TÜRKÇE
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Information
| Unit | INSTITUTE OF MEDICAL SCIENCES |
| PEDIATRIC ONCOLOGY (MASTER) (WITH THESIS) | |
| Code | PEDO503 |
| Name | HLA Typing |
| Term | 2025-2026 Academic Year |
| Term | Spring |
| Duration (T+A) | 3-0 (T-A) (17 Week) |
| ECTS | 5 ECTS |
| National Credit | 3 National Credit |
| Teaching Language | Türkçe |
| Level | Belirsiz |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Prof. Dr. GÜLAY SEZGİN |
| Course Instructor |
The current term course schedule has not been prepared yet.
|
Course Goal / Objective
Understands the importance of HLA system in organ tranplants and disease pathogenesis
Course Content
HLA typing, its importance and applications
Course Precondition
Students expected to know the basics of the HLA system
Resources
https://www.nmdp.org/patients/understanding-transplant/finding-a-donor/hla-typing-matching
Notes
https://www.uptodate.com/contents/human-leukocyte-antigens-hla-a-roadmap
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Defines the basic elements of HLA tissue types |
| LO02 | Lists the HLA tissue types and its use |
| LO03 | Gains competence in HLA typing methods |
| LO04 | Gains competence in use of HLA typing in organ transplants |
| LO05 | Gains competence in use of HLA typing in cellular therapies |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Belirsiz | They gain expertise in donor selection. | 3 |
| PLO02 | Belirsiz | During the stem cell transplantation process, the most suitable graft is selected. | 1 |
| PLO03 | Belirsiz | It lists the characteristics of donors according to the type of stem cell transplant. | |
| PLO04 | Belirsiz | It explains the concepts of haploidentical and allogeneic transplantation. | 2 |
| PLO05 | Belirsiz | It lists the principles for collecting stem cells from cord blood. | |
| PLO06 | Belirsiz | This describes the steps involved in collecting CD34 cells from peripheral blood. | |
| PLO07 | Belirsiz | It describes the necessary conditions for collecting stem cells from bone marrow. |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Definition of HLA and history | Review of relevant textbooks and online resources | Öğretim Yöntemleri: Anlatım |
| 2 | HLA tissue types | Review of relevant textbooks and online resources | Öğretim Yöntemleri: Anlatım, Tartışma, Soru-Cevap |
| 3 | HLA tissue typing methods | Review of relevant textbooks and online resources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 4 | HLA tissue typing laboratory-1 | Review of relevant textbooks and online resources | Öğretim Yöntemleri: Alıştırma ve Uygulama |
| 5 | HLA tissue typing laboratory-2 | Review of relevant textbooks and online resources | Öğretim Yöntemleri: Alıştırma ve Uygulama |
| 6 | HLA nomenclature | Review of relevant textbooks and online resources | Öğretim Yöntemleri: Anlatım |
| 7 | What does HLA match mean? | Review of relevant textbooks and online resources | Öğretim Yöntemleri: Alıştırma ve Uygulama |
| 8 | Mid-Term Exam | Review of the course materials | Ölçme Yöntemleri: Sözlü Sınav |
| 9 | HLA typing in organ transplants | Review of relevant textbooks and online resources | Öğretim Yöntemleri: Anlatım |
| 10 | HLA and disease associations | Review of relevant textbooks and online resources | Öğretim Yöntemleri: Anlatım |
| 11 | HLA tissue typing laboratory-3 | Review of relevant textbooks and online resources | Öğretim Yöntemleri: Alıştırma ve Uygulama |
| 12 | HLA tissue typing laboratory-4 | Review of relevant textbooks and online resources | Öğretim Yöntemleri: Alıştırma ve Uygulama |
| 13 | Homework-1 | Review of relevant textbooks and online resources | Öğretim Yöntemleri: Bireysel Çalışma |
| 14 | Homework-2 | Review of relevant textbooks and online resources | Öğretim Yöntemleri: Bireysel Çalışma |
| 15 | Homework presentation | Review of relevant textbooks and online resources | Öğretim Yöntemleri: Gösteri |
| 16 | Term Exams | Review of the course materials | Ölçme Yöntemleri: Proje / Tasarım |
| 17 | Term Exams | Review of the course materials | Ölçme Yöntemleri: Performans Değerlendirmesi |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 8 | 10 | 80 |
| Out of Class Study (Preliminary Work, Practice) | 2 | 2 | 4 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 6 | 6 | 36 |
| Mid-term Exams (Written, Oral, etc.) | 2 | 2 | 4 |
| Final Exam | 1 | 1 | 1 |
| Total Workload (Hour) | 125 | ||
| Total Workload / 25 (h) | 5,00 | ||
| ECTS | 5 ECTS | ||