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Information
| Unit | FACULTY OF PHARMACY |
| PHARMACY PR. | |
| Code | ECS426 |
| Name | Nanomedicine and Nanobiotechnology |
| Term | 2026-2027 Academic Year |
| Semester | 8. Semester |
| Duration (T+A) | 2-0 (T-A) (17 Week) |
| ECTS | 2 ECTS |
| National Credit | 2 National Credit |
| Teaching Language | Türkçe |
| Level | Belirsiz |
| Type | Normal |
| Label | E Elective |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Doç. Dr. METİN YILDIRIM |
| Course Instructor |
The current term course schedule has not been prepared yet.
|
Course Goal / Objective
The aim of this course is to provide students with knowledge and practical understanding of the definition, scope, and application areas of nanomedicine and nanobiotechnology. The course covers the structural and functional principles of nanomedicine and nanobiotechnology, biomaterial–cell interactions, nanobiodevices, nanomedicine applications, nanobiosensors, nanofluids, and the commercialization of nanobiotechnology. In addition, it addresses the current status and future perspectives of nanomedicine and nanobiotechnology.
Course Content
ntroduction to Nanomedicine and Nanobiotechnology Applications of Nanotechnology in Biotechnology and Biomedicine Structural and Functional Principles of Nanomedicine and Nanobiotechnology Biomaterial–Cell Interactions Nanobiodevices Nanobiosensors I Nanobiosensors II Nanoparticles and Biofilms Formation of Hybrid Structures by Combining Nanomaterials with Biological Molecules Nanomedicine I Nanomedicine II Nanofluids Commercialization of Nanobiotechnology Current Status and Future Perspectives of Nanomedicine and Nanobiotechnology
Course Precondition
It is recommended that students have prior knowledge of basic biochemistry and cell biology before taking this course.
Resources
Bionanotechnology: Lessons from Nature, David S. Goodsell, Wiley-Liss; 1 edition, 2004. 2-Bionanotechnology: Global Prospects, CRC; 1 edition, 2008. 3-Charles P. Poole Jr. and Frank J. Owens, Introduction to Nanotechnology, Wiley-Interscience, 1st edition, (2003). 4-Alain Nouailhat, An Introduction to Nanoscience & Nanotechnology, ISTE Ltd and John Wiley & Sons, Inc., (2008)
Notes
Recent scientific articles (indexed in SCI/SCI-E journals) International databases (PubMed, ScienceDirect, Web of Science) Clinical guidelines and protocols E-books and open-access resources National and international conference proceedings Supplementary materials provided by the instructor
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Understands the fundamental concepts, principles, and application areas of nanomedicine; analyzes the structural properties of nanomaterials, their interactions with biological systems, and their roles in targeted diagnosis and therapy; and evaluates nanomedicine applications in terms of biocompatibility, toxicity, and clinical use. |
| LO02 | Acquires knowledge of the application areas of nanomedicine; identifies and explains key uses in drug delivery, diagnostics, imaging, regenerative medicine, and therapeutic interventions, and evaluates their clinical and technological significance. |
| LO03 | Interprets recent approaches in nanomedicine; analyzes current nanotechnological advancements and evaluates smart nanocarrier systems, targeted therapeutic strategies, and innovative diagnostic methods. Additionally, critically assesses their clinical efficacy, biosafety, and potential future applications. |
| LO04 | Understands the fundamental principles of nanobiotechnology; explains the structure and properties of nanomaterials and their interaction mechanisms with biological systems. Additionally, evaluates the applications of nanobiotechnology in diagnostics, therapy, and biotechnology, and analyzes their importance in terms of biocompatibility and safety. |
| LO05 | Acquires knowledge of the application areas of nanobiotechnology; identifies and explains key applications such as drug delivery systems, biosensors, diagnostic and imaging techniques, tissue engineering, and environmental applications. Additionally, evaluates their biomedical and industrial significance. |
| LO06 | Interprets recent approaches in nanobiotechnology; analyzes current research and technological advancements, and evaluates innovative applications such as advanced nanobiosensors, smart nanocarrier systems, and biohybrid structures. Additionally, critically assesses their significance in terms of biosafety, ethics, and clinical applicability. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Have sufficient knowledge in pharmaceutical field and develop the knowledge. | 3 |
| PLO02 | Bilgi - Kuramsal, Olgusal | Comprehends professional knowledge with ethical responsibility through current laws and legislation. | |
| PLO03 | Beceriler - Bilişsel, Uygulamalı | Provides consultancy service to patients, community and health care personnel and evaluates advanced knowledge and skills with a critical approach. | 5 |
| PLO04 | Beceriler - Bilişsel, Uygulamalı | Possessing the knowledge of historical and current developments in the field of Pharmacy, monitoring, evaluation and application of scientific and evidence-based data, and adopting lifelong learning. | |
| PLO05 | Beceriler - Bilişsel, Uygulamalı | Have the knowledge and skills to help provide patient-oriented pharmacy applications and individualized pharmaceutical care by learning the basics of Clinical Pharmacy, | 3 |
| PLO06 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Takes a role in the evaluation and analysis of the events and cases related to the development of pharmacy profession and education. | |
