TÜRKÇE
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Information
| Code | BİO529 |
| Name | Nutrigenetics |
| Term | 2024-2025 Academic Year |
| Term | Fall and Spring |
| Duration (T+A) | 3-0 (T-A) (17 Week) |
| ECTS | 5 ECTS |
| National Credit | 3 National Credit |
| Teaching Language | Türkçe |
| Level | Yüksek Lisans Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Prof. Dr. AYFER PAZARBAŞI |
| Course Instructor |
Prof. Dr. AYFER PAZARBAŞI
(A Group)
(Ins. in Charge)
|
Course Goal / Objective
Causing the student to gain knowledge of the relationship of gene and diet, nutritional genetics and epigenetics, single nucleotid polymorphisms, gene examples and disease risks.
Course Content
Beeing able to know and explain the relationship of gene and diet, nutritional genetics and epigenetics, single nucleotid polymorphisms and disease risks, diet, methylation and cancer, Diabetes, obesity, osteoporosis, hypertension genetics, dietetics approach to modify cardiovascular biological markers, lactose intolerance, folate metabolism and related diseases, lipid metabolism and known polymorphisms and genes.
Course Precondition
There no precondition for this lesson.
Resources
Coşkun T. Nutritional genomics. Çocuk Sağlığı ve Hastalıkları Dergisi 2007; 50: 1-56.
Notes
Gündoğdu AK, KARAHAN AG. Nutrigenomik Teknolojileri. GIDA 2008; 33 (4): 183-191.
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | The student defines the relationship between gene and diet. |
| LO02 | The student understands the relationship of single nucleotid polymorphisms and disease risks. |
| LO03 | The student understands the relationship of diet and cancer. |
| LO04 | The student understands the relationship of diet and epigenetics. |
| LO05 | The student defines obesity genetics. |
| LO06 | The student expresses osteoporosis genetics. |
| LO07 | The student explains hypertension genetics and lipid metabolism. |
| LO08 | The student clarifies dietetics approach to modify cardiovascular biological markers. |
| LO09 | The student infers about folate metabolism and related diseases. |
| LO10 | The student looks over ferrum homeostasis and hemochromatosis. |
| LO11 | The student recalls the genetics of lactose intolerance. |
| LO12 | The student clarifies known polymorphisms and gene examples. |
| LO13 | The student explains diabetes genetics. |
| LO14 | The student realizes nutrition and healthy life. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | To comprehend the structure and functions of cells and organelles which constitute the basic structure of life | 1 |
| PLO02 | Bilgi - Kuramsal, Olgusal | To recognize the functions of tissue and organ systems | |
| PLO03 | Bilgi - Kuramsal, Olgusal | To examine the structure of genetic material | 1 |
| PLO04 | Bilgi - Kuramsal, Olgusal | To recognize genetic diseases and genes that cause these diseases | 2 |
| PLO05 | Bilgi - Kuramsal, Olgusal | To learn the structure of genes | 1 |
| PLO06 | Bilgi - Kuramsal, Olgusal | To define chromosome and gene mutations | 1 |
| PLO07 | Bilgi - Kuramsal, Olgusal | To classify heredity forms (autosomal dominant, autosomal recessive, gender-dependent dominant and recessive inheritance models) | 1 |
| PLO08 | Bilgi - Kuramsal, Olgusal | To use molecular and cytogenetic analysis | 1 |
| PLO09 | Bilgi - Kuramsal, Olgusal | To be able to explain the numerical and structural anomalies of autosomal and sex chromosomes | |
| PLO10 | Bilgi - Kuramsal, Olgusal | To make DNA isolation from all kinds of tissues | |
| PLO11 | Bilgi - Kuramsal, Olgusal | To prepare PCR | |
| PLO12 | Bilgi - Kuramsal, Olgusal | To make and interpret agarose and polyacrylamide gel electrophoresis | |
| PLO13 | Bilgi - Kuramsal, Olgusal | To measure the obtained DNA on the spectrophotometer | |
| PLO14 | Bilgi - Kuramsal, Olgusal | To apply and interpret QF-PCR technique | |
| PLO15 | Bilgi - Kuramsal, Olgusal | To make cell culture from blood, amnion, chorionic villus biopsy specimens and to obtain chromosome preparation | |
| PLO16 | Bilgi - Kuramsal, Olgusal | To perform karyotype analysis of chromosome preparations and to recognize and interpret all human chromosomes | |
| PLO17 | Beceriler - Bilişsel, Uygulamalı | To interpret a scientific article and to learn how to write a paper |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | The relationship of gene and diet, Nutritional genetics and epigenetics | Literature rewiev and reading | |
| 2 | Nutrition and Healthy Life. | Literature rewiev and reading | |
| 3 | Obesity genetics. | Literature rewiev and reading | |
| 4 | Genetics of cardiovascular diseases and Dietetics approach | Literature rewiev and reading | |
| 5 | Genetic variations at hypertension | Literature rewiev and reading | |
| 6 | The relationship of Cancer, Methylation and Diet | Literature rewiev and reading | |
| 7 | SNP's and disease risks | Literature rewiev and reading | |
| 8 | Mid-Term Exam | Preparing a presentation | |
| 9 | Lactose intolerance | Literature rewiev and reading | |
| 10 | Genetics of osteoporosis and bone health | Literature rewiev and reading | |
| 11 | Folate metabolism, Neural tube defect, Down syndrome | Literature rewiev and reading | |
| 12 | Ferrum homeostasis, hemochromatosis | Literature rewiev and reading | |
| 13 | SNP examples for Lipid metabolism | Literature rewiev and reading | |
| 14 | Genetics of diabetes | Literature rewiev and reading | |
| 15 | Known polymorphisms for gene examples | Literature rewiev and reading | |
| 16 | Term Exams | Preparing multiple choice and classical tests | |
| 17 | Term Exams | Preparing multiple choice and classical tests |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 3 | 42 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 3 | 42 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 2 | 8 | 16 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 12 | 12 |
| Final Exam | 1 | 18 | 18 |
| Total Workload (Hour) | 130 | ||
| Total Workload / 25 (h) | 5,20 | ||
| ECTS | 5 ECTS | ||