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Information
| Unit | FACULTY OF PHARMACY |
| PHARMACY PR. | |
| Code | ECS324 |
| Name | Trace Elements and Their Analysis |
| Term | 2026-2027 Academic Year |
| Semester | 6. Semester |
| Duration (T+A) | 2-0 (T-A) (17 Week) |
| ECTS | 2 ECTS |
| National Credit | 2 National Credit |
| Teaching Language | Türkçe |
| Level | Belirsiz |
| Type | Normal |
| Label | E Elective |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Dr. Öğr. Üyesi SAMET POYRAZ |
| Course Instructor |
The current term course schedule has not been prepared yet.
|
Course Goal / Objective
Bu dersin amacı, eser elementlerin biyolojik sistemlerdeki rolünü, toksikolojik etkilerini ve klinik önemini kavratmak; ayrıca bu elementlerin biyolojik örneklerde tayininde kullanılan temel analitik yaklaşımlar hakkında öğrencilere bütüncül bir bakış açısı kazandırmaktır.
Course Content
Definition, classification, and distribution of trace elements in biological systems; sampling and storage conditions; sources of contamination; basic analytical approaches for trace element determination in biological specimens; biological effects and clinical significance of toxic and essential elements; evaluation of deficiency and toxicity states; biological and analytical assessment of lead, mercury, arsenic, cadmium, zinc, copper, selenium, chromium, nickel, manganese, aluminum, vanadium, and thallium.
Course Precondition
There are no prerequisites for this course. However, basic knowledge of analytical chemistry, general chemistry, and biochemistry is recommended.
Resources
Course notes consist of lecture slides prepared by the instructor, in-class explanations, and materials compiled from selected scientific sources. Herber, R. F. M. and Stoeppler, M. (Eds.). Trace Element Analysis in Biological Specimens. Elsevier. Skoog, D. A., Holler, F. J., and Crouch, S. R. Principles of Analytical Chemistry. Skoog, D. A., Holler, F. J., and Nieman, T. A. Principles of Instrumental Analysis. Gündüz, T. Instrumental Analysis. Gazi Publishing.
Notes
Recent scientific articles on trace element analysis, clinical toxicology, and biological specimen analysis Current review articles on AAS, ICP-OES, and ICP-MS techniques Supplementary resources in pharmaceutical analysis, clinical chemistry, and toxicology International databases such as ScienceDirect, PubMed, and Web of Science
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Classify trace elements according to their essential and toxic properties. |
| LO02 | Explain the roles of trace elements in biological systems. |
| LO03 | Interpret clinical effects associated with deficiency and toxicity of trace elements. |
| LO04 | Describe the basic analytical methods used for trace element determination in biological samples. |
| LO05 | Evaluate sampling procedures, storage conditions, and sources of contamination. |
| LO06 | Explain the biological effects of toxic elements such as lead, mercury, arsenic, and cadmium. |
| LO07 | Assess the physiological roles of essential elements such as zinc, copper, and selenium. |
| LO08 | Compare the biological distribution and metabolism of different trace elements. |
| LO09 | Select appropriate samples and analytical methods for specific purposes. |
| LO10 | Interpret analytical results of trace elements and evaluate them in a clinical context. |
| LO11 | Explain the pharmaceutical and toxicological significance of trace elements. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Have sufficient knowledge in pharmaceutical field and develop the knowledge. | 4 |
| PLO02 | Bilgi - Kuramsal, Olgusal | Comprehends professional knowledge with ethical responsibility through current laws and legislation. | |
| PLO03 | Beceriler - Bilişsel, Uygulamalı | Provides consultancy service to patients, community and health care personnel and evaluates advanced knowledge and skills with a critical approach. | 3 |