| PLO07 | Yetkinlikler - Öğrenme Yetkinliği | Integrates and develops professional knowledge via different disciplines and uses the acquired knowledge to improve the health level and quality of life of the community. | 5 |
| PLO08 | Yetkinlikler - Öğrenme Yetkinliği | Use effectively the concepts and applications of basic sciences and basic medical sciences in the field of medicine and pharmacy and update the information. | 5 |
| PLO09 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Communicates effectively in writing and speaking. | |
| PLO10 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Practices the profession in accordance with Atatürk's principles and reforms, equipped with universal knowledge, uses Turkish correctly and knows at least one foreign language. | |
| PLO11 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Be an example to society withexternal appearance, demeanor, attitude and behavior for the other professionals and society and with professional identity | |
| PLO12 | Yetkinlikler - Alana Özgü Yetkinlik | Have knowledge about health policies and health economics, pharmacy management and define the problems in pharmaceutical field. | |
| PLO13 | Yetkinlikler - Alana Özgü Yetkinlik | Interprets information about current health and treatment problems and attends meeting on related matters . Plays an active role in community health. | 5 |
| PLO14 | Yetkinlikler - Alana Özgü Yetkinlik | Acquires basic information about diseases, makes decisions about the drugs used in treatment in accordance with rational drug use. |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Introduction to Nanomedicine and Nanobiotechnology | Review of basic concepts of nanotechnology, structural organization at the atomic and molecular levels, fundamental cell biology, biomolecules (proteins, lipids, nucleic acids), and basic principles of biotechnology. | Öğretim Yöntemleri: Anlatım |
| 2 | Applications of nanotechnology in biotechnology and biomedicine | Applications of Nanotechnology in Biotechnology and Biomedicine: Current Approaches and Clinical Uses | Öğretim Yöntemleri: Anlatım |
| 3 | Structural and functional principles of nanomedicine and nanobiotechnology | Review of basic nanotechnology concepts, cell membrane structure and transport mechanisms, biomolecules, and fundamental biochemistry principles. | Öğretim Yöntemleri: Anlatım, Tartışma, Soru-Cevap |
| 4 | Biomaterial–Cell Interactions: Biocompatibility, Surface Properties, and Cellular Responses | Review of cell structure and function, cell membrane and adhesion mechanisms, basic biochemistry, and fundamental biomaterial concepts. | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 5 | Nanobiodevices: Design, Working Principles, and Biomedical Applications | Review of basic nanotechnology concepts, general principles of biosensors, cell biology, and basic electronics/biophysics concepts. | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 6 | Nanobiosensors I: Fundamental Principles, Components, and Detection Mechanisms | Review of basic biochemistry, enzyme kinetics, biomolecules, general principles of sensor systems, and fundamental concepts of nanotechnology. | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 7 | Nanobiosensors II: Advanced Technologies, Design Strategies, and Clinical Applications | Review of fundamental nanobiosensor principles, bioreceptor–transducer systems, properties of nanomaterials, and applications of biosensors. | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 8 | Mid-Term Exam | Ölçme Yöntemleri: Yazılı Sınav |
|
| 9 | Nanoparticles and Biofilms: Structural Properties, Formation Mechanisms, and Biomedical Applications | Review of basic nanotechnology concepts, microbial structure, mechanisms of antibiotic action, and cell surface interactions. | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 10 | Formation of Hybrid Structures by Integrating Nanomaterials with Biological Molecules: Design, Functionalization, and Biomedical Applications | Review of basic nanotechnology principles, structure and function of biomolecules, types of chemical bonding, and fundamental biochemistry concepts. | Öğretim Yöntemleri: Anlatım |
| 11 | Nanomedicine I: Fundamental Concepts, Nanocarrier Systems, and Introduction to Biomedical Applications | Review of basic nanotechnology concepts, mechanisms of drug action, cell biology, and biomolecules. | Öğretim Yöntemleri: Anlatım |
| 12 | Nanomedicine II: Advanced Nanotherapeutic Approaches, Targeted Systems, and Clinical Applications | Review of Nanomedicine I topics, nanocarrier systems, intracellular transport mechanisms, and basic pharmacology and biochemistry. | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 13 | Nanofluids: Physicochemical Properties, Preparation Methods, and Biomedical Applications | Review of basic nanotechnology concepts, physical properties of fluids, nanoparticle structure, and fundamental biochemistry principles. | Öğretim Yöntemleri: Anlatım |
| 14 | Current Status and Future Perspectives of Nanomedicine and Nanobiotechnology: Technological Advances, Clinical Applications, and Emerging Trends | Review of fundamental concepts of nanomedicine and nanobiotechnology, current applications, and biomedical technologies. | Öğretim Yöntemleri: Anlatım |
| 15 | Term Exam | Ölçme Yöntemleri: Yazılı Sınav |
|
| 16 | Term Exams | Ölçme Yöntemleri: Yazılı Sınav |
|
| 17 | Term Exams | Ölçme Yöntemleri: Yazılı Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 2 | 28 |
| Out of Class Study (Preliminary Work, Practice) | 0 | 0 | 0 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 15 | 15 |
| Final Exam | 1 | 15 | 15 |
| Total Workload (Hour) | 58 | ||
| Total Workload / 25 (h) | 2,32 | ||
| ECTS | 2 ECTS | ||