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Information
| Unit | INSTITUTE OF NATURAL AND APPLIED SCIENCES |
| BIOTECHNOLOGY (MASTER) (WITH THESIS) (INTERDISCIPLINARY) | |
| Code | BT570 |
| Name | Dosage Forms Enabling Transcutaneous Drug Administration |
| Term | 2025-2026 Academic Year |
| Term | Fall |
| Duration (T+A) | 3-0 (T-A) (17 Week) |
| ECTS | 6 ECTS |
| National Credit | 3 National Credit |
| Teaching Language | Türkçe |
| Level | Lisansüstü Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Dr. Öğr. Üyesi ESRA DEMİRTÜRK |
| Course Instructor |
The current term course schedule has not been prepared yet.
|
Course Goal / Objective
The purpose of this course is to provide information about Transdermal Drug Delivery Systems for providing systemic treatment through the skin.
Course Content
General structure of transdermal drug delivery (TDD) systems, advantages and disadvantages, formulation design, production technologies, in vitro/in vivo characterization, evaluation of TDD formulations
Course Precondition
To be a graduate of the Faculty of Pharmacy, Faculty of Veterinary Medicine, Food Engineering, Faculty of Fisheries, Department of Molecular Biology and Genetics, and Department of Biology.
Resources
Mechanism of Transdermal Drug Delivery, R.S. Potts, R.H. Guy, 1997. Ita, K. (2016). Transdermal Drug Delivery: Principles and Practice. Wiley.
Notes
Williams, A., & Rathbone, M. J. (Eds.). (2003). Transdermal and Topical Drug Delivery: From Theory to Clinical Practice. Pharmaceutical Press.
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | In this course, students learn the definition of transdermal drug delivery systems (TTD) and the criteria for selecting candidate drugs. |
| LO02 | In this course, students learn formulation design by knowing the general structure of TTD. |
| LO03 | In this course, students learn TTD production technologies and compare these technologies according to the candidate drug. |
| LO04 | Learn how to examine scientific research on the subject and present an article. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Based on undergraduate level qualifications, they develop their knowledge at the level of expertise in the same or a different field. | |
| PLO02 | Bilgi - Kuramsal, Olgusal | Knows the ethical rules to be considered while obtaining biotechnological products. | 1 |
| PLO03 | Beceriler - Bilişsel, Uygulamalı | To identifiy the interdisciplinary interaction of the field and to solve use of the methods. | |
| PLO04 | Beceriler - Bilişsel, Uygulamalı | Interpret the knowledge gained in the field by integrating the information from different disciplines and creates new information | 2 |
| PLO05 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Develops new strategic approaches for solving complex problems that are encountered in applications related to the field. | 2 |
| PLO06 | Yetkinlikler - Öğrenme Yetkinliği | To teach the social, scientific, cultural and ethical values during the collection, interpretation, implementation and announcement of the data related to the field. | 2 |
| PLO07 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | To solve the problems encountered in the field and cominicate by using research methods. | |
| PLO08 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Establishes functional interaction by using strategic decision-making processes in solving the problems encountered in the field. | 2 |
| PLO09 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | He / she defends his / her original opinions in discussing the subjects in his / her field and establishes an effective communication showing his / her competence in the field. | 2 |
| PLO10 | Yetkinlikler - Alana Özgü Yetkinlik | To gain the ability to develop and deepen the knowledge in the field of biotechnology |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Structure of the skin and absorption through the skin | Preparation of visual slides related to the subject | Öğretim Yöntemleri: Soru-Cevap |
| 2 | Definition of TDD systems, advantages and disadvantages, candidate drug criteria | Preparation of visual slides related to the subject | Öğretim Yöntemleri: Soru-Cevap |
| 3 | Structure and formulations of TDDs | Preparation of visual slides related to the subject | Öğretim Yöntemleri: Tartışma |
| 4 | Production technologies | Preparation of visual slides related to the subject | Öğretim Yöntemleri: Tartışma |
| 5 | Matters to be considered in the selection of production technologies | Preparation of visual slides related to the subject | Öğretim Yöntemleri: Grup Çalışması |
| 6 | Techniques to increase skin permeation | Preparation of visual slides related to the subject | Öğretim Yöntemleri: Tartışma |
| 7 | Investigation of techniques to increase skin permeation | Preparation of visual slides related to the subject | Öğretim Yöntemleri: Tartışma |
| 8 | Mid-Term Exam | Preparation of questions | Ölçme Yöntemleri: Yazılı Sınav |
| 9 | Iontophoresis theory and applications | Preparation of visual slides related to the subject | Öğretim Yöntemleri: Tartışma |
| 10 | Phonophoresis theory and applications | Preparation of visual slides related to the subject | Öğretim Yöntemleri: Soru-Cevap |
| 11 | Examples of TDD systems on the market | Preparation of visual slides related to the subject | Öğretim Yöntemleri: Grup Çalışması |
| 12 | Evaluation of TDD systems on the market | Preparation of visual slides related to the subject | Öğretim Yöntemleri: Grup Çalışması |
| 13 | Developments in TDDs | Preparation of visual slides related to the subject | Öğretim Yöntemleri: Tartışma |
| 14 | In vitro characterization of TDDs | Preparation of visual slides related to the subject | Öğretim Yöntemleri: Soru-Cevap |
| 15 | Quality control of TDDs | Preparation of visual slides related to the subject | Öğretim Yöntemleri: Tartışma |
| 16 | Term Exams | Preparation of questions | Ölçme Yöntemleri: Performans Değerlendirmesi |
| 17 | Term Exams | Preparation of questions | Ölçme Yöntemleri: Yazılı Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 12 | 12 | 144 |
| Out of Class Study (Preliminary Work, Practice) | 2 | 2 | 4 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 1 | 1 | 1 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 1 | 1 |
| Final Exam | 1 | 1 | 1 |
| Total Workload (Hour) | 151 | ||
| Total Workload / 25 (h) | 6,04 | ||
| ECTS | 6 ECTS | ||