 | Bilgi - Kuramsal, Olgusal | To do cytogenetic analysis by recognizing human chromosomes separately | |
PLO08 | Bilgi - Kuramsal, Olgusal | To make QF-PCR and to interpret the results | |
PLO09 | Bilgi - Kuramsal, Olgusal | To have the knowledge and skills to teach Medical Biology and Genetics Courses in Medical Faculties | |
PLO10 | Bilgi - Kuramsal, Olgusal | To write and implement a research project on his/her own | |
PLO11 | Bilgi - Kuramsal, Olgusal | To write an article by collecting the information obtained at the end of the research | |
PLO12 | Yetkinlikler - Öğrenme Yetkinliği | To organize laboratory courses of Medical Biology and Genetics courses at undergraduate level |
Week Plan
Week | Topic | Preparation | Methods |
---|---|---|---|
1 | Eukaryotic cell cycle | Literature review and reading the subject | Öğretim Yöntemleri: Anlatım, Tartışma |
2 | Regulation of eukaryotic cell cycle | Literature review and reading the subject | Öğretim Yöntemleri: Anlatım, Tartışma |
3 | The stages of division | Literature review and reading the subject | Öğretim Yöntemleri: Anlatım, Grup Çalışması |
4 | Meiosis and fertilization | Literature review and reading the subject | Öğretim Yöntemleri: Anlatım, Tartışma |
5 | Molecules and receptors of cell signaling | Literature review and reading the subject | Öğretim Yöntemleri: Anlatım, Beyin Fırtınası |
6 | Types of cell signaling | Literature review and reading the subject | Öğretim Yöntemleri: Anlatım, Tartışma |
7 | Intracellular signaling pathways | Literature review and reading the subject | Öğretim Yöntemleri: Anlatım, Tartışma |
8 | Mid-Term Exam | Preparation a presentation | Ölçme Yöntemleri: Performans Değerlendirmesi |
9 | Cell skeleton and signaling | Literature review and reading the subject | Öğretim Yöntemleri: Anlatım, Grup Çalışması |
10 | Cell signaling in development and differentiation. | Literature review and reading the subject | Öğretim Yöntemleri: Anlatım, Tartışma |
11 | Programed cell death and regulation of programed cell death | Literature review and reading the subject | Öğretim Yöntemleri: Anlatım, Tartışma |
12 | The relationship between cancer and cell signaling | Literature review and reading the subject | Öğretim Yöntemleri: Anlatım, Tartışma |
13 | The relationship between cancer and cell cycle | Literature review and reading the subject | Öğretim Yöntemleri: Anlatım, Tartışma |
14 | Normal cellular pathways | Literature review and reading the subject | Öğretim Yöntemleri: Anlatım, Tartışma |
15 | Stem cells and protecting adult tissues | Literature review and reading the subject | Öğretim Yöntemleri: Anlatım, Beyin Fırtınası |
16 | Term Exams | Preparation multiple choice and classical questions | Ölçme Yöntemleri: Yazılı Sınav, Performans Değerlendirmesi |
17 | Term Exams | Preparation multiple choice and classical questions | Ölçme Yöntemleri: Yazılı Sınav, Performans Değerlendirmesi |
Student Workload - ECTS
Works | Number | Time (Hour) | Workload (Hour) |
---|---|---|---|
Course Related Works | |||
Class Time (Exam weeks are excluded) | 14 | 3 | 42 |
Out of Class Study (Preliminary Work, Practice) | 14 | 3 | 42 |
Assesment Related Works | |||
Homeworks, Projects, Others | 3 | 15 | 45 |
Mid-term Exams (Written, Oral, etc.) | 1 | 2 | 2 |
Final Exam | 1 | 2 | 2 |
Total Workload (Hour) | 133 | ||
Total Workload / 25 (h) | 5,32 | ||
ECTS | 5 ECTS |