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Information
| Unit | INSTITUTE OF MEDICAL SCIENCES |
| PHARMACOLOGY (MASTER) (WITH THESIS) | |
| Code | EFR522 |
| Name | Urogenital System Pharmacology, In vitro and In vivo Models |
| Term | 2026-2027 Academic Year |
| Term | Fall and Spring |
| Duration (T+A) | 3-0 (T-A) (17 Week) |
| ECTS | 4 ECTS |
| National Credit | 3 National Credit |
| Teaching Language | Türkçe |
| Level | Belirsiz |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Dr. Öğr. Üyesi Didem YILMAZ ORAL |
| Course Instructor |
The current term course schedule has not been prepared yet.
|
Course Goal / Objective
This course aims to provide a theoretical understanding of the physiology and diseases of the urogenital system, the medications used in their treatment, and the experimental models of related diseases.
Course Content
covers the physiology and anatomy of the urogenital system, the pathophysiology of diseases, medications used in treatment, their mechanisms of action, and experimental models of related diseases. Presentations will be supported by studies in experimental pharmacology examining the mechanisms of contraction and relaxation in the tissues of the corpus cavernosum, bladder, prostate, and uterus.
Course Precondition
None.
Resources
Kayaalp S. Oğuz .Akılcı Tedavi Yönünden Tıbbi Farmakoloji 1. ve 2. cilt Pelikan Yayınları,2019; Katzung Bertram G. Basic- Clinical Pharmacology McGraw-Hill Medical Books,2018.
Notes
Current literature
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Defines the physiological and pathophysiological processes of the urogenital system. |
| LO02 | Compares the pharmacological targets of the upper and lower urinary systems. |
| LO03 | Explains and interprets the basic principles of in vitro experimental models. |
| LO04 | Explains and interprets the basic principles of in vivo experimental models. |
| LO05 | Analyzes pharmacological data and dose-response curves. |
| LO06 | Evaluates the contraction/relaxation mechanisms of prostate, corpus cavernosum, bladder, and uterine tissues. |
| LO07 | Gains knowledge about an experimental pharmacology study. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Explain the mechanisms of action of drugs, their pharmacokinetic and pharmacodynamic effects. | 3 |
| PLO02 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Acts in accordance with ethical and legal principles in the field of pharmacology. | |
| PLO03 | Beceriler - Bilişsel, Uygulamalı | Can project and conduct research in the field of pharmacology and analyze and interpret data. | 4 |
| PLO04 | Yetkinlikler - Alana Özgü Yetkinlik | It plays an active role in rational drug use and provides counseling to the patient for the correct use of the drug. | |
| PLO05 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Can convey the current developments or studies in the field of pharmacology verbally or in writing. | |
| PLO06 | Bilgi - Kuramsal, Olgusal | Follows scientific literature and current developments in the field of pharmacology. | 3 |
| PLO07 | Bilgi - Kuramsal, Olgusal | Explain a relationship between the effects, mechanisms of action and drug interactions of drugs. | 3 |
| PLO08 | Bilgi - Kuramsal, Olgusal | Explain the physiopathology of various diseases and evalue the drugs used in the treatment of these diseases. | 3 |
| PLO09 | Beceriler - Bilişsel, Uygulamalı | Knows and uses good laboratory practices. | |
| PLO10 | Beceriler - Bilişsel, Uygulamalı | Uses the theoretical and applied knowledge gained in the field of pharmacology. | 4 |
| PLO11 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Have the ability to take part in in vitro/in vivo animal studies. | 4 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | An overview of the anatomy and physiology of the urogenital system | Rewiew literature and books | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 2 | Upper urinary tract (kidney, ureter), renal hemodynamics, and pharmacological targets | Rewiew literature and books | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 3 | Physiology of the lower urinary tract, neurogenic control, and pharmacological targets | Rewiew literature and books | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 4 | Introduction to in vitro recording systems and physiological solutions used in isolated organ experiments | Rewiew literature and books | Öğretim Yöntemleri: Soru-Cevap, Tartışma, Bireysel Çalışma |
| 5 | Pharmacological data analysis, dose-response curves, EC50 and Emax calculations | Rewiew literature and books | Öğretim Yöntemleri: Soru-Cevap, Anlatım, Tartışma, Bireysel Çalışma |
| 6 | Mechanisms of action and receptors involved in contraction/relaxation responses in isolated bladder tissue | Rewiew literature and books | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Bireysel Çalışma |
| 7 | Mechanisms of action and receptors involved in contraction/relaxation responses in isolated prostate tissue | Rewiew literature and books | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Bireysel Çalışma |
| 8 | Mid-Term Exam | Rewiew literature and books | Ölçme Yöntemleri: Ödev |
| 9 | Mechanisms of action and receptors involved in contraction/relaxation responses in isolated corpus cavernosum tissue | Rewiew literature and books | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Bireysel Çalışma |
| 10 | Mechanisms of action and receptors involved in contraction/relaxation responses in isolated uterine tissue | Rewiew literature and books | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Bireysel Çalışma |
| 11 | Upper urinary tract disorders and pharmacological treatment | Rewiew literature and books | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 12 | Lower urinary tract disorders and pharmacological treatment | Rewiew literature and books | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 13 | In vivo animal models, bladder dysfunction, benign prostatic hyperplasia, and erectile dysfunction | Rewiew literature and books | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Bireysel Çalışma |
| 14 | In vivo measurement techniques, cystometry, intracavernosal pressure measurement, blood pressure monitoring | Rewiew literature and books | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Bireysel Çalışma |
| 15 | General review—student presentations | Rewiew literature and books | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 16 | Term Exams | Rewiew literature and books | Ölçme Yöntemleri: Yazılı Sınav |
| 17 | Term Exams | Rewiew literature and books | Ölçme Yöntemleri: Yazılı Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 3 | 42 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 3 | 42 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 7 | 7 |
| Final Exam | 1 | 15 | 15 |
| Total Workload (Hour) | 106 | ||
| Total Workload / 25 (h) | 4,24 | ||
| ECTS | 4 ECTS | ||