| PLO04 | Beceriler - Bilişsel, Uygulamalı | Possessing the knowledge of historical and current developments in the field of Pharmacy, monitoring, evaluation and application of scientific and evidence-based data, and adopting lifelong learning. | 4 |
| PLO05 | Beceriler - Bilişsel, Uygulamalı | Have the knowledge and skills to help provide patient-oriented pharmacy applications and individualized pharmaceutical care by learning the basics of Clinical Pharmacy, | |
| PLO06 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Takes a role in the evaluation and analysis of the events and cases related to the development of pharmacy profession and education. | 4 |
| PLO07 | Yetkinlikler - Öğrenme Yetkinliği | Integrates and develops professional knowledge via different disciplines and uses the acquired knowledge to improve the health level and quality of life of the community. | 3 |
| PLO08 | Yetkinlikler - Öğrenme Yetkinliği | Use effectively the concepts and applications of basic sciences and basic medical sciences in the field of medicine and pharmacy and update the information. | 5 |
| PLO09 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Communicates effectively in writing and speaking. | 2 |
| PLO10 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Practices the profession in accordance with Atatürk's principles and reforms, equipped with universal knowledge, uses Turkish correctly and knows at least one foreign language. | |
| PLO11 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Be an example to society withexternal appearance, demeanor, attitude and behavior for the other professionals and society and with professional identity | |
| PLO12 | Yetkinlikler - Alana Özgü Yetkinlik | Have knowledge about health policies and health economics, pharmacy management and define the problems in pharmaceutical field. | |
| PLO13 | Yetkinlikler - Alana Özgü Yetkinlik | Interprets information about current health and treatment problems and attends meeting on related matters . Plays an active role in community health. | 3 |
| PLO14 | Yetkinlikler - Alana Özgü Yetkinlik | Acquires basic information about diseases, makes decisions about the drugs used in treatment in accordance with rational drug use. | 3 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Introduction | Reading on the definition and classification of trace elements | Öğretim Yöntemleri: Anlatım |
| 2 | Sampling and Contamination | Reading on sampling and sources of contamination | Öğretim Yöntemleri: Anlatım |
| 3 | Sample Preparation | Reading on sample preparation techniques | Öğretim Yöntemleri: Anlatım |
| 4 | Analytical Techniques | Reading on AAS and ICP techniques | Öğretim Yöntemleri: Anlatım |
| 5 | Lead (Pb) | Reading on toxic effects of lead | Öğretim Yöntemleri: Anlatım |
| 6 | Mercury (Hg) | Reading on biological effects of mercury | Öğretim Yöntemleri: Anlatım |
| 7 | Arsenic (As) | Reading on arsenic toxicity | Öğretim Yöntemleri: Anlatım |
| 8 | Mid-Term Exam | Ölçme Yöntemleri: Yazılı Sınav |
|
| 9 | Cadmium (Cd) | Reading on biological effects of cadmium | Öğretim Yöntemleri: Anlatım |
| 10 | Zinc (Zn) | Reading on the biological role of zinc | Öğretim Yöntemleri: Anlatım |
| 11 | Copper (Cu) | Reading on copper metabolism | Öğretim Yöntemleri: Anlatım |
| 12 | Selenium (Se) | Reading on biological effects of selenium | Öğretim Yöntemleri: Anlatım |
| 13 | Chromium (Cr) and Nickel (Ni) | Reading on chromium and nickel | Öğretim Yöntemleri: Anlatım |
| 14 | Manganese (Mn) and Aluminum (Al) | Reading on biological effects of manganese and aluminum | Öğretim Yöntemleri: Anlatım |
| 15 | Vanadium (V), Thallium (Tl) and General Evaluation | Review of previous topics | Öğretim Yöntemleri: Anlatım |
| 16 | Term Exams | Ölçme Yöntemleri: Yazılı Sınav |
|
| 17 | Term Exams | Ölçme Yöntemleri: Yazılı Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 2 | 28 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 1 | 14 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 4 | 4 |
| Final Exam | 1 | 4 | 4 |
| Total Workload (Hour) | 50 | ||
| Total Workload / 25 (h) | 2,00 | ||
| ECTS | 2 ECTS | ||